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UniProtKB/Swiss-Prot entry Q9FYC2


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PAO_ARATH
Primary accession number Q9FYC2
Secondary accession number O04422
Integrated into Swiss-Prot on February 2, 2004
Sequence was last modified on March 1, 2001 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 47)
Name and origin of the protein
Protein name Pheophorbide a oxygenase, chloroplastic [Precursor]
Synonyms Pheide a oxygenase
AtPaO
EC 1.14.12.20
Accelerated cell death 1
Lethal leaf-spot 1 homolog
Lls1
Gene name
Name: PAO
Synonyms: ACD1
OrderedLocusNames: At3g44880
ORFNames: F28D10_70
From
Arabidopsis thaliana (Mouse-ear cress) [TaxID: 3702] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE.
DOI=10.1104/pp.008441; PubMed=12481072 [NCBI, ExPASy, EBI, Israel, Japan]
Gray J., Janick-Buckner D., Buckner B., Close P.S., Johal G.S.;
"Light-dependent death of maize lls1 cells is mediated by mature chloroplasts.";
Plant Physiol. 130:1894-1907(2002).
[2]
NUCLEOTIDE SEQUENCE [MRNA].
STRAIN=cv. Columbia;
DOI=10.1016/S0092-8674(00)80179-8; PubMed=9094711 [NCBI, ExPASy, EBI, Israel, Japan]
Gray J., Close P.S., Briggs S.P., Johal G.S.;
"A novel suppressor of cell death in plants encoded by the Lls1 gene of maize.";
Cell 89:25-31(1997).
[3]
NUCLEOTIDE SEQUENCE.
STRAIN=cv. Columbia;
Yang M., Wardzala E., Gruis D., Johal G.S., Gray J.;
"The Arabidopsis Acd1 gene is an ortholog of the maize Lls1 gene, but is not essential in chlorophyll b deficient plants.";
Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.
[4]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
DOI=10.1038/35048706; PubMed=11130713 [NCBI, ExPASy, EBI, Israel, Japan]
Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B., Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P., Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H., Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A., Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H., Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J., Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B., Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D., de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E., Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G., Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X., Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M., Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B., Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J., Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C., Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y., Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
"Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
Nature 408:820-822(2000).
[5]
CHARACTERIZATION.
DOI=10.1073/pnas.2036571100; PubMed=14657372 [NCBI, ExPASy, EBI, Israel, Japan]
Pruzinska A., Tanner G., Anders I., Roca M., Hortensteiner S.;
"Chlorophyll breakdown: pheophorbide a oxygenase is a Rieske-type iron-sulfur protein, encoded by the accelerated cell death 1 gene.";
Proc. Natl. Acad. Sci. U.S.A. 100:15259-15264(2003).
[6]
FUNCTION.
DOI=10.1093/pcp/pcg172; PubMed=14701922 [NCBI, ExPASy, EBI, Israel, Japan]
Tanaka R., Hirashima M., Satoh S., Tanaka A.;
"The Arabidopsis-accelerated cell death gene ACD1 is involved in oxygenation of pheophorbide a: inhibition of the pheophorbide a oxygenase activity does not lead to the 'Stay-Green' phenotype in Arabidopsis.";
Plant Cell Physiol. 44:1266-1274(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AY093092; AAM13091.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
U77347; AAC49679.1; ALT_FRAME; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY344061; AAR05797.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AL391254; CAC03538.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T51785; T51785.
RefSeq NP_190074.1; -.
UniGene At.21728
3D structure databases
ModBase Q9FYC2.
Enzyme and pathway databases
BioCyc MetaCyc:AT3G44880-MON; -.
Organism-specific databases
TAIR At3g44880; -.
Gene expression databases
ArrayExpress Q9FYC2; -.
GermOnline AT3G44880; Arabidopsis thaliana.
Family and domain databases
InterPro IPR013626; PaO.
IPR005806; Rieske_reg.
Graphical view of domain structure.
Gene3D G3DSA:2.102.10.10; Rieske_reg; 1.
Pfam PF08417; PaO; 1.
PF00355; Rieske; 1.
Pfam graphical view of domain structure.
PROSITE PS51296; RIESKE; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q9FYC2.
Genome annotation databases
GeneID 823622; -.
GenomeReviews BA000014_GR; AT3G44880.
KEGG ath:AT3G44880; -.
NMPDR fig|3702.1.peg.15696; -.
Other
ProtoNet Q9FYC2.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
2Fe-2S; Chlorophyll catabolism; Chloroplast; Complete proteome; Iron; Iron-sulfur; Membrane; Metal-binding; NADP; Oxidoreductase; Plastid; Plastid inner membrane; Transit peptide.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
TRANSIT   1    49  49     Chloroplast (Potential). 
CHAIN   50   537  488     Pheophorbide a oxygenase, chloroplastic. PRO_0000021999
DOMAIN   88   200  113     Rieske. 
METAL   130   130        Iron-sulfur (2Fe-2S) (By similarity). 
METAL   132   132        Iron-sulfur (2Fe-2S) (via pros nitrogen) (By similarity). 
METAL   150   150        Iron-sulfur (2Fe-2S) (By similarity). 
METAL   153   153        Iron-sulfur (2Fe-2S) (via pros nitrogen) (By similarity). 
CONFLICT   98    98        D -> V (in Ref. 2 and 3). 
Sequence information
Length: 537 AA [This is the length of the unprocessed precursor] Molecular weight: 60756 Da [This is the MW of the unprocessed precursor] CRC64: 61C86A08A00D8940 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSVVLLSSTS ATITKSQSKK IPFLSPTTKF PLKVSISPSR SKLFHNPLRV AAPPSVPTSD 

        70         80         90        100        110        120 
STEEKRIEEE YGGDKEEEGS EFKWRDHWYP VSLVEDLDPN VPTPFQLLGR DLVLWFDRND 

       130        140        150        160        170        180 
QKWAAFDDLC PHRLAPLSEG RLDENGHLQC SYHGWSFGGC GSCTRIPQAA TSGPEARAVK 

       190        200        210        220        230        240 
SPRACAIKFP TMVSQGLLFV WPDENGWDRA NSIEPPRLPD DFDKPEFSTV TIQRDLFYGY 

       250        260        270        280        290        300 
DTLMENVSDP SHIDFAHHKV TGRRDRAKPL PFKVESSGPW GFQGANDDSP RITAKFVAPC 

       310        320        330        340        350        360 
YSMNKIELDA KLPIVGNQKW VIWICSFNIP MAPGKTRSIV CSARNFFQFS VPGPAWWQVV 

       370        380        390        400        410        420 
PRWYEHWTSN LVYDGDMIVL QGQEKVFLAK SMESPDYDVN KQYTKLTFTP TQADRFVLAF 

       430        440        450        460        470        480 
RNWLRRHGKS QPEWFGSTPS NQPLPSTVLT KRQMLDRFDQ HTQVCSSCKG AYNSFQILKK 

       490        500        510        520        530 
FLVGATVFWA ATAGVPSDVQ IRLVLAGLSL ISAASAYALH EQEKNFVFRD YVHSEIE 

Q9FYC2 in FASTA format

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View entry in raw text format (no links)
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