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UniProtKB/Swiss-Prot entry Q99046

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name LAC2_TRAVI
Primary accession number Q99046
Secondary accession numbers None
Integrated into Swiss-Prot on November 1, 1997
Sequence was last modified on November 1, 1996 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 49)
Name and origin of the protein
Protein name Laccase-2 [Precursor]
Synonyms EC 1.10.3.2
Benzenediol:oxygen oxidoreductase 2
Urishiol oxidase 2
Diphenol oxidase 2
Gene name
Name: LCC2
From
Trametes villosa (White-rot fungus) [TaxID: 47662] 
Taxonomy Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes; Polyporales; Trametes.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA].
TISSUE=Mycelium;
PubMed=8975613 [NCBI, ExPASy, EBI, Israel, Japan]
Yaver D.S., Xu F., Golightly E.J., Brown K.M., Brown S.H., Rey M.W., Schneider P., Halkier T., Mondorf K., Dalboge H.;
"Purification, characterization, molecular cloning, and expression of two laccase genes from the white rot basidiomycete Trametes villosa.";
Appl. Environ. Microbiol. 62:834-841(1996).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
L49377; AAC41687.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
3D structure databases
HSSP Q12718; 1GYC. [HSSP ENTRY / PDB]
SMR Q99046; 21-519.
ModBase Q99046.
Ontologies
GO
GO:0008471; Molecular function: laccase activity (inferred from electronic annotation from EC).
QuickGo view.
Family and domain databases
InterPro IPR001117; Cu-oxidase.
IPR011706; Cu-oxidase_2.
IPR011707; Cu-oxidase_3.
IPR002355; Cu_oxidase_Cu_BS.
IPR008972; Cupredoxin.
Graphical view of domain structure.
Gene3D G3DSA:2.60.40.420; Cupredoxin; 3.
Pfam PF00394; Cu-oxidase; 1.
PF07731; Cu-oxidase_2; 1.
PF07732; Cu-oxidase_3; 1.
Pfam graphical view of domain structure.
PROSITE PS00079; MULTICOPPER_OXIDASE1; 1.
PS00080; MULTICOPPER_OXIDASE2; FALSE_NEG.
BLOCKS Q99046.
Other
ProtoNet Q99046.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Copper; Glycoprotein; Lignin degradation; Metal-binding; Oxidoreductase; Repeat; Secreted; Signal.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
SIGNAL   1    20  20     Potential. 
CHAIN   21   519  499     Laccase-2. PRO_0000002944
DOMAIN   22   147  126     Plastocyanin-like 1. 
DOMAIN   159   301  143     Plastocyanin-like 2. 
DOMAIN   368   490  123     Plastocyanin-like 3. 
METAL   84    84        Copper 1 (type 2) (By similarity). 
METAL   86    86        Copper 2 (type 3) (By similarity). 
METAL   129   129        Copper 2 (type 3) (By similarity). 
METAL   131   131        Copper 3 (type 3) (By similarity). 
METAL   415   415        Copper 4 (type 1) (By similarity). 
METAL   418   418        Copper 1 (type 2) (By similarity). 
METAL   420   420        Copper 3 (type 3) (By similarity). 
METAL   472   472        Copper 3 (type 3) (By similarity). 
METAL   473   473        Copper 4 (type 1) (By similarity). 
METAL   474   474        Copper 2 (type 3) (By similarity). 
METAL   478   478        Copper 4 (type 1) (By similarity). 
CARBOHYD   74    74        N-linked (GlcNAc...) (Potential). 
CARBOHYD   161   161        N-linked (GlcNAc...) (Potential). 
CARBOHYD   228   228        N-linked (GlcNAc...) (Potential). 
CARBOHYD   237   237        N-linked (GlcNAc...) (Potential). 
CARBOHYD   271   271        N-linked (GlcNAc...) (Potential). 
CARBOHYD   353   353        N-linked (GlcNAc...) (Potential). 
CARBOHYD   361   361        N-linked (GlcNAc...) (Potential). 
CARBOHYD   456   456        N-linked (GlcNAc...) (Potential). 
Sequence information
Length: 519 AA [This is the length of the unprocessed precursor] Molecular weight: 55777 Da [This is the MW of the unprocessed precursor] CRC64: DBB4EA526F684740 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MGLQRFSFFV TLALVARSLA AIGPVASLVV ANAPVSPDGF LRDAIVVNGV VPSPLITGKK 

        70         80         90        100        110        120 
GDRFQLNVVD TLTNHSMLKS TSIHWHGFFQ AGTNWAEGPA FVNQCPIASG HSFLYDFHVP 

       130        140        150        160        170        180 
DQAGTFWYHS HLSTQYCDGL RGPFVVYDPK DPHASRYDVD NESTVITLTD WYHTAARLGP 

       190        200        210        220        230        240 
KFPLGADATL INGLGRSAST PTAALAVINV QHGKRYRFRL VSISCDPNYT FSIDGHNLTV 

       250        260        270        280        290        300 
IEVDGINSQP LLVDSIQIFA AQRYSFVLNA NQTVGNYWVR ANPNFGTVGF AGGINSAILR 

       310        320        330        340        350        360 
YQGAPVAEPT TTQTPSVIPL IETNLHPLAR MPVPGSPTPG GVDKALNLAF NFNGTNFFIN 

       370        380        390        400        410        420 
NATFTPPTVP VLLQILSGAQ TAQDLLPAGS VYPLPAHSTI EITLPATALA PGAPHPFHLH 

       430        440        450        460        470        480 
GHAFAVVRSA GSTTYNYNDP IFRDVVSTGT PAAGDNVTIR FQTDNPGPWF LHCHIDFHLD 

       490        500        510 
AGFAIVFAED VADVKAANPV PKAWSDLCPI YDGLSEANQ
Q99046 in FASTA format

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