[1]	NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Kitamura M., Kojima S., Akutsu H., Kumagai I., Nakaya T.; "Catalase from strictly anaerobic bacteria, Desulfovibrio vulgaris (Miyazaki F)."; Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases.

Comments

FUNCTION: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.
CATALYTIC ACTIVITY: 2 H₂O₂ = O₂ + 2 H₂O.
COFACTOR: Heme group.
SIMILARITY: Belongs to the catalase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AB020341; BAA34670.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

3D structure databases

HSSP

P42321; 1M85. [HSSP ENTRY / PDB]

SMR

Q9ZN99; 5-479.

ModBase

Q9ZN99.

Family and domain databases

InterPro

IPR002226; Catalase.
IPR011614; Catalase_N.
Graphical view of domain structure.

Gene3D

G3DSA:2.40.180.10; Catalase_N; 1.

PANTHER

PTHR11465; Catalase; 1.

Pfam

PF00199; Catalase; 1.
Pfam graphical view of domain structure.

PRINTS

PR00067; CATALASE.

ProDom

PD000510; Catalase; 1.
[Domain structure / List of seq. sharing at least 1 domain]

PROSITE

PS00437; CATALASE_1; 1.
PS00438; CATALASE_2; 1.

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Heme; Hydrogen peroxide; Iron; Metal-binding; Oxidoreductase; Peroxidase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 479`	`479`	`Catalase.`	`PRO_0000084985`
`ACT_SITE`	`54 54`		`By similarity.`
`ACT_SITE`	`127 127`		`By similarity.`
`METAL`	`337 337`		`Iron (heme axial ligand) (By similarity).`

Sequence information

Length: 479 AA [This is the length of the unprocessed precursor]

Molecular weight: 54549 Da [This is the MW of the unprocessed precursor]

CRC64: 4CD97480AB6FD475 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MTKHKLTTNA GAPVPDNQNA MTAGPRGPML LQDVWFLEKL AHFDREVIPE RRMHAKGSGA 

        70         80         90        100        110        120 
YGTFTVTHDI TSYTKAALFS KIGKKTDLFV RFSTVAGERG AATAERDIRG FAIKFYTEQG 

       130        140        150        160        170        180 
NWDLVGNNTP VFFLRDPLKF PDLNHAVKRD PRTNMRSAKN NWDFWTSLPE ALHQVTVVMS 

       190        200        210        220        230        240 
DRGIPASYRH MHGFGSHTFS FISPDNQRYW VKFHLRTQQG IKNLTDAEAE AIVARDRESH 

       250        260        270        280        290        300 
QRDLYDSIER GDFPRWTMYV QVMPEKDAEK LPYHPFDLTK VWFHKDCPLI EVGVLELNRN 

       310        320        330        340        350        360 
PENYFAEVEQ AAFNPANVVP GISFSPDKML QGRLFSYGDA HRYRLGVNHH LIPVNAARCP 

       370        380        390        400        410        420 
VHSYHRDGAM RVDGNHGSTL AYEPNSYGEW QEQPDFAEPP LAIRGDAAHW NFREDADYYD 

       430        440        450        460        470 
QPGRLFRLMT PQQQDELFQN TARAMGDAPE EIKRRHVGNC AKADPAYGAG VARALGLKM

Q9ZN99 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools