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UniProtKB/Swiss-Prot entry Q8TRZ4

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ACDA1_METAC
Primary accession number Q8TRZ4
Secondary accession numbers None
Integrated into Swiss-Prot on November 21, 2003
Sequence was last modified on June 1, 2002 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 42)
Name and origin of the protein
Protein name Acetyl-CoA decarbonylase/synthase complex subunit alpha 1
Synonyms ACDS complex subunit alpha 1
EC 1.2.99.2
ACDS complex carbon monoxide dehydrogenase 1
ACDS CODH 1
Gene name
Name: cdhA1
OrderedLocusNames: MA_1016
From
Methanosarcina acetivorans [TaxID: 2214] [HAMAP proteome]
Taxonomy Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 35395 / DSM 2834 / JCM 12185 / C2A;
DOI=10.1101/gr.223902; PubMed=11932238 [NCBI, ExPASy, EBI, Israel, Japan]
Galagan J.E., Nusbaum C., Roy A., Endrizzi M.G., Macdonald P., FitzHugh W., Calvo S., Engels R., Smirnov S., Atnoor D., Brown A., Allen N., Naylor J., Stange-Thomann N., DeArellano K., Johnson R., Linton L., McEwan P., McKernan K., Talamas J., Tirrell A., Ye W., Zimmer A., Barber R.D., Cann I., Graham D.E., Grahame D.A., Guss A.M., Hedderich R., Ingram-Smith C., Kuettner H.C., Krzycki J.A., Leigh J.A., Li W., Liu J., Mukhopadhyay B., Reeve J.N., Smith K., Springer T.A., Umayam L.A., White O., White R.H., de Macario E.C., Ferry J.G., Jarrell K.F., Jing H., Macario A.J.L., Paulsen I.T., Pritchett M., Sowers K.R., Swanson R.V., Zinder S.H., Lander E., Metcalf W.W., Birren B.;
"The genome of Methanosarcina acetivorans reveals extensive metabolic and physiological diversity.";
Genome Res. 12:532-542(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE010299; AAM04446.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_615966.1; -.
3D structure databases
ModBase Q8TRZ4.
Enzyme and pathway databases
BioCyc MACE188937:MA1016-MON; -.
Ontologies
GO
GO:0018492; Molecular function: carbon-monoxide dehydrogenase (acceptor) activity (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01137; -; 1.
PBIL [Tree]
InterPro IPR001450; 4Fe4S_Fe_S_bd.
IPR004460; CO_DHase/Ac-CoA_synth_asu.
IPR016101; CO_DHase_a-bundle.
IPR004137; Prismane.
IPR016099; Prismane-like_a/b-sand.
Graphical view of domain structure.
Gene3D G3DSA:1.20.1270.30; CO_DH_a-bundle; 1.
G3DSA:3.40.50.2030; Prismane-like_a/b-sand; 2.
Pfam PF00037; Fer4; 1.
PF03063; Prismane; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00314; cdhA; 1.
PROSITE PS00198; 4FE4S_FER_1; 1.
PS51379; 4FE4S_FER_2; 2.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q8TRZ4.
Genome annotation databases
GeneID 1472906; -.
GenomeReviews AE010299_GR; MA_1016.
KEGG mac:MA1016; -.
NMPDR fig|188937.1.peg.992; -.
Phylogenomic databases
HOGENOM Q8TRZ4; -.
Genome annotation databases
CMR Q8TRZ4; MA_1016.
Other
ProtoNet Q8TRZ4.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
4Fe-4S; Complete proteome; Iron; Iron-sulfur; Metal-binding; Methanogenesis; Nickel; Oxidoreductase; Repeat.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   806  806     Acetyl-CoA decarbonylase/synthase complex subunit alpha 1. PRO_0000155074
DOMAIN   407   436  30     4Fe-4S ferredoxin-type 1. 
DOMAIN   446   475  30     4Fe-4S ferredoxin-type 2. 
METAL   73    73        Iron-sulfur 1 (4Fe-4S) (shared with dimeric partner) (By similarity). 
METAL   76    76        Iron-sulfur 1 (4Fe-4S) (shared with dimeric partner) (By similarity). 
METAL   77    77        Iron-sulfur 2 (4Fe-4S) (By similarity). 
METAL   79    79        Iron-sulfur 2 (4Fe-4S) (By similarity). 
METAL   84    84        Iron-sulfur 2 (4Fe-4S) (By similarity). 
METAL   94    94        Iron-sulfur 2 (4Fe-4S) (By similarity). 
METAL   250   250        Nickel-iron-sulfur (By similarity). 
METAL   278   278        Nickel-iron-sulfur (By similarity). 
METAL   323   323        Nickel-iron-sulfur (By similarity). 
METAL   417   417        Iron-sulfur 3 (4Fe-4S) (Potential). 
METAL   420   420        Iron-sulfur 3 (4Fe-4S) (Potential). 
METAL   423   423        Iron-sulfur 3 (4Fe-4S) (Potential). 
METAL   427   427        Iron-sulfur 3 (4Fe-4S) (Potential). 
METAL   455   455        Iron-sulfur 4 (4Fe-4S) (Potential). 
METAL   458   458        Iron-sulfur 4 (4Fe-4S) (Potential). 
METAL   461   461        Iron-sulfur 4 (4Fe-4S) (Potential). 
METAL   465   465        Iron-sulfur 4 (4Fe-4S) (Potential). 
METAL   523   523        Nickel-iron-sulfur (By similarity). 
METAL   552   552        Nickel-iron-sulfur (By similarity). 
METAL   587   587        Nickel-iron-sulfur (By similarity). 
Sequence information
Length: 806 AA [This is the length of the unprocessed precursor] Molecular weight: 88694 Da [This is the MW of the unprocessed precursor] CRC64: 4D7D376E7718B0B9 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSKLTTGSFS IEDLESVQIT INNIVGAAKE AAEEKAKELE KAGPTLFPGL ESYRDDWNFK 

