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UniProtKB/Swiss-Prot entry Q9P7Y7


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name P5CR_SCHPO
Primary accession number Q9P7Y7
Secondary accession numbers None
Integrated into Swiss-Prot on March 27, 2002
Sequence was last modified on October 1, 2000 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 41)
Name and origin of the protein
Protein name Pyrroline-5-carboxylate reductase
Synonyms P5C reductase
P5CR
EC 1.5.1.2
Gene name
Name: pro3
ORFNames: SPAPYUG7.05
From
Schizosaccharomyces pombe (Fission yeast) [TaxID: 4896] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 38366 / 972;
DOI=10.1038/nature724; PubMed=11859360 [NCBI, ExPASy, EBI, Israel, Japan]
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M., Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.;
"The genome sequence of Schizosaccharomyces pombe.";
Nature 415:871-880(2002).
[2]
NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-96.
STRAIN=ATCC 38366 / 972;
PubMed=11041002 [NCBI, ExPASy, EBI, Israel, Japan]
Shpakovski G.V., Baranova G.M.;
"Chromosomal localization of the rpb9+ and tfa1+ genes encoding components of the mRNA synthesis machinery of Schizosaccharomyces pombe.";
Bioorg. Khim. 26:623-630(2000).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CU329670; CAB66314.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AF237418; AAL55659.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T50305; T50305.
RefSeq NP_594706.1; -.
3D structure databases
ModBase Q9P7Y7.
Enzyme and pathway databases
BioCyc SPOM-XXX-01:SPOM-XXX-01-002787-MON; -.
Organism-specific databases
GeneDB_Spombe SPAPYUG7.05; -.
Gene expression databases
ArrayExpress Q9P7Y7; -.
Ontologies
GO
GO:0005829; Cellular component: cytosol (inferred from direct assay from GeneDB_SPombe).
QuickGo view.
Family and domain databases
InterPro IPR004455; NADP_OxRdtase_F420.
IPR000304; P5CR.
Graphical view of domain structure.
PANTHER PTHR11645; P5CR; 1.
Pfam PF03807; F420_oxidored; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000193; Pyrrol-5-carb_rd; 1.
TIGRFAMs TIGR00112; proC; 1.
PROSITE PS00521; P5CR; 1.
BLOCKS Q9P7Y7.
Genome annotation databases
GeneID 2543212; -.
KEGG spo:SPAPYUG7.05; -.
NMPDR fig|4896.1.peg.4676; -.
Other
ProtoNet Q9P7Y7.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Complete proteome; NADP; Oxidoreductase; Proline biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   282  282     Pyrroline-5-carboxylate reductase. PRO_0000187327
Sequence information
Length: 282 AA [This is the length of the unprocessed precursor] Molecular weight: 29875 Da [This is the MW of the unprocessed precursor] CRC64: 8874A4CB98690CF7 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSGFCVLGCG TMGKALLTGI FDSIAENGND VSDEIIIPNK FYACVKFPKE KEDVQKLFGD 

        70         80         90        100        110        120 
RVKVVMGAKE NAEMAAISNV LLLSCKPQAA EDVLNSPKMK EALKGKLILS ILAGKTISSL 

       130        140        150        160        170        180 
QSMLDESTRV IRIMPNTASR IRESMSVICP GPNATEEDIK FAEWVFNGIG RSMKLPEKLI 

       190        200        210        220        230        240 
DAATAVCGSG PAFVATMIEA MTDGGVMMGI PFPQAQELAA QTMVGTGRMV LQGQHPAMIR 

       250        260        270        280 
NDVSTPAGCT ISGLLALEDG KIRSTIARGI EQATKTASGL GK 

Q9P7Y7 in FASTA format

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