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UniProtKB/Swiss-Prot entry Q8Z460


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name CYSH_SALTI
Primary accession number Q8Z460
Secondary accession numbers None
Integrated into Swiss-Prot on July 11, 2002
Sequence was last modified on January 23, 2007 (Sequence version 3)
Annotations were last modified on    July 22, 2008 (Entry version 44)
Name and origin of the protein
Protein name Phosphoadenosine phosphosulfate reductase
Synonyms EC 1.8.4.8
PAPS reductase, thioredoxin dependent
PAdoPS reductase
3'-phosphoadenylylsulfate reductase
PAPS sulfotransferase
Gene name
Name: cysH
OrderedLocusNames: STY3074, t2847
From
Salmonella typhi [TaxID: 601] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Salmonella.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=CT18;
DOI=10.1038/35101607; PubMed=11677608 [NCBI, ExPASy, EBI, Israel, Japan]
Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J., Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M., Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A., Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T., Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A., Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A., Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S., Barrell B.G.;
"Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18.";
Nature 413:848-852(2001).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 700931 / Ty2;
DOI=10.1128/JB.185.7.2330-2337.2003; PubMed=12644504 [NCBI, ExPASy, EBI, Israel, Japan]
Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V., Kodoyianni V., Schwartz D.C., Blattner F.R.;
"Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and CT18.";
J. Bacteriol. 185:2330-2337(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AL627276; CAD06052.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AE014613; AAO70404.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_457335.1; -.
NP_806544.1; -.
3D structure databases
HSSP P17854; 1SUR. [HSSP ENTRY / PDB]
SMR Q8Z460; 2-230.
ModBase Q8Z460.
Enzyme and pathway databases
BioCyc SENT209261:T2847-MON; -.
SENT220341:STY3074-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0004604; Molecular function: phosphoadenylyl-sulfate reductase (thioredoxin) activity (inferred from electronic annotation from HAMAP).
GO:0019379; Biological process: sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00063; -; 1.
PBIL [Tree]
InterPro IPR004511; CysH.
IPR002500; PAPS_reduct.
IPR011800; PAPS_reductase.
IPR014729; Rossmann-like_a/b/a_fold.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.620; Rossmann-like_a/b/a_fold; 1.
Pfam PF01507; PAPS_reduct; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00434; cysH; 1.
TIGR02057; PAPS_reductase; 1.
BLOCKS Q8Z460.
Genome annotation databases
GeneID 1068742; -.
1249374; -.
GenomeReviews AL513382_GR; STY3074.
AE014613_GR; t2847.
KEGG stt:t2847; -.
sty:STY3074; -.
Phylogenomic databases
HOGENOM Q8Z460; -.
Genome annotation databases
CMR Q8Z460; STY3074.
Other
ProtoNet Q8Z460.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
INIT_MET   1     1        Removed (By similarity). 
CHAIN   2   244  243     Phosphoadenosine phosphosulfate reductase. PRO_0000100642
Sequence information
Length: 244 AA [This is the length of the unprocessed precursor] Molecular weight: 27938 Da [This is the MW of the unprocessed precursor] CRC64: 8B08DCF029CE141D [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSQLDLNALN ELPKVDRVLA LAETNAQLET LTAEERVAWA LENLPGEYVL SSSFGIQAAV 

        70         80         90        100        110        120 
SLHLVNQIRP DIPVILTDTG YLFPETYQFI DELTDKLKLN LKVYRAGESP AWQEARYGKL 

       130        140        150        160        170        180 
WEQGVEGIEK YNEINKVEPM NRALKELNAQ TWFAGLRREQ SGSRAHLPVL AIQRGVFKVL 

       190        200        210        220        230        240 
PIIDWDNRTV YQYLQKHGLK YHPLWAQGYL SVGDTHTTRK WEPGMAEEET RFFGLKRECG 


LHEG 

Q8Z460 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

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