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UniProtKB/Swiss-Prot entry Q9A2X6


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PROA_CAUCR
Primary accession number Q9A2X6
Secondary accession numbers None
Integrated into Swiss-Prot on June 6, 2002
Sequence was last modified on June 1, 2001 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 52)
Name and origin of the protein
Protein name Gamma-glutamyl phosphate reductase
Synonyms GPR
EC 1.2.1.41
Glutamate-5-semialdehyde dehydrogenase
Glutamyl-gamma-semialdehyde dehydrogenase
GSA dehydrogenase
Gene name
Name: proA
OrderedLocusNames: CC_3430
From
Caulobacter crescentus (Caulobacter vibrioides) [TaxID: 155892] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Caulobacterales; Caulobacteraceae; Caulobacter.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 19089 / CB15;
DOI=10.1073/pnas.061029298; PubMed=11259647 [NCBI, ExPASy, EBI, Israel, Japan]
Nierman W.C., Feldblyum T.V., Laub M.T., Paulsen I.T., Nelson K.E., Eisen J.A., Heidelberg J.F., Alley M.R.K., Ohta N., Maddock J.R., Potocka I., Nelson W.C., Newton A., Stephens C., Phadke N.D., Ely B., DeBoy R.T., Dodson R.J., Durkin A.S., Gwinn M.L., Haft D.H., Kolonay J.F., Smit J., Craven M.B., Khouri H.M., Shetty J., Berry K.J., Utterback T.R., Tran K., Wolf A.M., Vamathevan J.J., Ermolaeva M.D., White O., Salzberg S.L., Venter J.C., Shapiro L., Fraser C.M.;
"Complete genome sequence of Caulobacter crescentus.";
Proc. Natl. Acad. Sci. U.S.A. 98:4136-4141(2001).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE005673; AAK25392.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR D87674; D87674.
RefSeq NP_422224.1; -.
3D structure databases
HSSP Q9WYC9; 1O20. [HSSP ENTRY / PDB]
ModBase Q9A2X6.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0004350; Molecular function: glutamate-5-semialdehyde dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0006561; Biological process: proline biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00412; -; 1.
PBIL [Tree]
InterPro IPR016163; Ald_DHase_C.
IPR016162; Ald_DHase_N.
IPR000965; Gglut_pp_reduct.
IPR012134; Glu-5-SA_DHase.
Graphical view of domain structure.
Gene3D G3DSA:3.40.309.10; Aldehyde_dehydrogenase_C; 1.
G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1.
PANTHER PTHR11063:SF1; GSA_DH; 1.
PIRSF PIRSF000151; GPR; 1.
TIGRFAMs TIGR00407; proA; 1.
PROSITE PS01223; PROA; 1.
BLOCKS Q9A2X6.
Genome annotation databases
GeneID 940829; -.
GenomeReviews AE005673_GR; CC_3430.
KEGG ccr:CC_3430; -.
NMPDR fig|190650.1.peg.3404; -.
TIGR CC_3430; -.
Phylogenomic databases
HOGENOM Q9A2X6; -.
Other
ProtoNet Q9A2X6.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Complete proteome; Cytoplasm; NADP; Oxidoreductase; Proline biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   413  413     Gamma-glutamyl phosphate reductase. PRO_0000189711
Sequence information
Length: 413 AA [This is the length of the unprocessed precursor] Molecular weight: 42493 Da [This is the MW of the unprocessed precursor] CRC64: 01D77D46F6EA38DC [This is a checksum on the sequence]
        10         20         30         40         50         60 
MAGMGRTARE GARALRLATP EQRTAAIQAM AVAIREDADA ILTANAKDLA RAEANGVSGP 

        70         80         90        100        110        120 
MLDRLALDAA RLEGVAAGVE AVAAVPDPVG VATSRWTRPN GLDIARVRTP IGVIAMIYES 

       130        140        150        160        170        180 
RPNVTADAAA LCVRSGNAVI LRGGSECIHS NLAIHAAIAR GLQKAGLPTA AVQAVKTPDR 

       190        200        210        220        230        240 
AAVGMILAGL DRTIDLIIPR GGKSLVARVQ AEARAPVLGH LEGLNHVFVH AAADLKKAVE 

       250        260        270        280        290        300 
VVVNAKLRRV SVCGSAETLL IDQAAADKLL PPIADALIKA GCELRGDAAA RAIEPTMKKA 

       310        320        330        340        350        360 
TVEDWTTEYL APILSVAVVD GVAGAARHIA SYGSGHTDAI ITEDAAAAEA FIAEVDSAIV 

       370        380        390        400        410 
LVNASTQFAD GGEFGFGAEI GIATDKLHAR GPVGAEQLTT FKYVVRGTGQ TRP 

Q9A2X6 in FASTA format

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