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UniProtKB/Swiss-Prot entry Q8FH03

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ASTE_ECOL6
Primary accession number Q8FH03
Secondary accession numbers None
Integrated into Swiss-Prot on April 26, 2004
Sequence was last modified on March 1, 2003 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 36)
Name and origin of the protein
Protein name Succinylglutamate desuccinylase
Synonym EC 3.5.1.96
Gene name
Name: astE
OrderedLocusNames: c2144
From
Escherichia coli O6 [TaxID: 217992] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=O6:H1 / CFT073 / ATCC 700928 / UPEC;
DOI=10.1073/pnas.252529799; PubMed=12471157 [NCBI, ExPASy, EBI, Israel, Japan]
Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D., Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F., Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T., Donnenberg M.S., Blattner F.R.;
"Extensive mosaic structure revealed by the complete genome sequence of uropathogenic Escherichia coli.";
Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE014075; AAN80603.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_754038.1; -.
3D structure databases
SMR Q8FH03; 1-322.
ModBase Q8FH03.
Ontologies
GO
GO:0016788; Molecular function: hydrolase activity, acting on ester bonds (inferred from electronic annotation from HAMAP).
GO:0009017; Molecular function: succinylglutamate desuccinylase activity (inferred from electronic annotation from EC).
GO:0008270; Molecular function: zinc ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0019544; Biological process: arginine catabolic process to glutamate (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00767; -; 1.
PBIL [Tree]
InterPro IPR007036; Aste_AspA.
IPR016681; SuccinylGlu_desuccinylase.
Graphical view of domain structure.
Pfam PF04952; AstE_AspA; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF017020; AstE; 1.
TIGRFAMs TIGR03242; arg_catab_astE; 1.
ProtoNet Q8FH03.
Genome annotation databases
GeneID 1036569; -.
GenomeReviews AE014075_GR; c2144.
KEGG ecc:c2144; -.
Phylogenomic databases
HOGENOM Q8FH03; -.
Genome annotation databases
CMR Q8FH03; c2144.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Arginine metabolism; Complete proteome; Hydrolase; Metal-binding; Zinc.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   322  322     Succinylglutamate desuccinylase. PRO_0000174641
ACT_SITE   210   210        Potential. 
METAL   53    53        Zinc (By similarity). 
METAL   56    56        Zinc (By similarity). 
METAL   147   147        Zinc (By similarity). 
Sequence information
Length: 322 AA [This is the length of the unprocessed precursor] Molecular weight: 35855 Da [This is the MW of the unprocessed precursor] CRC64: 500A2B5E5E302454 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MDNFLALTLT GKKPVITERE INGVRWRWLG DGVLELTPLT PPQGVLVISA GIHGNETAPV 

        70         80         90        100        110        120 
EMLDALLGAI SHGEIPLRWR LLVILGNPPA LKQGKRYCHS DMNRMFGGRW QLFAESGETC 

       130        140        150        160        170        180 
RARELEQCLE DFYDQGKESV RWHLDLHTAI RGSLHPQFGV LPQRDIPWDE KFLTWLGAAG 

       190        200        210        220        230        240 
LEALVFHQEP GGTFTHFSAR HFGALACTLE LGKALPFGQN DLRQFAVTAS AIAALLSGES 

       250        260        270        280        290        300 
VGIVRTPPLR YRVVSQITRH SPSFEMHMAN DTLNFMPFEK GTLLAQDGEE RFTVTHDVEY 

       310        320 
VLFPNPLVAL GLRAGLMLEK IS
Q8FH03 in FASTA format

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