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UniProtKB/Swiss-Prot entry Q7NTY1


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name GUAC_CHRVO
Primary accession number Q7NTY1
Secondary accession numbers None
Integrated into Swiss-Prot on July 10, 2007
Sequence was last modified on December 15, 2003 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 33)
Name and origin of the protein
Protein name GMP reductase
Synonyms EC 1.7.1.7
Guanosine 5'-monophosphate oxidoreductase
Guanosine monophosphate reductase
Gene name
Name: guaC
OrderedLocusNames: CV_2922
From
Chromobacterium violaceum [TaxID: 536] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae; Chromobacterium.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 12472 / DSM 30191 / IFO 12614 / JCM 1249 / NCIB 9131;
DOI=10.1073/pnas.1832124100; PubMed=14500782 [NCBI, ExPASy, EBI, Israel, Japan]
Vasconcelos A.T.R., de Almeida D.F., Hungria M., Guimaraes C.T., Antonio R.V., Almeida F.C., de Almeida L.G.P., de Almeida R., Alves-Gomes J.A., Andrade E.M., Araripe J., de Araujo M.F.F., Astolfi-Filho S., Azevedo V., Baptista A.J., Bataus L.A.M., Batista J.S., Belo A., van den Berg C., Bogo M., Bonatto S., Bordignon J., Brigido M.M., Brito C.A., Brocchi M., Burity H.A., Camargo A.A., Cardoso D.D.P., Carneiro N.P., Carraro D.M., Carvalho C.M.B., Cascardo J.C.M., Cavada B.S., Chueire L.M.O., Creczynski-Pasa T.B., Cunha-Junior N.C., Fagundes N., Falcao C.L., Fantinatti F., Farias I.P., Felipe M.S.S., Ferrari L.P., Ferro J.A., Ferro M.I.T., Franco G.R., Freitas N.S.A., Furlan L.R., Gazzinelli R.T., Gomes E.A., Goncalves P.R., Grangeiro T.B., Grattapaglia D., Grisard E.C., Hanna E.S., Jardim S.N., Laurino J., Leoi L.C.T., Lima L.F.A., Loureiro M.F., Lyra M.C.C.P., Madeira H.M.F., Manfio G.P., Maranhao A.Q., Martins W.S., di Mauro S.M.Z., de Medeiros S.R.B., Meissner R.V., Moreira M.A.M., Nascimento F.F., Nicolas M.F., Oliveira J.G., Oliveira S.C., Paixao R.F.C., Parente J.A., Pedrosa F.O., Pena S.D.J., Pereira J.O., Pereira M., Pinto L.S.R.C., Pinto L.S., Porto J.I.R., Potrich D.P., Ramalho-Neto C.E., Reis A.M.M., Rigo L.U., Rondinelli E., Santos E.B.P., Santos F.R., Schneider M.P.C., Seuanez H.N., Silva A.M.R., da Silva A.L.C., Silva D.W., Silva R., Simoes I.C., Simon D., Soares C.M.A., Soares R.B.A., Souza E.M., Souza K.R.L., Souza R.C., Steffens M.B.R., Steindel M., Teixeira S.R., Urmenyi T., Vettore A., Wassem R., Zaha A., Simpson A.J.G.;
"The complete genome sequence of Chromobacterium violaceum reveals remarkable and exploitable bacterial adaptability.";
Proc. Natl. Acad. Sci. U.S.A. 100:11660-11665(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE016825; AAQ60590.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_902592.1; -.
3D structure databases
HSSP P12268; 1B3O. [HSSP ENTRY / PDB]
ModBase Q7NTY1.
Enzyme and pathway databases
BioCyc CVIO243365:CV_2922-MON; -.
Ontologies
GO
GO:0003920; Molecular function: GMP reductase activity (inferred from electronic annotation from HAMAP).
GO:0006163; Biological process: purine nucleotide metabolic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01511; -; 1.
PBIL [Tree]
InterPro IPR013785; Aldolase_TIM.
IPR005994; GMP_reduct2.
IPR015875; IMP_DH/GMP_Rdtase_CS.
IPR001093; IMP_DHase_GMPRtase.
Graphical view of domain structure.
Gene3D G3DSA:3.20.20.70; Aldolase_TIM; 1.
Pfam PF00478; IMPDH; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF036500; GMP_red_Firmic; 1.
ProDom PD149806; TMP_synthase; 1.
[Domain structure / List of seq. sharing at least 1 domain]
PROSITE PS00487; IMP_DH_GMP_RED; FALSE_NEG.
BLOCKS Q7NTY1.
Genome annotation databases
GeneID 2547468; -.
GenomeReviews AE016825_GR; CV_2922.
KEGG cvi:CV_2922; -.
NMPDR fig|243365.1.peg.2922; -.
Phylogenomic databases
HOGENOM Q7NTY1; -.
Genome annotation databases
CMR Q7NTY1; CV_2922.
Other
ProtoNet Q7NTY1.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   316  316     GMP reductase. PRO_0000294271
NP_BIND   202   225  24     NADP (Potential). 
ACT_SITE   175   175        Thioimidate intermediate (By similarity). 
Sequence information
Length: 316 AA [This is the length of the unprocessed precursor] Molecular weight: 34582 Da [This is the MW of the unprocessed precursor] CRC64: B010B6BA09FC9A8A [This is a checksum on the sequence]
        10         20         30         40         50         60 
MIKTELNYGD VYLVPKKTVV DSRKECDTSV QFGPRRFAMP VYPSNMKSVV SAETCELFAR 

        70         80         90        100        110        120 
EGWFYTLHRF NVDAVAFTRY MQEQGLFASI SVGVNDDTYE QLDALKAAGL SPEYMTLDIA 

       130        140        150        160        170        180 
NAWCVKAERM IKHIKQHFPN TFLIGGNVAT AEAARDLEAW GCDAIKAGIA GGRVCITKNK 

       190        200        210        220        230        240 
TGFHRPMVST VRDCVAAVTI PVIADGGIVE HGDIAKALVC GATMVMAGSL FAGYDESAGD 

       250        260        270        280        290        300 
IVEIAGKHYK EYFGSASQFN KGAYVNVEGK KILVEYKGSM GKLLRELQED LQSSVSYAGG 

       310 
TTLAALREVE MIQVYR 

Q7NTY1 in FASTA format

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