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UniProtKB/Swiss-Prot entry Q8ZGV9


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name BETB_YERPE
Primary accession number Q8ZGV9
Secondary accession numbers Q0WHN3 Q74W89
Integrated into Swiss-Prot on February 1, 2005
Sequence was last modified on March 1, 2002 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 43)
Name and origin of the protein
Protein name Betaine aldehyde dehydrogenase
Synonyms BADH
EC 1.2.1.8
Gene name
Name: betB
OrderedLocusNames: YPO1166, YP_0993
From
Yersinia pestis [TaxID: 632] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Yersinia.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=CO-92 / Biovar Orientalis;
DOI=10.1038/35097083; PubMed=11586360 [NCBI, ExPASy, EBI, Israel, Japan]
Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G., Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L., Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M., Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T., Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S., Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S., Barrell B.G.;
"Genome sequence of Yersinia pestis, the causative agent of plague.";
Nature 413:523-527(2001).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=91001 / Biovar Mediaevalis;
DOI=10.1093/dnares/11.3.179; PubMed=15368893 [NCBI, ExPASy, EBI, Israel, Japan]
Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D., Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L., Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H., Wang J., Huang P., Yang R.;
"Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans.";
DNA Res. 11:179-197(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AL590842; CAL19830.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AE017042; AAS61244.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR AD0143; AD0143.
RefSeq NP_992367.1; -.
3D structure databases
HSSP P56533; 1A4S. [HSSP ENTRY / PDB]
ModBase Q8ZGV9.
Enzyme and pathway databases
BioCyc YPES214092:YPO1166-MON; -.
YPES229193:YP0993-MON; -.
Ontologies
GO
GO:0008802; Molecular function: betaine-aldehyde dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0019285; Biological process: glycine betaine biosynthetic process from choline (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00804; -; 1.
PBIL [Tree]
InterPro IPR016160; Ald_DHase_CS.
IPR016162; Ald_DHase_N.
IPR015590; Aldehyde_DHase.
IPR011264; Betaine_Ald_DHase.
Graphical view of domain structure.
Gene3D G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1.
PANTHER PTHR11699; Aldehyde_dehyd; 1.
Pfam PF00171; Aldedh; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR01804; BADH; 1.
PROSITE PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PS00687; ALDEHYDE_DEHYDR_GLU; 1.
BLOCKS Q8ZGV9.
Genome annotation databases
GeneID 2764902; -.
GenomeReviews AE017042_GR; YP_0993.
AL590842_GR; YPO1166.
KEGG ype:YPO1166; -.
ypm:YP_0993; -.
Phylogenomic databases
HOGENOM Q8ZGV9; -.
Genome annotation databases
CMR Q8ZGV9; YPO1166.
Other
ProtoNet Q8ZGV9.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   490  490     Betaine aldehyde dehydrogenase. PRO_0000056561
NP_BIND   229   234  6     NAD (By similarity). 
ACT_SITE   252   252        By similarity. 
ACT_SITE   286   286        By similarity. 
Sequence information
Length: 490 AA [This is the length of the unprocessed precursor] Molecular weight: 52596 Da [This is the MW of the unprocessed precursor] CRC64: F44CCA7CEE56F0B9 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSRYGLQKLY INGAYTDSTS GDTFDAVNPA NGECIAQLQA ANAQDVDKAV AAAKQGQPVW 

        70         80         90        100        110        120 
AAMTAMERSR ILRRAVDILR DRNDELAAIE TADTGKPLSE TRSVDIVTGA DVLEYYAGLI 

       130        140        150        160        170        180 
PALEGQQIPL RGSAFVYTRR EPLGVVAGIG AWNYPLQIAL WKSAPALAAG NAMIFKPSEV 

       190        200        210        220        230        240 
TSLTALKLAG IYTEAGLPAG VFNVLTGSGD QVGQMLTEHP GIAKVSFTGG IASGKKVMAN 

       250        260        270        280        290        300 
AAGSTLKDVT MELGGKSPLI IFADADLDKA ADIAMMANFY SSGQVCTNGT RVFVPQALQA 

       310        320        330        340        350        360 
AFEQKIVERV KRIHIGDPSD ERTNFGPLVS FQHRDSVMRY IDSGKREGAT LLIGGYSLTE 

       370        380        390        400        410        420 
GALAHGAYVA PTVFTHCRDD MQIVREEIFG PVMSILSYQS EEEVIRRAND TEYGLAAGVV 

       430        440        450        460        470        480 
TQDLNRAHRV IHQLQAGICW INTWGESAPE MPVGGYKHSG VGRENGISTL EHYTQIKSIQ 

       490 
VELGSFNSVF 

Q8ZGV9 in FASTA format

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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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