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UniProtKB/Swiss-Prot entry Q9UTM8


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name SSDH2_SCHPO
Primary accession number Q9UTM8
Secondary accession numbers None
Integrated into Swiss-Prot on November 13, 2007
Sequence was last modified on May 1, 2000 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 37)
Name and origin of the protein
Protein name Putative succinate-semialdehyde dehydrogenase C139.05 [NADP+]
Synonyms SSDH
EC 1.2.1.16
Gene name
ORFNames: SPAC139.05
From
Schizosaccharomyces pombe (Fission yeast) [TaxID: 4896] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 38366 / 972;
DOI=10.1038/nature724; PubMed=11859360 [NCBI, ExPASy, EBI, Israel, Japan]
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M., Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.;
"The genome sequence of Schizosaccharomyces pombe.";
Nature 415:871-880(2002).
[2]
SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
DOI=10.1038/nbt1222; PubMed=16823372 [NCBI, ExPASy, EBI, Israel, Japan]
Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.;
"ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.";
Nat. Biotechnol. 24:841-847(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CU329670; CAB59619.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T37606; T37606.
RefSeq NP_593172.1; -.
3D structure databases
HSSP P05091; 1O04. [HSSP ENTRY / PDB]
ModBase Q9UTM8.
Organism-specific databases
GeneDB_Spombe SPAC139.05; -.
Gene expression databases
ArrayExpress Q9UTM8; -.
Ontologies
GO
GO:0005829; Cellular component: cytosol (inferred from direct assay from GeneDB_SPombe).
QuickGo view.
Family and domain databases
InterPro IPR016160; Ald_DHase_CS.
IPR016162; Ald_DHase_N.
IPR015590; Aldehyde_DHase.
IPR010102; Succ_semiAld_DHase.
Graphical view of domain structure.
Gene3D G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1.
PANTHER PTHR11699; Aldehyde_dehyd; 1.
Pfam PF00171; Aldedh; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR01780; SSADH; 1.
PROSITE PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PS00687; ALDEHYDE_DEHYDR_GLU; 1.
BLOCKS Q9UTM8.
Genome annotation databases
GeneID 2541647; -.
KEGG spo:SPAC139.05; -.
NMPDR fig|4896.1.peg.3142; -.
Other
ProtoNet Q9UTM8.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   493  493     Putative succinate-semialdehyde dehydrogenase C139.05 [NADP+]. PRO_0000310352
NP_BIND   242   247  6     NAD or NADP (By similarity). 
ACT_SITE   264   264        By similarity. 
ACT_SITE   298   298        By similarity. 
Sequence information
Length: 493 AA [This is the length of the unprocessed precursor] Molecular weight: 53306 Da [This is the MW of the unprocessed precursor] CRC64: 203BC61AA4F20A9B [This is a checksum on the sequence]
        10         20         30         40         50         60 
MAPQFKRPEL FGFDKSHAQS FVQGKWISSP NNKTFEVDNP ATGEIIGKVA DVSVEETKKA 

        70         80         90        100        110        120 
ISAANEAFKT YKNFTHVQRS QLLERWAELI MENKDDLVKM LTLENGKPLS QAEMEVTTCS 

       130        140        150        160        170        180 
GYLKWYAAEA VRTFGDVAPS SLQSQNFLIS IKQPVGVSAL ITPWNFPAAM IARKGGAALA 

       190        200        210        220        230        240 
AGCTAIFLPA FRTPYVCLGL VRLAQEAGFP DGVLNVITSS DASAHGKELT TNPIVRKVSF 

       250        260        270        280        290        300 
TGSTNVGKIL MGQSASTIKK VSMELGGNAP FIVFPDFPID QAVESFCTIK FNSCGQVCVC 

       310        320        330        340        350        360 
PNRVYVHKNV YDEFVSKLTE KVKTIKVGDG FDSSSAVGPL ISQDGCKKVS KHIEDAVSKG 

       370        380        390        400        410        420 
AKITVGGKEI SSSKGYFFEP TVLSGVTQDM LVASEETFGP LASVFKFDDT EEVIEWANDS 

       430        440        450        460        470        480 
DVGLAGYVFT NNLSTMIHVA KELEVGLVGA NIEMVDEPFI SFGGIKQSGF GKEAGRLGVQ 

       490 
EFMVVKEINL KTL 

Q9UTM8 in FASTA format

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