ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry Q96480

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name P5CS_SOLLC
Primary accession number Q96480
Secondary accession numbers None
Integrated into Swiss-Prot on May 30, 2000
Sequence was last modified on February 1, 1997 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 62)
Name and origin of the protein
Protein name Delta-1-pyrroline-5-carboxylate synthetase
Synonym P5CS
Includes Glutamate 5-kinase
     (GK)
     (EC 2.7.2.11)
     (Gamma-glutamyl kinase)
Gamma-glutamyl phosphate reductase
     (GPR)
     (EC 1.2.1.41)
     (Glutamate-5-semialdehyde dehydrogenase)
     (Glutamyl-gamma-semialdehyde dehydrogenase)
Gene name
Name: PRO2
From
Solanum lycopersicum (Tomato) (Lycopersicon esculentum) [TaxID: 4081] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum; Lycopersicon.
Protein existence 2: Evidence at transcript level;
References
[1]
 NUCLEOTIDE SEQUENCE [MRNA].
STRAIN=cv. Ailsa Craig;
Maggio A., Garcia-Rios M., Fujita T., Bressan R.A., Joly R.J., Hasegawa M.P., Csonka L.N.;
"Cloning of tomPRO1 and tomPRO2 from Lycopersicon esculentum L.: coexistence of policistronic and monocistronic genes which encode the enzymes catalyzing the first two steps of proline biosynthesis.";
(er) Plant Gene Register PGR96-077.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
U60267; AAB67875.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T07422; T07422.
UniGene Les.20195
3D structure databases
HSSP Q9WYC9; 1O20. [HSSP ENTRY / PDB]
ModBase Q96480.
Family and domain databases
InterPro IPR016163; Ald_DHase_C.
IPR016162; Ald_DHase_N.
IPR001048; Asp/Glu/Uridylate_kinase.
IPR000965; Gglut_pp_reduct.
IPR001057; Glu_5kinase.
IPR005766; P5_carboxy_syn.
IPR005715; ProB.
Graphical view of domain structure.
Gene3D G3DSA:3.40.1160.10; Aa_kinase; 1.
G3DSA:3.40.309.10; Aldehyde_dehydrogenase_C; 1.
G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1.
Pfam PF00696; AA_kinase; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF036429; P5C_syn; 1.
PRINTS PR00474; GLU5KINASE.
TIGRFAMs TIGR01092; P5CS; 1.
TIGR00407; proA; 1.
TIGR01027; proB; 1.
PROSITE PS00902; GLUTAMATE_5_KINASE; 1.
PS01223; PROA; 1.
BLOCKS Q96480.
Other
ProtoNet Q96480.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Kinase; Multifunctional enzyme; NADP; Oxidoreductase; Proline biosynthesis; Transferase.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   717  717     Delta-1-pyrroline-5-carboxylate synthetase. PRO_0000109775
REGION   1   296  296     Glutamate 5-kinase. 
REGION   297   717  421     Gamma-glutamyl phosphate reductase. 
Sequence information
Length: 717 AA [This is the length of the unprocessed precursor] Molecular weight: 77590 Da [This is the MW of the unprocessed precursor] CRC64: 1E206428B69EEBCA [This is a checksum on the sequence] 
        10         20         30         40         50         60 
METVDSTRAF VKNVKRLIVK VGTAVVTRAD GRLALGRLGA LCEQLQELNS QGYEVILVTS 

        70         80         90        100        110        120 
GAVGVGRQRL RYRKLLNSSF LDLQKPQTEL DGKACAAVGQ NGLMALYDSL FSQLDVTSAQ 

       130        140        150        160        170        180 
LLVTDNDFRD PDFRRQLNDT VNSLLSLKVI PIFNENDAIS TRRAPYEDSS GIFWDNDSLA 

       190        200        210        220        230        240 
ALLALELKAD LLVLLSDVDG LYSGPPRDPD SKLIYTYIKE IHERVITFGD KSRVGRGGMT 

       250        260        270        280        290        300 
AKVKAAMYAA YAGIPVVITS GFATDNIIKV LHGERIGTLF HCDANKWASI GETDAREMAV 

       310        320        330        340        350        360 
AARACSRRLQ ALSSQERSKI LQDIADALEA NEKAILAENE ADVVAAQQAG YEKSLISRLA 

       370        380        390        400        410        420 
LNPGKISSLA NSVRVLSNMD EPLGHTLKRT EIADGFILEK SSSPLGVVLI IFESRPDALV 

       430        440        450        460        470        480 
QIASLAVRSG NGLMLKGGKE AKRSNAILHK VITSAIPVSV GERLIGLVTS REEIPELLKL 

       490        500        510        520        530        540 
DDVIDLVIPR GSNKLVSQIK ASTKIPVLGH ADGICHVYVD KSADMDMAKR ITVDAKIDYP 

       550        560        570        580        590        600 
AACNAMETLL VHKDLAQNGG LNDLIVELQT KGVSLYGGPK ASSLLMIPEA RTFRHEYSSL 

       610        620        630        640        650        660 
ACTVEVVEDV YAAIDHIHQH GSAHTDSIIT EDQEVAEVFL RQVDSAAVFH NASTRFSDGF 

       670        680        690        700        710 
RFGLGAEVGI STGRIHARGP VGVEGLLTTK WLARGSGQIV DGDKSIVYSH KDLTQQG
Q96480 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA) 		Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Hosted by kr flag YPRC Korea Mirror sites: Australia Brazil Canada China Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!