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UniProtKB/Swiss-Prot entry Q983J4

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name HGD_RHILO
Primary accession number Q983J4
Secondary accession numbers None
Integrated into Swiss-Prot on May 27, 2002
Sequence was last modified on October 1, 2001 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 36)
Name and origin of the protein
Protein name Homogentisate 1,2-dioxygenase
Synonyms EC 1.13.11.5
Homogentisicase
Homogentisate oxygenase
Homogentisic acid oxidase
Gene name
Name: hmgA
OrderedLocusNames: mlr8303
From
Rhizobium loti (Mesorhizobium loti) [TaxID: 381] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Phyllobacteriaceae; Mesorhizobium.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=MAFF303099;
DOI=10.1093/dnares/7.6.331; PubMed=11214968 [NCBI, ExPASy, EBI, Israel, Japan]
Kaneko T., Nakamura Y., Sato S., Asamizu E., Kato T., Sasamoto S., Watanabe A., Idesawa K., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Mochizuki Y., Nakayama S., Nakazaki N., Shimpo S., Sugimoto M., Takeuchi C., Yamada M., Tabata S.;
"Complete genome structure of the nitrogen-fixing symbiotic bacterium Mesorhizobium loti.";
DNA Res. 7:331-338(2000).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BA000012; BAB53887.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_108426.1; -.
3D structure databases
ModBase Q983J4.
Ontologies
GO
GO:0004411; Molecular function: homogentisate 1,2-dioxygenase activity (inferred from electronic annotation from HAMAP).
GO:0005506; Molecular function: iron ion binding (inferred from electronic annotation from HAMAP).
GO:0006559; Biological process: L-phenylalanine catabolic process (inferred from electronic annotation from HAMAP).
GO:0006572; Biological process: tyrosine catabolic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00334; -; 1.
PBIL [Tree]
InterPro IPR002110; ANK.
IPR005708; Homogentis_dOase.
Graphical view of domain structure.
PANTHER PTHR11056; Homogentis_dOase; 1.
Pfam PF04209; HgmA; 1.
Pfam graphical view of domain structure.
PRINTS PR01415; ANKYRIN.
TIGRFAMs TIGR01015; hmgA; 1.
BLOCKS Q983J4.
Genome annotation databases
GeneID 1231078; -.
GenomeReviews BA000012_GR; mlr8303.
KEGG mlo:mlr8303; -.
NMPDR fig|266835.1.peg.6525; -.
Phylogenomic databases
HOGENOM Q983J4; -.
Genome annotation databases
CMR Q983J4; mlr8303.
Other
ProtoNet Q983J4.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Dioxygenase; Iron; Metal-binding; Oxidoreductase; Phenylalanine catabolism; Tyrosine catabolism.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   457  457     Homogentisate 1,2-dioxygenase. PRO_0000220253
METAL   351   351        Iron (By similarity). 
METAL   357   357        Iron (By similarity). 
METAL   387   387        Iron (By similarity). 
Sequence information
Length: 457 AA [This is the length of the unprocessed precursor] Molecular weight: 51046 Da [This is the MW of the unprocessed precursor] CRC64: 6A20B69E9A2B2BD1 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MVNTGRLGFV KLGAGIKEDR MAFSYMPGFG NDFETETLPG SLPQGRNSPQ RPAYGLYAEQ 

        70         80         90        100        110        120 
LSGSPFTAPR GTNERSWLYR IRPSVKHTGR FKAASYPLWK TAPNVGDHEL ALGQYRWNPV 

       130        140        150        160        170        180 
PMPKEPTDFI QGMRSITTAG DVLGQTGMAA HVYVANRSMV DDHFFNADGE LLVVPQVGAL 

       190        200        210        220        230        240 
RFVTEMGVIE LRPGEIAVLP RGLVFKAELV DKDVRGYVCE NYGAKLTLPD RGPIGANCLA 

       250        260        270        280        290        300 
NPRDFKTPCA WFEEKETPCR LIVKWCGNFH VTEIGHSPLD VVAWHGNYAP YKYDLATFSP 

       310        320        330        340        350        360 
VGAILFDHPD PSIFTVLTAP SGEEGTANID FVIFPPRWLV AEDTFRPPWY HRNIMSEFMG 

       370        380        390        400        410        420 
LIHGQYDAKE EGFVPGGISL HNLMLAHGPD APGFEKASRA DLKPVKLDNT MAFMFETRFP 

       430        440        450 
QMLTRYGAEL ETRQDNYIDC WADLKKRFNG TPEGDWS
Q983J4 in FASTA format

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