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UniProtKB/Swiss-Prot entry Q9A3J3

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name DNAE2_CAUCR
Primary accession number Q9A3J3
Secondary accession numbers None
Integrated into Swiss-Prot on July 5, 2005
Sequence was last modified on June 1, 2001 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 42)
Name and origin of the protein
Protein name Error-prone DNA polymerase
Synonym EC 2.7.7.7
Gene name
Name: dnaE2
OrderedLocusNames: CC_3211
From
Caulobacter crescentus (Caulobacter vibrioides) [TaxID: 155892] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Caulobacterales; Caulobacteraceae; Caulobacter.
Protein existence 2: Evidence at transcript level;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 19089 / CB15;
DOI=10.1073/pnas.061029298; PubMed=11259647 [NCBI, ExPASy, EBI, Israel, Japan]
Nierman W.C., Feldblyum T.V., Laub M.T., Paulsen I.T., Nelson K.E., Eisen J.A., Heidelberg J.F., Alley M.R.K., Ohta N., Maddock J.R., Potocka I., Nelson W.C., Newton A., Stephens C., Phadke N.D., Ely B., DeBoy R.T., Dodson R.J., Durkin A.S., Gwinn M.L., Haft D.H., Kolonay J.F., Smit J., Craven M.B., Khouri H.M., Shetty J., Berry K.J., Utterback T.R., Tran K., Wolf A.M., Vamathevan J.J., Ermolaeva M.D., White O., Salzberg S.L., Venter J.C., Shapiro L., Fraser C.M.;
"Complete genome sequence of Caulobacter crescentus.";
Proc. Natl. Acad. Sci. U.S.A. 98:4136-4141(2001).
[2]
 FUNCTION.
STRAIN=CB15N / NA1000;
DOI=10.1093/nar/gki551; PubMed=15886391 [NCBI, ExPASy, EBI, Israel, Japan]
Galhardo R.S., Rocha R.P., Marques M.V., Menck C.F.M.;
"An SOS-regulated operon involved in damage-inducible mutagenesis in Caulobacter crescentus.";
Nucleic Acids Res. 33:2603-2614(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE005673; AAK25173.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR A87647; A87647.
RefSeq NP_422005.1; -.
3D structure databases
ModBase Q9A3J3.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0008408; Molecular function: 3'-5' exonuclease activity (inferred from electronic annotation from InterPro).
GO:0003677; Molecular function: DNA binding (inferred from electronic annotation from InterPro).
GO:0003887; Molecular function: DNA-directed DNA polymerase activity (inferred from electronic annotation from HAMAP).
GO:0006260; Biological process: DNA replication (inferred from electronic annotation from InterPro).
GO:0045020; Biological process: error-prone DNA repair (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01902; -; 1.
PBIL [Tree]
InterPro IPR011708; DNA_pol3_alpha.
IPR004365; NA_bd_OB_tRNA-helicase.
IPR004013; PHP_C.
IPR003141; PHP_N.
IPR004805; PolC_alpha.
Graphical view of domain structure.
Pfam PF07733; DNA_pol3_alpha; 1.
PF02811; PHP; 1.
PF01336; tRNA_anti; 1.
Pfam graphical view of domain structure.
SMART SM00481; POLIIIAc; 1.
SMART graphical view of domain structure.
TIGRFAMs TIGR00594; polc; 1.
ProtoNet Q9A3J3.
Genome annotation databases
GeneID 940962; -.
GenomeReviews AE005673_GR; CC_3211.
KEGG ccr:CC_3211; -.
NMPDR fig|190650.1.peg.3185; -.
TIGR CC_3211; -.
Phylogenomic databases
HOGENOM Q9A3J3; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; DNA damage; DNA repair; DNA replication; DNA-directed DNA polymerase; Nucleotidyltransferase; Transferase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   1083  1083     Error-prone DNA polymerase. PRO_0000103375
Sequence information
Length: 1083 AA [This is the length of the unprocessed precursor] Molecular weight: 120800 Da [This is the MW of the unprocessed precursor] CRC64: 124E5F216A555E64 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MRPPVYAELQ ATTNFSFLRG ASHAEELALT AEALGLTAIG IVDRNSLAGV VRAWTAAKRR 

        70         80         90        100        110        120 
SIRVLTGCRL DFMDGAPSLL CYPTDREAFG RLTRLLTIGQ LRAEKGECHL TWRDFLDHSE 

       130        140        150        160        170        180 
GQLGLIVPPR VLDDSFEQHL TRMAGDLRGR SWLAASRAYA ARDLQRLARL ESLGRTSGAP 

       190        200        210        220        230        240 
IVATNDVLYH GPERRPLQDV ISCVREHCAI QEAGFRLEAN AERHIKSPEE MARLFDRWPR 

       250        260        270        280        290        300 
AVERTVEIVE RIGFDLKDIR EQYPDEPVPP GKTAMQHLTD LTWKGAAWRY PNGVSPKVTA 

       310        320        330        340        350        360 
QIQEELRLIE KMDYPNYFIT VHDIVREARS MGILCQGRGS AANSSVCFCL GVTAIDPTEH 

       370        380        390        400        410        420 
RLLFTRFISE NRGEPPDIDV DFEHDRREEV MQYVFQRYGR AYAAICGTVI HYRPRSAIRD 

       430        440        450        460        470        480 
VGKALGLTED VTSLLAGTVW GSWGDGLPED HLRNAGLDPK APEIARAVGL ANDLIGFPRH 

       490        500        510        520        530        540 
LSQHVGGFVL TKRRLDETVP IGKAAMKDRT FIEWDKDDID SLGLMKVDIL ALGMLHAIQR 

       550        560        570        580        590        600 
AMTMLREDHG QDWLKDLADI PKEVPGVYDM LCAADSVGVF QVESRAQMSM LPRLRPREFY 

       610        620        630        640        650        660 
DLVIQVAIVR PGPIQGDMVH PYLKRRNKEE PVDWPKPSPE HGPPDELQEI LGKTFGVPLF 

       670        680        690        700        710        720 
QEQAMSLAIE AAKFTPDEAD GLRKAMATFR NLGSPDAYRN KFIEGMVGRG YERAFAERCF 

       730        740        750        760        770        780 
KQIEGFSHYG FPESHAASFA KLVYVSAWIK WAWPDVFCAA LINAQPMGFY QPAQLVRDAR 

       790        800        810        820        830        840 
EHGVEVLPPD ILTSDWDCTL APISTGFRPP RVRHDKVACQ ETRPRWKAVR LGFRQIKGLR 

       850        860        870        880        890        900 
ETLDIPPLLK ARGEGARTPA EFAQGGVPQK ALELLAEADA FASVGLSRRE ALWAVKGLKG 

       910        920        930        940        950        960 
EHKAPVQAPL LAGLPLFEER VALPAMAATQ EVAEDYRTTS LSLKAHPIGF YRSMLAARGV 

       970        980        990       1000       1010       1020 
VPAERLLSLK DGARVSVAGL VLIRQRPGTA KGVVFVTLED ETGVANAVVW KDRFDAARNV 

      1030       1040       1050       1060       1070       1080 
VMTASFLIVH GRVQRADNVI HVVAERFTDL SAELSSLRDE PGAPAPRIRQ KVSGRLLRSR 


DFH
Q9A3J3 in FASTA format

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