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UniProtKB/Swiss-Prot entry Q7WH69


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name QUEF_BORBR
Primary accession number Q7WH69
Secondary accession numbers None
Integrated into Swiss-Prot on November 22, 2005
Sequence was last modified on November 22, 2005 (Sequence version 2)
Annotations were last modified on    September 2, 2008 (Entry version 35)
Name and origin of the protein
Protein name NADPH-dependent 7-cyano-7-deazaguanine reductase
Synonyms EC 1.7.1.13
7-cyano-7-carbaguanine reductase
PreQ(0) reductase
NADPH-dependent nitrile oxidoreductase
Gene name
Name: queF
OrderedLocusNames: BB3340
From
Bordetella bronchiseptica (Alcaligenes bronchisepticus) [TaxID: 518] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; Alcaligenaceae; Bordetella.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=RB50 / ATCC BAA-588 / NCTC 13252;
DOI=10.1038/ng1227; PubMed=12910271 [NCBI, ExPASy, EBI, Israel, Japan]
Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.R., Harris D.E., Holden M.T.G., Churcher C.M., Bentley S.D., Mungall K.L., Cerdeno-Tarraga A.-M., Temple L., James K.D., Harris B., Quail M.A., Achtman M., Atkin R., Baker S., Basham D., Bason N., Cherevach I., Chillingworth T., Collins M., Cronin A., Davis P., Doggett J., Feltwell T., Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K., Leather S., Moule S., Norberczak H., O'Neil S., Ormond D., Price C., Rabbinowitsch E., Rutter S., Sanders M., Saunders D., Seeger K., Sharp S., Simmonds M., Skelton J., Squares R., Squares S., Stevens K., Unwin L., Whitehead S., Barrell B.G., Maskell D.J.;
"Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica.";
Nat. Genet. 35:32-40(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BX640447; CAE33832.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_889875.2; -.
3D structure databases
ModBase Q7WH69.
Enzyme and pathway databases
BioCyc BBRO257310:BB3340-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0046857; Molecular function: oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor (inferred from electronic annotation from HAMAP).
GO:0008616; Biological process: queuosine biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00817; -; 1.
PBIL [Tree]
InterPro IPR016428; CN_OxRdtase_NADPH-dep_YqcD.
IPR001474; GTP_CycOHase_I.
Graphical view of domain structure.
Pfam PF01227; GTP_cyclohydroI; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF004750; Nitrile_oxidored_YqcD_prd; 1.
TIGRFAMs TIGR03138; QueF; 1.
BLOCKS Q7WH69.
Genome annotation databases
GeneID 2660959; -.
GenomeReviews BX470250_GR; BB3340.
KEGG bbr:BB3340; -.
NMPDR fig|257310.1.peg.3322; -.
Phylogenomic databases
HOGENOM Q7WH69; -.
Genome annotation databases
CMR Q7WH69; BB3340.
Other
ProtoNet Q7WH69.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; NADP; Oxidoreductase; Queuosine biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   273  273     NADPH-dependent 7-cyano-7-deazaguanine reductase. PRO_0000163020
Sequence information
Length: 273 AA [This is the length of the unprocessed precursor] Molecular weight: 30651 Da [This is the MW of the unprocessed precursor] CRC64: C742FF9C344C50D2 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSLSNAPLGQ HVAYPSQYDP GLLFPIPRAT NRASLQLGAT LPFTGVDLWN AYELSWLDAR 

        70         80         90        100        110        120 
GKPRVAMATF SFPADSPNIV ESKSFKLYLN SFNQTRLPNA QALRDRLERD LAAAAGAPVG 

       130        140        150        160        170        180 
LEFISPQRFG ELNMAELDGI YIDKLDIEID TYEPAPQLLQ CAPGDEVEET LATRLLKSNC 

       190        200        210        220        230        240 
PVTGQPDWAS LQVRYRGRPI DRAALLKYVV SFRQHAEFHE HCVERIFGDI MRACQPRQLT 

       250        260        270 
VYARYTRRGG LDINPWRSNF ESAPPADVRT ARQ 

Q7WH69 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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NPSA logo NPSA Sequence analysis tools

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