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UniProtKB/Swiss-Prot entry Q8VZA1


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name LAC11_ARATH
Primary accession number Q8VZA1
Secondary accession numbers Q0WM80 Q9LYV9
Integrated into Swiss-Prot on April 3, 2007
Sequence was last modified on March 1, 2002 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 41)
Name and origin of the protein
Protein name Laccase-11 [Precursor]
Synonyms EC 1.10.3.2
Benzenediol:oxygen oxidoreductase 11
Urishiol oxidase 11
Diphenol oxidase 11
Gene name
Name: LAC11
OrderedLocusNames: At5g03260
ORFNames: F15A17_290, MOK16.17
From
Arabidopsis thaliana (Mouse-ear cress) [TaxID: 3702] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
DOI=10.1093/dnares/4.3.215; PubMed=9330910 [NCBI, ExPASy, EBI, Israel, Japan]
Sato S., Kotani H., Nakamura Y., Kaneko T., Asamizu E., Fukami M., Miyajima N., Tabata S.;
"Structural analysis of Arabidopsis thaliana chromosome 5. I. Sequence features of the 1.6 Mb regions covered by twenty physically assigned P1 clones.";
DNA Res. 4:215-230(1997).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
DOI=10.1038/35048507; PubMed=11130714 [NCBI, ExPASy, EBI, Israel, Japan]
Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E., Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K., Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L., O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D., Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M., Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L., Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B., Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P., Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M., Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D., Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A., Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I., Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T., Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A., McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U., Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G., Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W., Bevan M., Fransz P.F.;
"Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
Nature 408:823-826(2000).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=cv. Columbia;
DOI=10.1126/science.1088305; PubMed=14593172 [NCBI, ExPASy, EBI, Israel, Japan]
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.;
"Empirical analysis of transcriptional activity in the Arabidopsis genome.";
Science 302:842-846(2003).
[4]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 219-557.
STRAIN=cv. Columbia;
Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K., Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.;
"Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
[5]
TISSUE SPECIFICITY.
DOI=10.1007/s00425-004-1472-6; PubMed=15940465 [NCBI, ExPASy, EBI, Israel, Japan]
McCaig B.C., Meagher R.B., Dean J.F.D.;
"Gene structure and molecular analysis of the laccase-like multicopper oxidase (LMCO) gene family in Arabidopsis thaliana.";
Planta 221:619-636(2005).
[6]
TISSUE SPECIFICITY.
DOI=10.1093/jxb/erl022; PubMed=16804053 [NCBI, ExPASy, EBI, Israel, Japan]
Cai X., Davis E.J., Ballif J., Liang M., Bushman E., Haroldsen V., Torabinejad J., Wu Y.;
"Mutant identification and characterization of the laccase gene family in Arabidopsis.";
J. Exp. Bot. 57:2563-2569(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AB005240; BAB08386.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AL163002; CAB86093.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY065128; AAL38304.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY081592; AAM10154.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AK229950; BAF01776.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T48347; T48347.
RefSeq NP_195946.2; -.
UniGene At.23614
3D structure databases
HSSP P37064; 1AOZ. [HSSP ENTRY / PDB]
ModBase Q8VZA1.
Organism-specific databases
TAIR At5g03260; -.
Family and domain databases
InterPro IPR001117; Cu-oxidase.
IPR011706; Cu-oxidase_2.
IPR011707; Cu-oxidase_3.
IPR002355; Cu_oxidase_Cu_BS.
IPR008972; Cupredoxin.
IPR017761; Laccase.
Graphical view of domain structure.
Gene3D G3DSA:2.60.40.420; Cupredoxin; 3.
Pfam PF00394; Cu-oxidase; 1.
PF07731; Cu-oxidase_2; 1.
PF07732; Cu-oxidase_3; 1.
Pfam graphical view of domain structure.
PROSITE PS00079; MULTICOPPER_OXIDASE1; 1.
PS00080; MULTICOPPER_OXIDASE2; 1.
BLOCKS Q8VZA1.
Genome annotation databases
GeneID 831887; -.
GenomeReviews BA000015_GR; AT5G03260.
KEGG ath:AT5G03260; -.
NMPDR fig|3702.1.peg.22407; -.
Other
ProtoNet Q8VZA1.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Apoplast; Complete proteome; Copper; Glycoprotein; Lignin degradation; Metal-binding; Oxidoreductase; Repeat; Secreted; Signal.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
SIGNAL   1    23  23     Potential. 
CHAIN   24   557  534     Laccase-11. PRO_0000283639
DOMAIN   31   147  117     Plastocyanin-like 1. 
DOMAIN   158   308  151     Plastocyanin-like 2. 
DOMAIN   406   541  136     Plastocyanin-like 3. 
METAL   81    81        Copper 1; type 2 (By similarity). 
METAL   83    83        Copper 2; type 3 (By similarity). 
METAL   126   126        Copper 2; type 3 (By similarity). 
METAL   128   128        Copper 3; type 3 (By similarity). 
METAL   458   458        Copper 4; type 1 (By similarity). 
METAL   461   461        Copper 1; type 2 (By similarity). 
METAL   463   463        Copper 3; type 3 (By similarity). 
METAL   520   520        Copper 3; type 3 (By similarity). 
METAL   521   521        Copper 4; type 1 (By similarity). 
METAL   522   522        Copper 2; type 3 (By similarity). 
METAL   526   526        Copper 4; type 1 (By similarity). 
CARBOHYD   36    36        N-linked (GlcNAc...) (Potential). 
CARBOHYD   69    69        N-linked (GlcNAc...) (Potential). 
CARBOHYD   77    77        N-linked (GlcNAc...) (Potential). 
CARBOHYD   115   115        N-linked (GlcNAc...) (Potential). 
CARBOHYD   240   240        N-linked (GlcNAc...) (Potential). 
CARBOHYD   296   296        N-linked (GlcNAc...) (Potential). 
CARBOHYD   323   323        N-linked (GlcNAc...) (Potential). 
CARBOHYD   371   371        N-linked (GlcNAc...) (Potential). 
CARBOHYD   381   381        N-linked (GlcNAc...) (Potential). 
CARBOHYD   398   398        N-linked (GlcNAc...) (Potential). 
CARBOHYD   416   416        N-linked (GlcNAc...) (Potential). 
CARBOHYD   440   440        N-linked (GlcNAc...) (Potential). 
Sequence information
Length: 557 AA [This is the length of the unprocessed precursor] Molecular weight: 61748 Da [This is the MW of the unprocessed precursor] CRC64: F84A86C1E44B1E91 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MKMGFLFLFC YLLAFLGYSP VDAAVKKYQF DVQVKNISRI CNAKPIVTVN GMFPGPTVYA 

