[1]	NUCLEOTIDE SEQUENCE [GENOMIC DNA]. STRAIN=P4a; DOI=10.1099/mic.0.26260-0; PubMed=12949179 [NCBI, ExPASy, EBI, Israel, Japan] Hoffmann D., Kleinsteuber S., Mueller R.H., Babel W.; "A transposon encoding the complete 2,4-dichlorophenoxyacetic acid degradation pathway in the alkalitolerant strain Delftia acidovorans P4a."; Microbiology 149:2545-2556(2003).
[2]	NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 101-235. STRAIN=P4a; Hoffmann D., Kleinsteuber S., Mueller R.H., Babel W.; "Development and application of PCR primers for the detection of the tfd genes in Delftia acidovorans P4a involved in the degradation of 2,4-D."; Acta Biotechnol. 21:321-331(2001).
[3]	PROTEIN SEQUENCE OF 1-15. STRAIN=MC1; DOI=10.1099/mic.0.26774-0; PubMed=15073309 [NCBI, ExPASy, EBI, Israel, Japan] Benndorf D., Davidson I., Babel W.; "Regulation of catabolic enzymes during long-term exposure of Delftia acidovorans MC1 to chlorophenoxy herbicides."; Microbiology 150:1005-1014(2004).

Comments

CATALYTIC ACTIVITY: 3-oxoadipate + NAD(P)⁺ = 2-maleylacetate + NAD(P)H.
PATHWAY: Aromatic compound metabolism; 3-chlorocatechol degradation .
SUBUNIT: Homodimer (Probable).
SIMILARITY: Belongs to the iron-containing alcohol dehydrogenase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AY078159; AAK57010.2; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

3D structure databases

ModBase

Q93T12.

Family and domain databases

InterPro

IPR001670; Fe_AlcDHase.
Graphical view of domain structure.

Pfam

PF00465; Fe-ADH; 1.
Pfam graphical view of domain structure.

PROSITE

PS00913; ADH_IRON_1; FALSE_NEG.
PS00060; ADH_IRON_2; FALSE_NEG.

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Aromatic hydrocarbons catabolism; Direct protein sequencing; NAD; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 352`	`352`		`Maleylacetate reductase.`	`PRO_0000087850`

Sequence information

Length: 352 AA [This is the length of the unprocessed precursor]

Molecular weight: 37499 Da [This is the MW of the unprocessed precursor]

CRC64: C72A9D2671FFFAB3 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MNFIHDPLTP RVLFGAGRLQ SLGEELKLLG IRRVLVISTP EQRELANQVA ALIPGSVAGF 

        70         80         90        100        110        120 
FDRATMHVPS QIVDQAASVA RELGVDSYVA PGGGSTIGLA KMLALHSSLP IVAIPTTYAG 

       130        140        150        160        170        180 
SEMTSIYGVT ENELKKTGRD RRVLARTVIY DPELTFGLPT GISVTSGLNA IAHAVEGLYA 

       190        200        210        220        230        240 
PEVNPILAIM AQQGIAALAK SIPTIRSAPT DLEARSQAQY GAWLCGSVLG NVSMALHHKL 

       250        260        270        280        290        300 
CHTLGGTFNL PHAETHTVVL PHALAYNTPA IPRANAWLQE ALATREPAQA LFDLAKSNGA 

       310        320        330        340        350 
PVSLQSIGMK EADLDRACEL VMSAQYPNPR PLEKHAIANL LRRAYLGEPP QP

Q93T12 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools