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UniProtKB/Swiss-Prot entry Q9P3I3


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ARGD_NEUCR
Primary accession number Q9P3I3
Secondary accession number Q1K8R4
Integrated into Swiss-Prot on September 27, 2004
Sequence was last modified on October 1, 2000 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 45)
Name and origin of the protein
Protein name Acetylornithine aminotransferase, mitochondrial [Precursor]
Synonyms ACOAT
EC 2.6.1.11
Gene name
Name: arg-8
ORFNames: B7F21.110, NCU05410
From
Neurospora crassa [TaxID: 5141] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes; Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987;
DOI=10.1093/nar/gkg293; PubMed=12655011 [NCBI, ExPASy, EBI, Israel, Japan]
Mannhaupt G., Montrone C., Haase D., Mewes H.-W., Aign V., Hoheisel J.D., Fartmann B., Nyakatura G., Kempken F., Maier J., Schulte U.;
"What's in the genome of a filamentous fungus? Analysis of the Neurospora genome sequence.";
Nucleic Acids Res. 31:1944-1954(2003).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987;
DOI=10.1038/nature01554; PubMed=12712197 [NCBI, ExPASy, EBI, Israel, Japan]
Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D., Jaffe D.B., FitzHugh W., Ma L.-J., Smirnov S., Purcell S., Rehman B., Elkins T., Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M., Qui D., Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M., Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U., Kothe G.O., Jedd G., Mewes H.-W., Staben C., Marcotte E., Greenberg D., Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S., Kamal M., Kamvysselis M., Mauceli E.W., Bielke C., Rudd S., Frishman D., Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S., Cogoni C., Macino G., Catcheside D.E.A., Li W., Pratt R.J., Osmani S.A., DeSouza C.P.C., Glass N.L., Orbach M.J., Berglund J.A., Voelker R., Yarden O., Plamann M., Seiler S., Dunlap J.C., Radford A., Aramayo R., Natvig D.O., Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I., Sachs M.S., Lander E.S., Nusbaum C., Birren B.W.;
"The genome sequence of the filamentous fungus Neurospora crassa.";
Nature 422:859-868(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AL389901; CAB97483.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AABX02000030; EAA34262.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T51030; T51030.
T51048; T51048.
RefSeq XP_963498.1; -.
3D structure databases
HSSP P12995; 1QJ3. [HSSP ENTRY / PDB]
ModBase Q9P3I3.
Ontologies
GO
GO:0005759; Cellular component: mitochondrial matrix (inferred from electronic annotation from UniProtKB-SubCell).
GO:0003992; Molecular function: acetylornithine transaminase activity (inferred from electronic annotation from EC).
GO:0030170; Molecular function: pyridoxal phosphate binding (inferred from electronic annotation from InterPro).
GO:0006526; Biological process: arginine biosynthetic process (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR005814; Aminotrans_3.
IPR004636; ArgD_aminotrans.
IPR015421; PyrdxlP-dep_Trfase_major_sub1.
Graphical view of domain structure.
Gene3D G3DSA:3.40.640.10; PyrdxlP-dep_Trfase_major_sub1; 1.
PANTHER PTHR11986; Aminotrans_3; 1.
PTHR11986:SF19; ArgD_aminotrans; 1.
Pfam PF00202; Aminotran_3; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00707; argD; 1.
PROSITE PS00600; AA_TRANSFER_CLASS_3; 1.
ProtoNet Q9P3I3.
Genome annotation databases
GeneID 3879652; -.
KEGG ncr:NCU05410; -.
NMPDR fig|5141.1.peg.3198; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Aminotransferase; Arginine biosynthesis; Complete proteome; Mitochondrion; Pyridoxal phosphate; Transferase; Transit peptide.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
TRANSIT   1     ?        Mitochondrion (Potential). 
CHAIN   ?   461        Acetylornithine aminotransferase, mitochondrial. PRO_0000002080
BINDING   312   312        Pyridoxal phosphate (covalent) (By similarity). 
Sequence information
Length: 461 AA [This is the length of the unprocessed precursor] Molecular weight: 49408 Da [This is the MW of the unprocessed precursor] CRC64: 97AC5990936999A0 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MAFRTALRRV AAVNAAPATR LAGAGAGAAT AARRSYATAS QLTHPDPTED SPSGKMVREH 

        70         80         90        100        110        120 
VPYMVTTYSR PPPVFVKGKG SYLWDLEDRK YLDFTSGIAV NSLGHCDEEF SKIIAEQAQE 

       130        140        150        160        170        180 
LVHASNLYYN PWTGALSKLL VESTKASGGM HDASSVFVCN SGSEANEAGI KFARKVGKVL 

       190        200        210        220        230        240 
DPSGSKVEIV CFQNAFHGRT MGSLSATPNP KYQAPFAPMV PGFKVGTYND IAAIPSLVTE 

       250        260        270        280        290        300 
KTCSVIVEPI QGEGGVMPAT EEFLVALGKR CREVGALLHY DEIQCGLART GTFWAHSSLP 

       310        320        330        340        350        360 
KEAHPDILTT AKAIGNGFPI AATIVNEHVA SKIKVGDHGT TFGGNPLACR LAHYIVGRLA 

       370        380        390        400        410        420 
DKQLQEGVKA KSEVFLRGFE KLRNKFPSLV KEVRGKGLIL GLQLSEDPTP VIKAARERGL 

       430        440        450        460 
LVITAGTNTL RFVPSLLVTE GEIEEGLKIL EESFEAVMVK A 

Q9P3I3 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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