        70         80         90        100        110        120 
REGDRVIINV TNHVQYNMSI HWHGLKQYRN GWADGPAYIT QCPIQTGQSY LYDFNVTGQR 

       130        140        150        160        170        180 
GTLWWHAHIL WLRATVYGAI VILPAPGKPY PFPQPYQESN IILGEWWNKD VETAVNQANQ 

       190        200        210        220        230        240 
LGAPPPMSDA HTINGKPGPL FPCSEKHTFV IEAEAGKTYL LRIINAALND ELFFGIAGHN 

       250        260        270        280        290        300 
MTVVEIDAVY TKPFTTKAIL LGPGQTTNVL VKTDRSPNRY FMAASPFMDA PVSVDNKTVT 

       310        320        330        340        350        360 
AILQYKGVPN TVLPILPKLP LPNDTSFALD YNGKLKSLNT PNFPALVPLK VDRRLFYTIG 

       370        380        390        400        410        420 
LGINACPTCV NGTNLAASIN NITFIMPKTA LLKAHYSNIS GVFRTDFPDR PPKAFNYTGV 

       430        440        450        460        470        480 
PLTANLGTST GTRLSRVKFN TTIELVLQDT NLLTVESHPF HLHGYNFFVV GTGVGNFDPK 

       490        500        510        520        530        540 
KDPAKFNLVD PPERNTVGVP TGGWAAIRFR ADNPGVWFMH CHLEVHTMWG LKMAFVVENG 

       550 
ETPELSVLPP PKDYPSC 

Q8VZA1 in FASTA format

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