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UniProtKB/Swiss-Prot entry Q9ZPY2


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name LAC6_ARATH
Primary accession number Q9ZPY2
Secondary accession number Q8RY28
Integrated into Swiss-Prot on April 3, 2007
Sequence was last modified on May 1, 1999 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 46)
Name and origin of the protein
Protein name Laccase-6 [Precursor]
Synonyms EC 1.10.3.2
Benzenediol:oxygen oxidoreductase 6
Urishiol oxidase 6
Diphenol oxidase 6
Gene name
Name: LAC6
OrderedLocusNames: At2g46570
ORFNames: F13A10.10
From
Arabidopsis thaliana (Mouse-ear cress) [TaxID: 3702] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
DOI=10.1038/45471; PubMed=10617197 [NCBI, ExPASy, EBI, Israel, Japan]
Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
Nature 402:761-768(1999).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
STRAIN=cv. Columbia;
DOI=10.1126/science.1088305; PubMed=14593172 [NCBI, ExPASy, EBI, Israel, Japan]
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.;
"Empirical analysis of transcriptional activity in the Arabidopsis genome.";
Science 302:842-846(2003).
[3]
TISSUE SPECIFICITY.
DOI=10.1007/s00425-004-1472-6; PubMed=15940465 [NCBI, ExPASy, EBI, Israel, Japan]
McCaig B.C., Meagher R.B., Dean J.F.D.;
"Gene structure and molecular analysis of the laccase-like multicopper oxidase (LMCO) gene family in Arabidopsis thaliana.";
Planta 221:619-636(2005).
[4]
TISSUE SPECIFICITY.
DOI=10.1093/jxb/erl022; PubMed=16804053 [NCBI, ExPASy, EBI, Israel, Japan]
Cai X., Davis E.J., Ballif J., Liang M., Bushman E., Haroldsen V., Torabinejad J., Wu Y.;
"Mutant identification and characterization of the laccase gene family in Arabidopsis.";
J. Exp. Bot. 57:2563-2569(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AC006418; AAD20177.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY078937; AAL84943.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR E84904; E84904.
RefSeq NP_182180.1; -.
UniGene At.53141
3D structure databases
HSSP P37064; 1AOZ. [HSSP ENTRY / PDB]
ModBase Q9ZPY2.
Organism-specific databases
TAIR At2g46570; -.
Gene expression databases
ArrayExpress Q9ZPY2; -.
Family and domain databases
InterPro IPR001117; Cu-oxidase.
IPR011706; Cu-oxidase_2.
IPR011707; Cu-oxidase_3.
IPR002355; Cu_oxidase_Cu_BS.
IPR008972; Cupredoxin.
IPR017761; Laccase.
Graphical view of domain structure.
Gene3D G3DSA:2.60.40.420; Cupredoxin; 3.
Pfam PF00394; Cu-oxidase; 1.
PF07731; Cu-oxidase_2; 1.
PF07732; Cu-oxidase_3; 1.
Pfam graphical view of domain structure.
PROSITE PS00079; MULTICOPPER_OXIDASE1; 1.
PS00080; MULTICOPPER_OXIDASE2; 1.
BLOCKS Q9ZPY2.
Genome annotation databases
GeneID 819269; -.
GenomeReviews CT485783_GR; AT2G46570.
KEGG ath:AT2G46570; -.
NMPDR fig|3702.1.peg.11842; -.
Other
ProtoNet Q9ZPY2.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Alternative splicing; Apoplast; Complete proteome; Copper; Glycoprotein; Lignin degradation; Metal-binding; Oxidoreductase; Repeat; Secreted; Signal.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
SIGNAL   1    29  29     Potential. 
CHAIN   30   569  540     Laccase-6. PRO_0000283634
DOMAIN   37   153  117     Plastocyanin-like 1. 
DOMAIN   163   315  153     Plastocyanin-like 2. 
DOMAIN   417   553  137     Plastocyanin-like 3. 
METAL   87    87        Copper 1; type 2 (By similarity). 
METAL   89    89        Copper 2; type 3 (By similarity). 
METAL   132   132        Copper 2; type 3 (By similarity). 
METAL   134   134        Copper 3; type 3 (By similarity). 
METAL   472   472        Copper 4; type 1 (By similarity). 
METAL   475   475        Copper 1; type 2 (By similarity). 
METAL   477   477        Copper 3; type 3 (By similarity). 
METAL   532   532        Copper 3; type 3 (By similarity). 
METAL   533   533        Copper 4; type 1 (By similarity). 
METAL   534   534        Copper 2; type 3 (By similarity). 
METAL   538   538        Copper 4; type 1 (By similarity). 
METAL   543   543        Copper 4; type 1 (By similarity). 
CARBOHYD   83    83        N-linked (GlcNAc...) (Potential). 
CARBOHYD   208   208        N-linked (GlcNAc...) (Potential). 
CARBOHYD   303   303        N-linked (GlcNAc...) (Potential). 
CARBOHYD   319   319        N-linked (GlcNAc...) (Potential). 
CARBOHYD   392   392        N-linked (GlcNAc...) (Potential). 
CARBOHYD   438   438        N-linked (GlcNAc...) (Potential). 
CARBOHYD   444   444        N-linked (GlcNAc...) (Potential). 
VAR_SEQ   1   235        Missing (in isoform 2). VSP_024345
VAR_SEQ   296   327        Missing (in isoform 2). VSP_024346
VAR_SEQ   528   568        LWLLHCHFDIHQTWGMSTMFIVKNGKKVQESLPHPP ADLPK -> ILLHKTPKHHNTYDI (in isoform 2). VSP_024347
Sequence information
Length: 569 AA [This is the length of the unprocessed precursor] Molecular weight: 63901 Da [This is the MW of the unprocessed precursor] CRC64: 3BA02CB6A0C44238 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MTSSAVPSLF RLSFLLFTLQ VMNIGRIGAA TRFYQFKVQT IRLTRLCQTN EIVTVNKKFP 

        70         80         90        100        110        120 
GPAISAQEDD RIVIKVINMT PYNTTIHWHG IKQKRSCWYD GPSYITQCPI QSGQSFTYNF 

       130        140        150        160        170        180 
KVAQQKGTFL WHAHFSWLRA TVYGPLIVYP KASVPYPFKK PFNEHTILLG EYWLKNVVEL 

       190        200        210        220        230        240 
EQHVLESGGP PPPADAFTIN GQPGPNYNCS SKDVYEIQIV PRKIYLLRLI NAGINMETFF 

       250        260        270        280        290        300 
TIANHRLTIV EVDGEYTKPY TTERVMLVPG QTMNILVTAD QTVGRYSMAM GPYESAKNVK 

       310        320        330        340        350        360 
FQNTSAIANF QYIGALPNNV TVPAKLPIFN DNIAVKTVMD GLRSLNAVDV PRNIDAHLFI 

       370        380        390        400        410        420 
TIGLNVNKCN SENPNNKCQG PRKGRLAASM NNISFIEPKV SILEAYYKQL EGYFTLDFPT 

       430        440        450        460        470        480 
TPEKAYDFVN GAPNDIANDT QAANGTRAIV FEYGSRIQII FQNTGTLTTE NHPIHLHGHS 

       490        500        510        520        530        540 
FYVIGYGTGN YDQQTAKFNL EDPPYLNTIG VPVGGWAAIR FVANNPGLWL LHCHFDIHQT 

       550        560 
WGMSTMFIVK NGKKVQESLP HPPADLPKC 

Q9ZPY2 in FASTA format

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