NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482;
DOI=10.1126/science.1080029; PubMed=12663928 [NCBI, ExPASy, EBI, Israel, Japan]
Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C., Hooper L.V., Gordon J.I.;
"A genomic view of the human-Bacteroides thetaiotaomicron symbiosis.";
Science 299:2074-2076(2003).

Comments

CATALYTIC ACTIVITY: ATP + acetate = ADP + acetyl phosphate.
CATALYTIC ACTIVITY: ATP + propanoate = ADP + propanoyl phosphate.
PATHWAY: Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2 .
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
SIMILARITY: Belongs to the acetokinase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AE015928; AAO78798.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

NP_812604.1; -.

3D structure databases

HSSP

P38502; 1G99. [HSSP ENTRY / PDB]

ModBase

Q8A1G8.

Enzyme and pathway databases

BioCyc

BTHE226186:BT_3693-MON; -.

Ontologies

GO:0005737;	Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0008776;	Molecular function: acetate kinase activity (inferred from electronic annotation from HAMAP).
GO:0016310;	Biological process: phosphorylation (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_00020; -; 1.
PBIL [Tree]

InterPro

IPR000890; Acetate_kin.
IPR004372; AckA.
Graphical view of domain structure.

PANTHER

PTHR21060; Acetate_kin; 1.
PTHR21060:SF11; AckA; 1.

Pfam

PF00871; Acetate_kinase; 1.
Pfam graphical view of domain structure.

PIRSF

PIRSF000722; Acetate_prop_kin; 1.

PRINTS

PR00471; ACETATEKNASE.

TIGRFAMs

TIGR00016; ackA; 1.

PROSITE

PS01075; ACETATE_KINASE_1; 1.
PS01076; ACETATE_KINASE_2; 1.

Genome annotation databases

GeneID

1076294; -.

GenomeReviews

AE015928_GR; BT_3693.

KEGG

bth:BT_3693; -.

NMPDR

fig|226186.1.peg.3691; -.

Phylogenomic databases

HOGENOM

Q8A1G8; -.

Genome annotation databases

CMR

Q8A1G8; BT_3693.

Other

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Cytoplasm; Kinase; Transferase.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 399`	`399`		`Acetate kinase.`	`PRO_0000107535`

Sequence information

Length: 399 AA [This is the length of the unprocessed precursor]

Molecular weight: 43340 Da [This is the MW of the unprocessed precursor]

CRC64: 9161287FEC871298 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MKILVLNCGS SSIKYKLFDM TTKEVIAQGG IEKIGLKGSF LKLTLPNGEK KVLEKDIPEH 

        70         80         90        100        110        120 
TIGVEFILNT LISPEYGAIK SLDEINAVGH RMVHGGERFS ESVLLNKEVL EAFAACNDLA 

       130        140        150        160        170        180 
PLHNPANLKG VNAVSAILPN IPQVGVFDTA FHQTMPDYAY MYAIPYEMYE KYGVRRYGFH 

       190        200        210        220        230        240 
GTSHRYVSKR VCEFLGVNPV GQKIITCHIG NGGSIAAIKD GKCIDTTMGL TPLEGLMMGT 

       250        260        270        280        290        300 
RSGDIDAGAV TFIMEKEGLN TTGISNLLNK KSGVLGISGV SSDMRELLAA CANGNERAIL 

       310        320        330        340        350        360 
AEKMYYYRIK KYIGAYAAAL GGVDIILFTG GVGENQFECR ESVCKDMEFM GIKLDNNVNA 

       370        380        390 
KVRGEEAIIS TADSKVKVVV IPTDEELLIA SDTMDILKK

Q8A1G8 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools