[1]	NUCLEOTIDE SEQUENCE [GENOMIC DNA]. STRAIN=CBS 137; DOI=10.1016/j.femsyr.2004.06.012; PubMed=15381122 [NCBI, ExPASy, EBI, Israel, Japan] Neves L., Oliveira R., Lucas C.; "Yeast orthologues associated with glycerol transport and metabolism."; FEMS Yeast Res. 5:51-62(2004).

Comments

CATALYTIC ACTIVITY: sn-glycerol 3-phosphate + NAD⁺ = glycerone phosphate + NADH.
SIMILARITY: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AY289713; AAP44104.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

3D structure databases

HSSP

P90551; 1EVY. [HSSP ENTRY / PDB]

ModBase

Q7ZA45.

Family and domain databases

InterPro

IPR013328; DHase_multihelical.
IPR016040; NAD(P)-bd.
IPR017751; NAD-dep_Gly3P_DH_euk.
IPR006168; NAD-dep_Gly3P_DHase.
IPR011128; NAD-dep_Gly3P_DHase_N.
IPR006109; NAD_Gly3P_DHase_C.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.50.720; NAD(P)-bd; 1.
G3DSA:1.10.1040.10; Opine_DH; 1.

PANTHER

PTHR11728; NAD_Gly3P_DH; 1.

Pfam

PF07479; NAD_Gly3P_dh_C; 1.
PF01210; NAD_Gly3P_dh_N; 1.
Pfam graphical view of domain structure.

PIRSF

PIRSF000114; Glycerol-3-P_dh; 1.

PRINTS

PR00077; GPDHDRGNASE.

ProDom

PD001278; NAD_Gly3P_C; 1.
[Domain structure / List of seq. sharing at least 1 domain]

PROSITE

PS00957; NAD_G3PDH; 1.

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

NAD; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 411`	`411`	`Glycerol-3-phosphate dehydrogenase [NAD+].`	`PRO_0000138090`
`NP_BIND`	`71 76`	`6`	`NAD (By similarity).`
`REGION`	`340 341`	`2`	`Substrate binding (By similarity).`
`ACT_SITE`	`275 275`		`Proton acceptor (By similarity).`
`BINDING`	`159 159`		`NAD (By similarity).`
`BINDING`	`182 182`		`NAD; via amide nitrogen (By similarity).`
`BINDING`	`182 182`		`Substrate (By similarity).`
`BINDING`	`215 215`		`NAD; via amide nitrogen (By similarity).`
`BINDING`	`340 340`		`NAD (By similarity).`

Sequence information

Length: 411 AA [This is the length of the unprocessed precursor]

Molecular weight: 45332 Da [This is the MW of the unprocessed precursor]

CRC64: A155FF3F16521A86 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MFSISRITRT SSFTTQFRAL YRFKHSARKL QSIPFSIYKK MSAADRLNQT HDILSESVQA 

        70         80         90        100        110        120 
VENPFKVTVI GSGNWGTTIS KVVAENAALR PHLFVKRVDM WVFEETVDGQ KLTEIINTKH 

       130        140        150        160        170        180 
QNVKYLPNID LPENLVANPD LVSAVKDADI LVFNIPHQFL PRIVSQLQGN IKKDARAISC 

       190        200        210        220        230        240 
LKGFDVSKDG VKLLSTYVTE KLGITCGALS GANLAPEVAK ENWSETTVAY ELPKDFKGEG 

       250        260        270        280        290        300 
KDVDHAVLKA LFHRPYFHVN VIDDVAGISV AGALKNVVAL GCGFVEGLGW GNNASAAIQR 

       310        320        330        340        350        360 
VGLGEIIKFG QMFFPDSRVE TYYQESAGVA DLITTCSGGR NVRVATHMAK TGKSAEECEK 

       370        380        390        400        410 
ELLNGQSAQV FTHVRRSTSG WPSAVRPMNS FCSRPFTRLS TRTLLWTLCQ T

Q7ZA45 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools