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UniProtKB/Swiss-Prot entry Q99YI8


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name GLPO_STRP1
Primary accession number Q99YI8
Secondary accession number Q48XC7
Integrated into Swiss-Prot on September 26, 2001
Sequence was last modified on June 1, 2001 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 45)
Name and origin of the protein
Protein name Alpha-glycerophosphate oxidase
Synonyms EC 1.1.3.21
Glycerol-3-phosphate oxidase
Gene name
Name: glpO
OrderedLocusNames: SPy_1683, M5005_Spy1380
From
Streptococcus pyogenes serotype M1 [TaxID: 301447] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Lactobacillales; Streptococcaceae; Streptococcus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 700294 / SF370 / Serotype M1;
DOI=10.1073/pnas.071559398; PubMed=11296296 [NCBI, ExPASy, EBI, Israel, Japan]
Ferretti J.J., McShan W.M., Ajdic D.J., Savic D.J., Savic G., Lyon K., Primeaux C., Sezate S., Suvorov A.N., Kenton S., Lai H.S., Lin S.P., Qian Y., Jia H.G., Najar F.Z., Ren Q., Zhu H., Song L., White J., Yuan X., Clifton S.W., Roe B.A., McLaughlin R.E.;
"Complete genome sequence of an M1 strain of Streptococcus pyogenes.";
Proc. Natl. Acad. Sci. U.S.A. 98:4658-4663(2001).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC BAA-947 / MGAS5005 / Serotype M1;
DOI=10.1086/432514; PubMed=16088826 [NCBI, ExPASy, EBI, Israel, Japan]
Sumby P., Porcella S.F., Madrigal A.G., Barbian K.D., Virtaneva K., Ricklefs S.M., Sturdevant D.E., Graham M.R., Vuopio-Varkila J., Hoe N.P., Musser J.M.;
"Evolutionary origin and emergence of a highly successful clone of serotype M1 group A Streptococcus involved multiple horizontal gene transfer events.";
J. Infect. Dis. 192:771-782(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE004092; AAK34439.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
CP000017; AAZ51998.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_269718.1; -.
YP_282743.1; -.
3D structure databases
ModBase Q99YI8.
Enzyme and pathway databases
BioCyc SPYO160490:SPY1683-MON; -.
SPYO293653:M5005_SPY1380-MON; -.
Family and domain databases
InterPro IPR000447; FAD-dep_Gly3P_DHase.
IPR006076; FAD-dep_OxRdtase.
Graphical view of domain structure.
Pfam PF01266; DAO; 1.
Pfam graphical view of domain structure.
PRINTS PR01001; FADG3PDH.
PROSITE PS00977; FAD_G3PDH_1; 1.
PS00978; FAD_G3PDH_2; FALSE_NEG.
BLOCKS Q99YI8.
Genome annotation databases
GeneID 3571534; -.
901929; -.
GenomeReviews CP000017_GR; M5005_Spy1380.
AE004092_GR; SPy_1683.
KEGG spy:SPy_1683; -.
spz:M5005_Spy_1380; -.
Phylogenomic databases
HOGENOM Q99YI8; -.
Genome annotation databases
CMR Q99YI8; SPy_1683.
Other
ProtoNet Q99YI8.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; FAD; Flavoprotein; Glycerol metabolism; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom  To Length Description FTId
CHAIN   1   612  612     Alpha-glycerophosphate oxidase. PRO_0000126110
NP_BIND   21    49  29     FAD (Potential). 
Sequence information
Length: 612 AA [This is the length of the unprocessed precursor] Molecular weight: 67640 Da [This is the MW of the unprocessed precursor] CRC64: C5016720426C4BB4 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MEFSRETRRL ALQKMQERDL DLLIIGGGIT GAGVALQAAA SGLDTGLIEM QDFAQGTSSR 

        70         80         90        100        110        120 
STKLVHGGLR YLKQFDVEVV SDTVSERAVV QQIAPHIPKP DPMLLPVYDE PGSTFSMFRL 

       130        140        150        160        170        180 
KVAMDLYDLL AGVSNTPAAN KVLTKEEVLK REPDLKQEGL LGGGVYLDFR NNDARLVIEN 

       190        200        210        220        230        240 
IKRANRDGAL IASHVKAEDF LLDDNGKIIG VKARDLLSDQ EIIIKAKLVI NTTGPWSDEI 

       250        260        270        280        290        300 
RQFSHKGQPI HQMRPTKGVH LVVDRQKLPV SQPVYVDTGL NDGRMVFVLP REEKTYFGTT 

       310        320        330        340        350        360 
DTDYTGDLEH PQVTQEDVDY LLGVVNNRFP NANVTIDDIE SSWAGLRPLL SGNSASDYNG 

       370        380        390        400        410        420 
GNSGKVSDDS FDHLVDTVKA YINHEDSREA VEKAIKQVET STSEKELDPS AVSRGSSFER 

       430        440        450        460        470        480 
DENGLFTLAG GKITDYRKMA EGALTGIIQI LKEEFGKSFK LINSKTYPVS GGEINPANVD 

       490        500        510        520        530        540 
SEIEAYAQLG TLSGLSMDDA RYLANLYGSN APKVFALTRQ LTAAEGLSLA ETLSLHYAMD 

       550        560        570        580        590        600 
YEMALKPTDY FLRRTNHLLF MRDSLDALID PVINEMAKHF EWSDQERVAQ EDDLRRVIAD 

       610 
NDLSALKGHQ EG 

Q99YI8 in FASTA format

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