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UniProtKB/Swiss-Prot entry Q9KNW4


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ASTD_VIBCH
Primary accession number Q9KNW4
Secondary accession numbers None
Integrated into Swiss-Prot on November 28, 2006
Sequence was last modified on October 1, 2000 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 39)
Name and origin of the protein
Protein name N-succinylglutamate 5-semialdehyde dehydrogenase
Synonyms EC 1.2.1.71
Succinylglutamic semialdehyde dehydrogenase
SGSD
Gene name
Name: astD
OrderedLocusNames: VC_2616
From
Vibrio cholerae [TaxID: 666] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 39315 / El Tor Inaba N16961 / Serotype O1;
DOI=10.1038/35020000; PubMed=10952301 [NCBI, ExPASy, EBI, Israel, Japan]
Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L., Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R., Nelson K.E., Read T.D., Tettelin H., Richardson D.L., Ermolaeva M.D., Vamathevan J.J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.A., Utterback T.R., Fleischmann R.D., Nierman W.C., White O., Salzberg S.L., Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
"DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae.";
Nature 406:477-483(2000).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE003852; AAF95757.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR D82054; D82054.
RefSeq NP_232244.1; -.
3D structure databases
HSSP P51977; 1BXS. [HSSP ENTRY / PDB]
ModBase Q9KNW4.
Ontologies
GO
GO:0019544; Biological process: arginine catabolic process to glutamate (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01174; -; 1.
PBIL [Tree]
InterPro IPR016160; Ald_DHase_CS.
IPR016162; Ald_DHase_N.
IPR015590; Aldehyde_DHase.
IPR017649; SuccinylGlu_semiald_DH_AstD.
Graphical view of domain structure.
Gene3D G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1.
PANTHER PTHR11699; Aldehyde_dehyd; 1.
Pfam PF00171; Aldedh; 1.
Pfam graphical view of domain structure.
PROSITE PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PS00687; ALDEHYDE_DEHYDR_GLU; 1.
BLOCKS Q9KNW4.
Genome annotation databases
GeneID 2615633; -.
GenomeReviews AE003852_GR; VC_2616.
KEGG vch:VC2616; -.
TIGR VC_2616; -.
Phylogenomic databases
HOGENOM Q9KNW4; -.
Other
ProtoNet Q9KNW4.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Arginine metabolism; Complete proteome; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   485  485     N-succinylglutamate 5-semialdehyde dehydrogenase. PRO_0000262431
NP_BIND   220   225  6     NAD (By similarity). 
ACT_SITE   243   243        By similarity. 
ACT_SITE   278   278        By similarity. 
Sequence information
Length: 485 AA [This is the length of the unprocessed precursor] Molecular weight: 52193 Da [This is the MW of the unprocessed precursor] CRC64: 07E9FF9E24C091F2 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MTHWIAGEWV AGTGEKLESH TPYSHELLWQ GYSASGEQVD AAVKAARRAF LDWKKRPFAE 

        70         80         90        100        110        120 
REQKVLAFAE LVKANSEQIA QVIAKETGKP LWETRTEAAS IAGKIAISIR AYHERTGETV 

       130        140        150        160        170        180 
REAAGNQLVL RHRPLGVMAV FGPYNFPGHL PNGHIVPALL AGNTVVFKPS EQTPWTGEVL 

       190        200        210        220        230        240 
MQLWQQAGLP AGVINLVQGS KETGIALAQS RGIDGLLFTG SANTGHLLHR QFAGQPDKML 

       250        260        270        280        290        300 
ALEMGGNNPM VISEHYGDLD ATVYTIIQSA FISSGQRCTC VRRLYVPQGT KGDALLDKLV 

       310        320        330        340        350        360 
SVTAKLRIDQ PFAEPAPFMG PLVSEAAAQA ILKAQADLQA LGGKSLLEAR ALHAAFITPA 

       370        380        390        400        410        420 
IIDVTAIERL PDDEYFGPLL QVVRYQTLAQ AVELANDTRF GLSAGLVSTD DGEWDYFVEH 

       430        440        450        460        470        480 
IRAGIVNRNR QLTGASGDAP FGGPGASGNL RPSAFYAADY CAYPMASMEG DTTLLPATLS 


PGVEL 

Q9KNW4 in FASTA format

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