ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry Q8EAP2

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name MAO1_SHEON
Primary accession number Q8EAP2
Secondary accession numbers None
Integrated into Swiss-Prot on December 6, 2005
Sequence was last modified on March 1, 2003 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 38)
Name and origin of the protein
Protein name NAD-dependent malic enzyme
Synonyms NAD-ME
EC 1.1.1.38
Gene name
Name: sfcA
OrderedLocusNames: SO_3855
From
Shewanella oneidensis [TaxID: 70863] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales; Shewanellaceae; Shewanella.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=MR-1;
DOI=10.1038/nbt749; PubMed=12368813 [NCBI, ExPASy, EBI, Israel, Japan]
Heidelberg J.F., Paulsen I.T., Nelson K.E., Gaidos E.J., Nelson W.C., Read T.D., Eisen J.A., Seshadri R., Ward N.L., Methe B.A., Clayton R.A., Meyer T., Tsapin A., Scott J., Beanan M.J., Brinkac L.M., Daugherty S.C., DeBoy R.T., Dodson R.J., Durkin A.S., Haft D.H., Kolonay J.F., Madupu R., Peterson J.D., Umayam L.A., White O., Wolf A.M., Vamathevan J.J., Weidman J.F., Impraim M., Lee K., Berry K.J., Lee C., Mueller J., Khouri H.M., Gill J., Utterback T.R., McDonald L.A., Feldblyum T.V., Smith H.O., Venter J.C., Nealson K.H., Fraser C.M.;
"Genome sequence of the dissimilatory metal ion-reducing bacterium Shewanella oneidensis.";
Nat. Biotechnol. 20:1118-1123(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE014299; AAN56831.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_719387.1; -.
3D structure databases
HSSP P27443; 1O0S. [HSSP ENTRY / PDB]
ModBase Q8EAP2.
Enzyme and pathway databases
BioCyc SONE211586:SO_3855-MON; -.
Ontologies
GO
GO:0016619; Molecular function: malate dehydrogenase (oxaloacetate-decarboxylating) activity (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01619; -; 1.
PBIL [Tree]
InterPro IPR015884; Malic_enzyme_CS.
IPR012301; Malic_N.
IPR012302; Malic_NAD_bd.
IPR001891; Malic_OxRdtase.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF00390; malic; 1.
PF03949; Malic_M; 1.
Pfam graphical view of domain structure.
PRINTS PR00072; MALOXRDTASE.
PROSITE PS00331; MALIC_ENZYMES; 1.
BLOCKS Q8EAP2.
Genome annotation databases
GeneID 1171498; -.
GenomeReviews AE014299_GR; SO_3855.
KEGG son:SO_3855; -.
NMPDR fig|211586.1.peg.3501; -.
TIGR SO_3855; -.
Phylogenomic databases
HOGENOM Q8EAP2; -.
Other
ProtoNet Q8EAP2.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Metal-binding; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   562  562     NAD-dependent malic enzyme. PRO_0000160232
ACT_SITE   101   101        Proton donor (By similarity). 
ACT_SITE   172   172        Proton acceptor (By similarity). 
METAL   243   243        Divalent metal cation (By similarity). 
METAL   244   244        Divalent metal cation (By similarity). 
METAL   267   267        Divalent metal cation (By similarity). 
BINDING   154   154        NAD (By similarity). 
BINDING   267   267        NAD (By similarity). 
BINDING   415   415        NAD (By similarity). 
SITE   267   267  1     Important for activity (By similarity). 
Sequence information
Length: 562 AA [This is the length of the unprocessed precursor] Molecular weight: 62162 Da [This is the MW of the unprocessed precursor] CRC64: E6DA84E0EDFF8E0E [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MDDNKRPLYL PFAGPAILEA PLINKGSAFS EEERIFFNLE GLVPYAIETI EEQASRAYDQ 

        70         80         90        100        110        120 
FRSFNNDLDK HIYLRNIQDT NETLFYRLVQ NHISEMMPII YTPTVGLACE RFSKNYRRNR 

       130        140        150        160        170        180 
GLFISYPNKD RIDDILNNST RQKVKIIVVT DGERILGLGD QGIGGMGIPI GKLSLYTSCG 

       190        200        210        220        230        240 
GISPAYTLPI TLDVGTDNPQ LLEDPMYMGW RHPRIGGEEY AEFIEAFMQA VHVRWPDTLI 

       250        260        270        280        290        300 
QFEDFAQKNA MPILERYKER YCCFNDDIQG TAAVTVGSLL AACKAAGTEL NKQRVAFLGA 

       310        320        330        340        350        360 
GSAGCGIAEA IVAQMVSEGI SDEQARSQVC MVDRWGLLLD NMPNLLPFQQ KLAQKCADIS 

       370        380        390        400        410        420 
HWNNFSDNIS LLDVVNNAKP TVLIGVSGAP GLFTEEIVRA MHSHCPRPII FPLSNPTSRV 

       430        440        450        460        470        480 
EATPKDILHW TSGQALVATG SPFEPVVVDG ETYEIAQCNN SFIFPGIGLG VLASGARHVS 

       490        500        510        520        530        540 
DAMLMASSRA LAECSPLAIN GSGPLLPKLE DIHSVSKHIA FAVGKVAIEQ GLSLPASDEL 

       550        560 
LMQSIEDNFW KPEYRRYKRT SF
Q8EAP2 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA) 		Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Hosted by kr flag YPRC Korea Mirror sites: Australia Brazil Canada China Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!