        70         80         90        100        110        120 
LLDRYEPVIT PMCDQCCYCT YGPCDLSGNK RGACGIDMLG HNGREFFLRV ITGTACHAAH 

       130        140        150        160        170        180 
GRHLLDHLIE TFGEDLPLNL GQSNVLTPNI TISTGLSPKN LGEIKPAMEF VEEQLTQLLA 

       190        200        210        220        230        240 
TVHAGQESAE IDYDSKALFS GSLDHVGMEI SDVVQVAAYD FPKADPEAPL IEIGMGTIDK 

       250        260        270        280        290        300 
SKPFLCVIGH NVGGVTYMMD YMEEHDLTDK MEIAGLCCTA IDLSRYKEAD RRPPYAKVIG 

       310        320        330        340        350        360 
SMSKELKVIR SGMPDVIVVD EQCVRGDIVP EAQKLKIPVI ASNAKIMYGL PNRTDANVDD 

       370        380        390        400        410        420 
VVEELKSGAI PGCVMLDYDK LGELCIRLTM EMGPIRDAEG ITAIPTDEEF ADWVAKCADC 

       430        440        450        460        470        480 
GACMIACPEE LDIPEAMGFA KEGDFSYLEE LHDQCIGCRR CEQVCKKEIP ILNIIEKVAQ 

       490        500        510        520        530        540 
KQIAEEKGWM RAGRGQVSDA EIRAEGLNLV MGTTPGIIAI IGCPNYAEGT KDVYYIAEEF 

       550        560        570        580        590        600 
LKRNFIVVTT GCGAMDIGMF KDEDGKTLYE RFPGGFECGG LVNIGSCVSN AHITGAAEKV 

       610        620        630        640        650        660 
AAIFAQRTLE GNLAEISDYI LNRVGACGLA WGAFSQKASS IGTGCNILGI PAVLGPHSSK 

       670        680        690        700        710        720 
YRRALIAKTY EEDKWKVYDA RNGQEMPIPP APEFLLTTAE TWQEAIPMMA KACIRPSDNS 

       730        740        750        760        770        780 
MGRSIKLTHW MELHKKYLGK DPEDWWKFVR NEADLPLAKR EALLKELESK HGWEIDWKKK 

       790        800 
KIISGPKIKF DVSAQPTNLK RLCKEA
Q8TRZ4 in FASTA format

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