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UniProtKB/Swiss-Prot entry Q9D826


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name SOX_MOUSE
Primary accession number Q9D826
Secondary accession number O55223
Integrated into Swiss-Prot on January 23, 2002
Sequence was last modified on June 1, 2001 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 56)
Name and origin of the protein
Protein name Peroxisomal sarcosine oxidase
Synonyms PSO
EC 1.5.3.1
EC 1.5.3.7
L-pipecolate oxidase
L-pipecolic acid oxidase
Gene name
Name: Pipox
Synonyms: Pso
From
Mus musculus (Mouse) [TaxID: 10090] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Embryo;
DOI=10.1006/geno.1997.5050; PubMed=9441754 [NCBI, ExPASy, EBI, Israel, Japan]
Herbst R., Barton J.L., Nicklin M.J.H.;
"A mammalian homolog of the bacterial monomeric sarcosine oxidases maps to mouse chromosome 11, close to Cryba1.";
Genomics 46:480-482(1997).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=C57BL/6J;
TISSUE=Small intestine;
DOI=10.1126/science.1112014; PubMed=16141072 [NCBI, ExPASy, EBI, Israel, Japan]
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J., Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
"The transcriptional landscape of the mammalian genome.";
Science 309:1559-1563(2005).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Kidney;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
U94700; AAC39948.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AK008555; BAB25741.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BC013525; AAH13525.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_032978.2; -.
UniGene Mm.8543
3D structure databases
HSSP P40859; 1EL5. [HSSP ENTRY / PDB]
ModBase Q9D826.
Organism-specific databases
MGI MGI:1197006; Pipox.
Gene expression databases
ArrayExpress Q9D826; -.
CleanEx MM_PIPOX; -.
GermOnline ENSMUSG00000017453; Mus musculus.
Ontologies
GO
GO:0005777; Cellular component: peroxisome (inferred from direct assay from HGNC).
QuickGo view.
Family and domain databases
InterPro IPR006076; FAD-dep_OxRdtase.
IPR006281; SoxA_mon.
Graphical view of domain structure.
Pfam PF01266; DAO; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR01377; soxA_mon; 1.
BLOCKS Q9D826.
Genome annotation databases
Ensembl ENSMUSG00000017453; Mus musculus. [Contig view]
GeneID 19193; -.
KEGG mmu:19193; -.
Phylogenomic databases
HOGENOM Q9D826; -.
HOVERGEN Q9D826; -.
Other
SOURCE Pipox; Mus musculus.
ProtoNet Q9D826.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
FAD; Flavoprotein; Oxidoreductase; Peroxisome.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   390  390     Peroxisomal sarcosine oxidase. PRO_0000213774
NP_BIND   9    39  31     FAD (Potential). 
MOTIF   388   390  3     Microbody targeting signal (Potential). 
MOD_RES   319   319        S-8alpha-FAD cysteine (Probable). 
CONFLICT   164   164        Q -> H (in Ref. 1; AAC39948). 
CONFLICT   333   333        C -> W (in Ref. 1; AAC39948). 
CONFLICT   352   352        K -> T (in Ref. 1; AAC39948). 
Sequence information
Length: 390 AA [This is the length of the unprocessed precursor] Molecular weight: 43847 Da [This is the MW of the unprocessed precursor] CRC64: 0C33A96A24731EE0 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MAAQTDFWDA IVIGAGIQGC FTAYHLAKHS KSVLLLEQFF LPHSRGSSHG QSRIIRKAYP 

        70         80         90        100        110        120 
EDFYTMMMKE CYQTWAQLER EAGTQLHRQT ELLLLGTKEN PGLKTIQATL SRQGIDHEYL 

       130        140        150        160        170        180 
SSVDLKQRFP NIRFTRGEVG LLDKTGGVLY ADKALRALQH IICQLGGTVC DGEKVVEIRP 

       190        200        210        220        230        240 
GLPVTVKTTL KSYQANSLVI TAGPWTNRLL HPLGIELPLQ TLRINVCYWR EKVPGSYGVS 

       250        260        270        280        290        300 
QAFPCILGLD LAPHHIYGLP ASEYPGLMKI CYHHGDNVDP EERDCPKTFS DIQDVQILCH 

       310        320        330        340        350        360 
FVRDHLPGLR AEPDIMERCM YTNTPDEHFI LDCHPKYDNI VIGAGFSGHG FKLAPVVGKI 

       370        380        390 
LYELSMKLPP SYDLAPFRMS RFSTLSKAHL 

Q9D826 in FASTA format

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