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UniProtKB/Swiss-Prot entry Q7VWZ0


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PROA_BORPE
Primary accession number Q7VWZ0
Secondary accession numbers None
Integrated into Swiss-Prot on December 15, 2003
Sequence was last modified on October 1, 2003 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 37)
Name and origin of the protein
Protein name Gamma-glutamyl phosphate reductase
Synonyms GPR
EC 1.2.1.41
Glutamate-5-semialdehyde dehydrogenase
Glutamyl-gamma-semialdehyde dehydrogenase
GSA dehydrogenase
Gene name
Name: proA
OrderedLocusNames: BP2041
From
Bordetella pertussis [TaxID: 520] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; Alcaligenaceae; Bordetella.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Tohama I / ATCC BAA-589 / NCTC 13251;
DOI=10.1038/ng1227; PubMed=12910271 [NCBI, ExPASy, EBI, Israel, Japan]
Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.R., Harris D.E., Holden M.T.G., Churcher C.M., Bentley S.D., Mungall K.L., Cerdeno-Tarraga A.-M., Temple L., James K.D., Harris B., Quail M.A., Achtman M., Atkin R., Baker S., Basham D., Bason N., Cherevach I., Chillingworth T., Collins M., Cronin A., Davis P., Doggett J., Feltwell T., Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K., Leather S., Moule S., Norberczak H., O'Neil S., Ormond D., Price C., Rabbinowitsch E., Rutter S., Sanders M., Saunders D., Seeger K., Sharp S., Simmonds M., Skelton J., Squares R., Squares S., Stevens K., Unwin L., Whitehead S., Barrell B.G., Maskell D.J.;
"Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica.";
Nat. Genet. 35:32-40(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BX640417; CAE42320.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_880708.1; -.
3D structure databases
ModBase Q7VWZ0.
Enzyme and pathway databases
BioCyc BPER257313:BP2041-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0004350; Molecular function: glutamate-5-semialdehyde dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0006561; Biological process: proline biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00412; -; 1.
PBIL [Tree]
InterPro IPR016163; Ald_DHase_C.
IPR016162; Ald_DHase_N.
IPR015590; Aldehyde_DHase.
IPR000965; Gglut_pp_reduct.
IPR012134; Glu-5-SA_DHase.
Graphical view of domain structure.
Gene3D G3DSA:3.40.309.10; Aldehyde_dehydrogenase_C; 1.
G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1.
PANTHER PTHR11063:SF1; GSA_DH; 1.
Pfam PF00171; Aldedh; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000151; GPR; 1.
TIGRFAMs TIGR00407; proA; 1.
PROSITE PS01223; PROA; 1.
BLOCKS Q7VWZ0.
Genome annotation databases
GeneID 2665771; -.
GenomeReviews BX470248_GR; BP2041.
KEGG bpe:BP2041; -.
NMPDR fig|257313.1.peg.1783; -.
Phylogenomic databases
HOGENOM Q7VWZ0; -.
Genome annotation databases
CMR Q7VWZ0; BP2041.
Other
ProtoNet Q7VWZ0.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Complete proteome; Cytoplasm; NADP; Oxidoreductase; Proline biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   419  419     Gamma-glutamyl phosphate reductase. PRO_0000189703
Sequence information
Length: 419 AA [This is the length of the unprocessed precursor] Molecular weight: 44328 Da [This is the MW of the unprocessed precursor] CRC64: 0A67A28AD1F9715C [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSSIETYMQS VGEQARTASR AMMRATGAAK NQALLAMAEA ILAQRAELQA ANAKDVAAAR 

        70         80         90        100        110        120 
ANGLEAALLD RLTLSDRSIE LMAEGLRQIA ALPDPGGSIT ATSVRPNGMR VAQMRVPLGV 

       130        140        150        160        170        180 
IGIIYESRPN VTIDAAALCL KSGNATILRG GSEALHSNVA LGRIVQAGLQ AAGLPTAAVQ 

       190        200        210        220        230        240 
VIDTTDRAAV GKLVTMTEHV DVIVPRGGKG LISRLAQEAR VPLIKHLDGN CHVYVDAAAD 

       250        260        270        280        290        300 
LAKAHDIAFN AKTYRYGVCG AMETLLVHAD VAQRLLPALG QALREHGVEL RGCARALQWL 

       310        320        330        340        350        360 
PEGKPADDAD WATEYLGPIL AVRVVDTIDE AMDHISRWGS GHTDAIVTEN LSAAQRFQRE 

       370        380        390        400        410 
VDSSSVYVNL PTCFADGFEY GLGAEIGIST NRLHARGPVG LEGLTTLKWV LNGEGQVRA 

Q7VWZ0 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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NPSA logo NPSA Sequence analysis tools

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