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UniProtKB/Swiss-Prot entry Q9US47


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name SSDH1_SCHPO
Primary accession number Q9US47
Secondary accession numbers None
Integrated into Swiss-Prot on November 13, 2007
Sequence was last modified on May 1, 2000 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 38)
Name and origin of the protein
Protein name Putative succinate-semialdehyde dehydrogenase C1002.12c [NADP+]
Synonyms SSDH
EC 1.2.1.16
Gene name
ORFNames: SPAC1002.12c
From
Schizosaccharomyces pombe (Fission yeast) [TaxID: 4896] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 38366 / 972;
DOI=10.1038/nature724; PubMed=11859360 [NCBI, ExPASy, EBI, Israel, Japan]
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M., Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.;
"The genome sequence of Schizosaccharomyces pombe.";
Nature 415:871-880(2002).
[2]
SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
DOI=10.1038/nbt1222; PubMed=16823372 [NCBI, ExPASy, EBI, Israel, Japan]
Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.;
"ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.";
Nat. Biotechnol. 24:841-847(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CU329670; CAB65612.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_593499.1; -.
3D structure databases
HSSP P51977; 1BXS. [HSSP ENTRY / PDB]
ModBase Q9US47.
Organism-specific databases
GeneDB_Spombe SPAC1002.12c; -.
Gene expression databases
ArrayExpress Q9US47; -.
Ontologies
GO
GO:0005829; Cellular component: cytosol (inferred from direct assay from GeneDB_SPombe).
QuickGo view.
Family and domain databases
InterPro IPR016160; Ald_DHase_CS.
IPR016162; Ald_DHase_N.
IPR015590; Aldehyde_DHase.
IPR010102; Succ_semiAld_DHase.
Graphical view of domain structure.
Gene3D G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1.
PANTHER PTHR11699; Aldehyde_dehyd; 1.
Pfam PF00171; Aldedh; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR01780; SSADH; 1.
PROSITE PS00687; ALDEHYDE_DEHYDR_GLU; 1.
BLOCKS Q9US47.
Genome annotation databases
GeneID 2543267; -.
KEGG spo:SPAC1002.12c; -.
NMPDR fig|4896.1.peg.3469; -.
Other
ProtoNet Q9US47.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   498  498     Putative succinate-semialdehyde dehydrogenase C1002.12c [NADP+]. PRO_0000310351
NP_BIND   247   252  6     NAD or NADP (By similarity). 
ACT_SITE   269   269        By similarity. 
ACT_SITE   303   303        By similarity. 
Sequence information
Length: 498 AA [This is the length of the unprocessed precursor] Molecular weight: 53272 Da [This is the MW of the unprocessed precursor] CRC64: C43A5114E401EB1E [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSTSSKLSTN IKDLSLFDLE EFPARSYIGG KWVTAASGKT FDVENPGLNE TLAPVTDMSV 

        70         80         90        100        110        120 
EETRKAIKVA HEAFLSYRNS DIKERYAILR RWYDLIMENA DDLATMMTLE NGKALGDAKG 

       130        140        150        160        170        180 
EVVYAAKFID WFAGEALRIS GDSSMSSNPQ NRIITIKQPV GVVGIITPWN FPAAMITRKV 

       190        200        210        220        230        240 
GAALAAGCTV VIRPAAETPF TALALAKLAE RAGVPAGVLN MVTANSPSEH GIELTTNPLI 

       250        260        270        280        290        300 
RKVSFTGSTN VGKILAKQSS STLKKLSLEL GGNAPFIVFE DADLEKAADA LMACKFRGSG 

       310        320        330        340        350        360 
QTCVCANRIY VHSSVYDAFV DLVTERVSKF KLGYGLDAGV THGPLISEKA ISKVKQHVED 

       370        380        390        400        410        420 
AVQKGGVVVT GGKVASNLGP MYFEPTVIIN AKQGMLISEE ETFGPVGALF KFDTEDEVVA 

       430        440        450        460        470        480 
WANDSPVGLA GYLFSKDISR VFRVGEALQV GMVGCNTGLV SDVLSPFGGV KESGFGREGS 

       490 
KYGISEYLDI KSLTISTL 

Q9US47 in FASTA format

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