ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry Q9FLB5

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name LAC12_ARATH
Primary accession number Q9FLB5
Secondary accession numbers None
Integrated into Swiss-Prot on April 3, 2007
Sequence was last modified on March 1, 2001 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 40)
Name and origin of the protein
Protein name Laccase-12 [Precursor]
Synonyms EC 1.10.3.2
Benzenediol:oxygen oxidoreductase 12
Urishiol oxidase 12
Diphenol oxidase 12
Gene name
Name: LAC12
OrderedLocusNames: At5g05390
ORFNames: K18I23.20
From
Arabidopsis thaliana (Mouse-ear cress) [TaxID: 3702] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis.
Protein existence 2: Evidence at transcript level;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
DOI=10.1093/dnares/5.2.131; PubMed=9679202 [NCBI, ExPASy, EBI, Israel, Japan]
Kaneko T., Kotani H., Nakamura Y., Sato S., Asamizu E., Miyajima N., Tabata S.;
"Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence features of the regions of 1,381,565 bp covered by twenty one physically assigned P1 and TAC clones.";
DNA Res. 5:131-145(1998).
[2]
 TISSUE SPECIFICITY.
DOI=10.1007/s00425-004-1472-6; PubMed=15940465 [NCBI, ExPASy, EBI, Israel, Japan]
McCaig B.C., Meagher R.B., Dean J.F.D.;
"Gene structure and molecular analysis of the laccase-like multicopper oxidase (LMCO) gene family in Arabidopsis thaliana.";
Planta 221:619-636(2005).
[3]
 TISSUE SPECIFICITY.
DOI=10.1093/jxb/erl022; PubMed=16804053 [NCBI, ExPASy, EBI, Israel, Japan]
Cai X., Davis E.J., Ballif J., Liang M., Bushman E., Haroldsen V., Torabinejad J., Wu Y.;
"Mutant identification and characterization of the laccase gene family in Arabidopsis.";
J. Exp. Bot. 57:2563-2569(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AB010692; BAB09982.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_196158.1; -.
UniGene At.54730
3D structure databases
HSSP Q9Y780; 1HFU. [HSSP ENTRY / PDB]
ModBase Q9FLB5.
Organism-specific databases
TAIR At5g05390; -.
Ontologies
GO
GO:0008471; Molecular function: laccase activity (inferred from electronic annotation from EC).
QuickGo view.
Family and domain databases
InterPro IPR001117; Cu-oxidase.
IPR011706; Cu-oxidase_2.
IPR011707; Cu-oxidase_3.
IPR002355; Cu_oxidase_Cu_BS.
IPR008972; Cupredoxin.
IPR017761; Laccase.
Graphical view of domain structure.
Gene3D G3DSA:2.60.40.420; Cupredoxin; 3.
Pfam PF00394; Cu-oxidase; 1.
PF07731; Cu-oxidase_2; 1.
PF07732; Cu-oxidase_3; 1.
Pfam graphical view of domain structure.
PROSITE PS00079; MULTICOPPER_OXIDASE1; 1.
PS00080; MULTICOPPER_OXIDASE2; 1.
BLOCKS Q9FLB5.
Genome annotation databases
GeneID 830421; -.
GenomeReviews BA000015_GR; AT5G05390.
KEGG ath:AT5G05390; -.
NMPDR fig|3702.1.peg.22645; -.
Other
ProtoNet Q9FLB5.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Apoplast; Complete proteome; Copper; Glycoprotein; Lignin degradation; Metal-binding; Oxidoreductase; Repeat; Secreted; Signal.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
SIGNAL   1    24  24     Potential. 
CHAIN   25   565  541     Laccase-12. PRO_0000283640
DOMAIN   32   148  117     Plastocyanin-like 1. 
DOMAIN   158   310  153     Plastocyanin-like 2. 
DOMAIN   413   549  137     Plastocyanin-like 3. 
METAL   82    82        Copper 1 (type 2) (By similarity). 
METAL   84    84        Copper 2 (type 3) (By similarity). 
METAL   127   127        Copper 2 (type 3) (By similarity). 
METAL   129   129        Copper 3 (type 3) (By similarity). 
METAL   466   466        Copper 4 (type 1) (By similarity). 
METAL   469   469        Copper 1 (type 2) (By similarity). 
METAL   471   471        Copper 3 (type 3) (By similarity). 
METAL   528   528        Copper 3 (type 3) (By similarity). 
METAL   529   529        Copper 4 (type 1) (By similarity). 
METAL   530   530        Copper 2 (type 3) (By similarity). 
METAL   534   534        Copper 4 (type 1) (By similarity). 
CARBOHYD   78    78        N-linked (GlcNAc...) (Potential). 
CARBOHYD   187   187        N-linked (GlcNAc...) (Potential). 
CARBOHYD   203   203        N-linked (GlcNAc...) (Potential). 
CARBOHYD   298   298        N-linked (GlcNAc...) (Potential). 
CARBOHYD   325   325        N-linked (GlcNAc...) (Potential). 
CARBOHYD   377   377        N-linked (GlcNAc...) (Potential). 
CARBOHYD   387   387        N-linked (GlcNAc...) (Potential). 
CARBOHYD   395   395        N-linked (GlcNAc...) (Potential). 
CARBOHYD   428   428        N-linked (GlcNAc...) (Potential). 
Sequence information
Length: 565 AA [This is the length of the unprocessed precursor] Molecular weight: 62734 Da [This is the MW of the unprocessed precursor] CRC64: 15DA9DDD5CA8932E [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MTTVHTFSIL LFFCSLFSAS LIIAKVQHHD FVIQETPVKR LCKTRNAITV NGMFPGPTLE 

        70         80         90        100        110        120 
VNNGDTLEVK VHNRARYNIT IHWHGVRQIR TGWADGPEFV TQCPIRPGKS YTYRFTIQGQ 

       130        140        150        160        170        180 
EGTLWWHAHS SWLRATVYGA LIIHPTPGSS FPFPKPDRQT ALMLGEWWNA NPVDVINQAT 

       190        200        210        220        230        240 
RTGAAPNISD AYTINGQPGD LYNCSTKETV VVPINSGETS LLRVINAALN QPLFFTVANH 

       250        260        270        280        290        300 
KLTVVGADAS YLKPFTTKVL MLGPGQTTDV LLTADQPPKR YYIAARAYQS AQNAPFDNTT 

       310        320        330        340        350        360 
TTAILQYKKT TTTSKPIMPV LPAFNDTNTV TSFSRKFKSL RNVVVPKTID DNLFFTIGLG 

       370        380        390        400        410        420 
LDNCPKKFPK SRCQGLNGTR FTASMNNVSF VLPSNFSLLQ AHSNGIPGVF TTDFPSKPPV 

       430        440        450        460        470        480 
KFDYTGNNIS RALFQPVKGT KLYKLKYGSR VQVVLQDTNI VTSENHPIHL HGYDFYIVGE 

       490        500        510        520        530        540 
GFGNFNPKKD TSKFNLVDPP LRNTVAVPVN GWAVIRFVAD NPGVWLMHCH LDVHIKWGLA 

       550        560 
MAFLVDNGVG ELETLEAPPH DLPIC
Q9FLB5 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA) 		Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Hosted by kr flag YPRC Korea Mirror sites: Australia Brazil Canada China Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!