NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC BAA-125 / C-125 / DSM 18197 / FERM 7344 / JCM 9153;
DOI=10.1093/nar/28.21.4317; PubMed=11058132 [NCBI, ExPASy, EBI, Israel, Japan]
Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K.;
"Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis.";
Nucleic Acids Res. 28:4317-4331(2000).

Comments

FUNCTION: Reduction of activated sulfate into sulfite.
CATALYTIC ACTIVITY: Adenosine 3',5'-bisphosphate + sulfite + thioredoxin disulfide = 3'-phosphoadenylyl sulfate + thioredoxin.
PATHWAY: Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 3/3 .
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
SIMILARITY: Belongs to the PAPS reductase family. CysH subfamily.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

BA000004; BAB05205.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

F83835; F83835.

RefSeq

NP_242352.1; -.

3D structure databases

HSSP

P17854; 1SUR. [HSSP ENTRY / PDB]

ModBase

Q9KCT3.

Enzyme and pathway databases

BioCyc

BHAL272558:BH1486-MON; -.

Ontologies

GO:0005737;	Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0004604;	Molecular function: phosphoadenylyl-sulfate reductase (thioredoxin) activity (inferred from electronic annotation from HAMAP).
GO:0019379;	Biological process: sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_00063; -; 1.
PBIL [Tree]

InterPro

IPR011798; APS_reductase.
IPR004511; CysH.
IPR002500; PAPS_reduct.
IPR014729; Rossmann-like_a/b/a_fold.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.50.620; Rossmann-like_a/b/a_fold; 1.

Pfam

PF01507; PAPS_reduct; 1.
Pfam graphical view of domain structure.

TIGRFAMs

TIGR02055; APS_reductase; 1.
TIGR00434; cysH; 1.

BLOCKS

Q9KCT3.

Genome annotation databases

890994; -.

BA000004_GR; BH1486.

bha:BH1486; -.

fig|272558.1.peg.1486; -.

Phylogenomic databases

HOGENOM

Q9KCT3; -.

Genome annotation databases

CMR

Q9KCT3; BH1486.

Other

ProtoNet

Q9KCT3.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Cytoplasm; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 231`	`231`		`Phosphoadenosine phosphosulfate reductase.`	`PRO_0000100625`

Sequence information

Length: 231 AA [This is the length of the unprocessed precursor]

Molecular weight: 27156 Da [This is the MW of the unprocessed precursor]

CRC64: 1EC6F64F12A6B81B [This is a checksum on the sequence]

        10         20         30         40         50         60 
MDQSIQVNIN EVNQALERKD SLDVIKWAYK TYGDKLVYAC SMGAEGMVLI DLISKVRPDA 

        70         80         90        100        110        120 
PVIFLDTDFH FSETYELIER VKERYPKLQL KLVKPELTPE EQAETYGDRL WERQPDLCCK 

       130        140        150        160        170        180 
LRKLVPLEKE LAQYDAWMSG LRRDQSPTRT NTQFVNEDRR FGSTKICPLI HWTSEEIWMY 

       190        200        210        220        230 
IELHQLPYND LHDKQYPSIG CEYCTRPVKE GEDERAGRWS NTSKTECGLH Q

Q9KCT3 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools