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UniProtKB/Swiss-Prot entry Q8WN98

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name MIOX_PIG
Primary accession number Q8WN98
Secondary accession numbers None
Integrated into Swiss-Prot on February 12, 2003
Sequence was last modified on March 1, 2002 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 35)
Name and origin of the protein
Protein name Inositol oxygenase
Synonyms EC 1.13.99.1
Myo-inositol oxygenase
MI oxygenase
Aldehyde reductase-like 6
Gene name
Name: MIOX
Synonyms: ALDRL6
From
Sus scrofa (Pig) [TaxID: 9823] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae; Sus.
Protein existence 1: Evidence at protein level;
References
[1]
 NUCLEOTIDE SEQUENCE [MRNA], AND CHARACTERIZATION.
TISSUE=Kidney;
DOI=10.1042/0264-6021:3600313; PubMed=11716759 [NCBI, ExPASy, EBI, Israel, Japan]
Arner R.J., Prabhu K.S., Thompson J.T., Hildenbrandt G.R., Liken A.D., Reddy C.C.;
"Myo-inositol oxygenase: molecular cloning and expression of a unique enzyme that oxidizes myo-inositol and d-chiro-inositol.";
Biochem. J. 360:313-320(2001).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AF401311; AAL39076.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_999267.1; -.
UniGene Ssc.15816
3D structure databases
SMR Q8WN98; 25-282.
ModBase Q8WN98.
Ontologies
GO
GO:0016234; Cellular component: inclusion body (inferred from direct assay from UniProtKB).
GO:0016701; Molecular function: oxidoreductase activity, acting on single donors with incorporation of molecular oxygen (inferred from direct assay from UniProtKB).
GO:0009992; Biological process: cellular water homeostasis (traceable author statement from UniProtKB).
GO:0019310; Biological process: inositol catabolic process (inferred from direct assay from UniProtKB).
GO:0048016; Biological process: inositol phosphate-mediated signaling (traceable author statement from UniProtKB).
GO:0016044; Biological process: membrane organization and biogenesis (traceable author statement from UniProtKB).
QuickGo view.
Family and domain databases
InterPro IPR007828; DUF706.
Graphical view of domain structure.
PANTHER PTHR12588; DUF706; 1.
Pfam PF05153; DUF706; 1.
Pfam graphical view of domain structure.
BLOCKS Q8WN98.
Genome annotation databases
GeneID 397189; -.
KEGG ssc:397189; -.
Phylogenomic databases
HOVERGEN Q8WN98; -.
Other
ProtoNet Q8WN98.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Cytoplasm; Iron; Metal-binding; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   282  282     Inositol oxygenase. PRO_0000079150
METAL   95    95        Iron 1 (By similarity). 
METAL   120   120        Iron 1 (By similarity). 
METAL   121   121        Iron 1 (By similarity). 
METAL   121   121        Iron 2 (By similarity). 
METAL   191   191        Iron 2 (By similarity). 
METAL   217   217        Iron 2 (By similarity). 
METAL   250   250        Iron 1 (By similarity). 
Sequence information
Length: 282 AA [This is the length of the unprocessed precursor] Molecular weight: 32653 Da [This is the MW of the unprocessed precursor] CRC64: 0B9D4D54A3AE5DE0 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MKDPDPSQVY RPDMDPEAAK DKGSFRNYTS GPLLDRVFRT YKLMHTWQTV DFVRKKHAQF 

        70         80         90        100        110        120 
GGFSYKRMTV LEAVDMLDGL VDESDPDVDF PNSFHAFQTA EGIRKAHPDK DWFHLVGLLH 

       130        140        150        160        170        180 
DLGKVLVLAG EPQWAVVGDT FPVGCRPQAS VVFCDSTFQD NPDLQDPVYS TELGMYQPHC 

       190        200        210        220        230        240 
GLENALMSWG HDEYMYQMMK FNKFSLPGEA FYIIRFHSFY PWHTGGDYRQ LCNEQDLAML 

       250        260        270        280 
PWVQEFNKFD LYTKGSDMPD VDELRPYYQG LIDKYCPGVL CW
Q8WN98 in FASTA format

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