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UniProtKB/Swiss-Prot entry Q9Q8Z2

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name NTP1_RFVKA
Primary accession number Q9Q8Z2
Secondary accession numbers None
Integrated into Swiss-Prot on December 1, 2000
Sequence was last modified on May 1, 2000 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 47)
Name and origin of the protein
Protein name Nucleoside triphosphatase I
Synonyms EC 3.6.1.15
Nucleoside triphosphate phosphohydrolase I
NPH I
Gene name
Name: NPH1
OrderedLocusNames: s086L
From
Rabbit fibroma virus (strain Kasza) (RFV) (Shope fibroma virus (strain Kasza)) [TaxID: 10272] 
Taxonomy Viruses; dsDNA viruses, no RNA stage; Poxviridae; Chordopoxvirinae; Leporipoxvirus.
Virus host Oryctolagus cuniculus (Rabbit) [TaxID: 9986]
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1006/viro.1999.0002; PubMed=10562495 [NCBI, ExPASy, EBI, Israel, Japan]
Willer D.O., McFadden G., Evans D.H.;
"The complete genome sequence of shope (Rabbit) fibroma virus.";
Virology 264:319-343(1999).
[2]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 26-632.
DOI=10.1016/0168-1702(92)90104-H; PubMed=1329373 [NCBI, ExPASy, EBI, Israel, Japan]
Strayer D.S., Jerng H.H.;
"Sequence and analysis of the BamHI 'D' fragment of Shope fibroma virus: comparison with similar regions of related poxviruses.";
Virus Res. 25:117-132(1992).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AF170722; AAF17970.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_051975.1; -.
3D structure databases
ModBase Q9Q8Z2.
Ontologies
GO
GO:0005524; Molecular function: ATP binding (inferred from electronic annotation from InterPro).
GO:0003677; Molecular function: DNA binding (inferred from electronic annotation from InterPro).
GO:0004386; Molecular function: helicase activity (inferred from electronic annotation from InterPro).
GO:0006350; Biological process: transcription (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR014001; DEAD-like_N.
IPR001650; DNA/RNA_helicase_C.
IPR014021; Helicase_SF1/SF2_ATP-bd.
IPR013676; NPHI_C.
IPR000330; SNF2_N.
Graphical view of domain structure.
Pfam PF00271; Helicase_C; 1.
PF08469; NPHI_C; 1.
PF00176; SNF2_N; 1.
Pfam graphical view of domain structure.
SMART SM00487; DEXDc; 1.
SM00490; HELICc; 1.
SMART graphical view of domain structure.
PROSITE PS51192; HELICASE_ATP_BIND_1; 1.
PS51194; HELICASE_CTER; 1.
PROSITE graphical view of domain structure (profiles).
ProtoNet Q9Q8Z2.
Genome annotation databases
GeneID 1486931; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Hydrolase; Nucleotide-binding; Transcription.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   632  632     Nucleoside triphosphatase I. PRO_0000099096
DOMAIN   42   204  163     Helicase ATP-binding. 
DOMAIN   367   532  166     Helicase C-terminal. 
NP_BIND   55    62  8     ATP (By similarity). 
MOTIF   141   144  4     DEXH box. 
CONFLICT   404   404        F -> V (in Ref. 2). 
CONFLICT   496   496        H -> T (in Ref. 2). 
Sequence information
Length: 632 AA [This is the length of the unprocessed precursor] Molecular weight: 72883 Da [This is the MW of the unprocessed precursor] CRC64: 2579BE4806A92F06 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSVHHAAYID YALRVTENMT DVMTGSDTVT LKSYQHFVSR VFLGLDKMHS LLLFHETGVG 

        70         80         90        100        110        120 
KTITTVFILK HLKDVYTNWI IILLVKKALV EDPWTYSITK YAPEILKDCI FITYDDKNFH 

       130        140        150        160        170        180 
NKFFTNIKTI SSRSRLCIII DECHNFISKS IVKEDGKQRP TKSVYNYLLK NVALHHHKLI 

       190        200        210        220        230        240 
CLSATPIVNS VKEFIMLVNL LRPKILNNIS LFENKRLINE SELINKLGAI CSYIVTNEFS 

       250        260        270        280        290        300 
IFDDVEGSAT FAKKNVYFQY VNMTQKQEQV YQKAKSAELK AGTSSFRIYR RMAATFTFDT 

       310        320        330        340        350        360 
FLDKTDKTPE EIVNEQVTLY KDFEKFIKTK KFSDHALSHF KKGQSLNGTS SADDISFLNE 

       370        380        390        400        410        420 
LREHSCKFTD VCLRILASPG KCLVFEPFVN QSGINILLLY FSAFNISYIE FSSRTKNTRV 

       430        440        450        460        470        480 
QSVAEFNKRE NTNGDLIKTC VFSLSGGEGI SFFSINDIFI LDMTWNEASL RQIIGRAIRL 

       490        500        510        520        530        540 
NSHVLTPEHR RYVYVHFIIA RLSNGDPTVD EDLLDIIRNK SKEFTQLFKV FKHTSIEWIY 

       550        560        570        580        590        600 
EHQTNFSPVD DESGWGALIS RSIDENPTTK RVPRIARGQN IWYSHSNRMI TVYKGFKTDD 

       610        620        630 
GRLFDSDGNF IQTIQANPVI KIHNNKLVYV LD
Q9Q8Z2 in FASTA format

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