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[1]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228;
DOI=10.1038/35023079; PubMed=10984043 [NCBI, ExPASy, EBI, Israel, Japan]
Stover C.K.,
Pham X.-Q.T.,
Erwin A.L.,
Mizoguchi S.D.,
Warrener P.,
Hickey M.J.,
Brinkman F.S.L.,
Hufnagle W.O.,
Kowalik D.J.,
Lagrou M.,
Garber R.L.,
Goltry L.,
Tolentino E.,
Westbrock-Wadman S.,
Yuan Y.,
Brody L.L.,
Coulter S.N.,
Folger K.R.,
Kas A., ![]()
Larbig K.,
Lim R.M.,
Smith K.A.,
Spencer D.H.,
Wong G.K.-S.,
Wu Z.,
Paulsen I.T.,
Reizer J.,
Saier M.H. Jr.,
Hancock R.E.W.,
Lory S.,
Olson M.V.;
"Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen.";
Nature 406:959-964(2000).
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- FUNCTION: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
- CATALYTIC ACTIVITY: 3-methyl-2-oxobutanoate + [dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] lipoyllysine = [dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylpropanoyl)dihydrolipoyllysine + CO2.
- COFACTOR: Thiamine pyrophosphate (By similarity).
- SUBUNIT: Heterodimer of an alpha and a beta chain (By similarity).
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Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms.
Distributed under the Creative Commons Attribution-NoDerivs License.
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| Length: 350 AA [This is the length of the unprocessed precursor] |
Molecular weight: 38325 Da [This is the MW of the unprocessed precursor] |
CRC64: D7983A05A9B3EB0A [This is a checksum on the sequence] |
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10 20 30 40 50 60
MNAMNPQHEN AQTVTSMTMI QALRSAMDIM LERDDDVVVF GQDVGYFGGV FRCTEGLQKK
70 80 90 100 110 120
YGTSRVFDAP ISESGIIGAA VGMGAYGLRP VVEIQFADYV YPASDQLISE AARLRYRSAG
130 140 150 160 170 180
DFIVPMTVRM PCGGGIYGGQ THSQSPEAMF TQVCGLRTVM PSNPYDAKGL LIACIENDDP
190 200 210 220 230 240
VIFLEPKRLY NGPFDGHHDR PVTPWSKHPA SQVPDGYYKV PLDKAAIVRP GAALTVLTYG
250 260 270 280 290 300
TMVYVAQAAA DETGLDAEII DLRSLWPLDL ETIVASVKKT GRCVIAHEAT RTCGFGAELM
310 320 330 340 350
SLVQEHCFHH LEAPIERVTG WDTPYPHAQE WAYFPGPARV GAAFKRVMEV
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Q9I1M1 in FASTA format |
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