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UniProtKB/Swiss-Prot entry Q7NSD8


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name HMP_CHRVO
Primary accession number Q7NSD8
Secondary accession numbers None
Integrated into Swiss-Prot on September 13, 2004
Sequence was last modified on December 15, 2003 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 37)
Name and origin of the protein
Protein name Flavohemoprotein
Synonyms Hemoglobin-like protein
Flavohemoglobin
Nitric oxide dioxygenase
NO oxygenase
NOD
EC 1.14.12.17
Gene name
Name: hmp
Synonyms: hmpA
OrderedLocusNames: CV_3488
From
Chromobacterium violaceum [TaxID: 536] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae; Chromobacterium.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 12472 / DSM 30191 / IFO 12614 / JCM 1249 / NCIB 9131;
DOI=10.1073/pnas.1832124100; PubMed=14500782 [NCBI, ExPASy, EBI, Israel, Japan]
Vasconcelos A.T.R., de Almeida D.F., Hungria M., Guimaraes C.T., Antonio R.V., Almeida F.C., de Almeida L.G.P., de Almeida R., Alves-Gomes J.A., Andrade E.M., Araripe J., de Araujo M.F.F., Astolfi-Filho S., Azevedo V., Baptista A.J., Bataus L.A.M., Batista J.S., Belo A., van den Berg C., Bogo M., Bonatto S., Bordignon J., Brigido M.M., Brito C.A., Brocchi M., Burity H.A., Camargo A.A., Cardoso D.D.P., Carneiro N.P., Carraro D.M., Carvalho C.M.B., Cascardo J.C.M., Cavada B.S., Chueire L.M.O., Creczynski-Pasa T.B., Cunha-Junior N.C., Fagundes N., Falcao C.L., Fantinatti F., Farias I.P., Felipe M.S.S., Ferrari L.P., Ferro J.A., Ferro M.I.T., Franco G.R., Freitas N.S.A., Furlan L.R., Gazzinelli R.T., Gomes E.A., Goncalves P.R., Grangeiro T.B., Grattapaglia D., Grisard E.C., Hanna E.S., Jardim S.N., Laurino J., Leoi L.C.T., Lima L.F.A., Loureiro M.F., Lyra M.C.C.P., Madeira H.M.F., Manfio G.P., Maranhao A.Q., Martins W.S., di Mauro S.M.Z., de Medeiros S.R.B., Meissner R.V., Moreira M.A.M., Nascimento F.F., Nicolas M.F., Oliveira J.G., Oliveira S.C., Paixao R.F.C., Parente J.A., Pedrosa F.O., Pena S.D.J., Pereira J.O., Pereira M., Pinto L.S.R.C., Pinto L.S., Porto J.I.R., Potrich D.P., Ramalho-Neto C.E., Reis A.M.M., Rigo L.U., Rondinelli E., Santos E.B.P., Santos F.R., Schneider M.P.C., Seuanez H.N., Silva A.M.R., da Silva A.L.C., Silva D.W., Silva R., Simoes I.C., Simon D., Soares C.M.A., Soares R.B.A., Souza E.M., Souza K.R.L., Souza R.C., Steffens M.B.R., Steindel M., Teixeira S.R., Urmenyi T., Vettore A., Wassem R., Zaha A., Simpson A.J.G.;
"The complete genome sequence of Chromobacterium violaceum reveals remarkable and exploitable bacterial adaptability.";
Proc. Natl. Acad. Sci. U.S.A. 100:11660-11665(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE016825; AAQ61149.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_903158.1; -.
3D structure databases
ModBase Q7NSD8.
Enzyme and pathway databases
BioCyc CVIO243365:CV_3488-MON; -.
Ontologies
GO
GO:0008941; Molecular function: nitric oxide dioxygenase activity (inferred from electronic annotation from HAMAP).
GO:0005344; Molecular function: oxygen transporter activity (inferred from electronic annotation from HAMAP).
GO:0015671; Biological process: oxygen transport (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01252; -; 1.
PBIL [Tree]
InterPro IPR012292; Globin.
IPR000971; Globin_subset.
IPR001032; Leghaemoglobin.
IPR008333; OxRdtase_FAD-bd.
IPR001433; OxRdtase_FAD/NAD_bd.
Graphical view of domain structure.
Gene3D G3DSA:1.10.490.10; Globin_related; 1.
Pfam PF00970; FAD_binding_6; 1.
PF00042; Globin; 1.
PF00175; NAD_binding_1; 1.
Pfam graphical view of domain structure.
PRINTS PR00188; PLANTGLOBIN.
PROSITE PS51384; FAD_FR; 1.
PS01033; GLOBIN; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q7NSD8.
Genome annotation databases
GeneID 2549191; -.
GenomeReviews AE016825_GR; CV_3488.
KEGG cvi:CV_3488; -.
NMPDR fig|243365.1.peg.3488; -.
Phylogenomic databases
HOGENOM Q7NSD8; -.
Genome annotation databases
CMR Q7NSD8; CV_3488.
Other
ProtoNet Q7NSD8.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Detoxification; FAD; Flavoprotein; Heme; Iron; Metal-binding; NAD; NADP; Oxidoreductase; Oxygen transport; Transport.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   404  404     Flavohemoprotein. PRO_0000052429
DOMAIN   152   263  112     FAD-binding FR-type. 
NP_BIND   206   209  4     FAD (By similarity). 
NP_BIND   276   281  6     NADP (By similarity). 
NP_BIND   396   399  4     FAD (By similarity). 
REGION   1   138  138     Globin. 
REGION   149   404  256     Reductase. 
REGION   267   404  138     NAD or NADP-binding. 
ACT_SITE   95    95        Charge relay system (By similarity). 
ACT_SITE   137   137        Charge relay system (By similarity). 
METAL   85    85        Iron (heme proximal ligand) (By similarity). 
BINDING   190   190        FAD (By similarity). 
SITE   29    29  1     Involved in heme-bound ligand stabilization and O-O bond activation (By similarity). 
SITE   84    84  1     Influences the redox potential of the prosthetic heme and FAD groups (By similarity). 
SITE   395   395  1     Influences the redox potential of the prosthetic heme and FAD groups (By similarity). 
Sequence information
Length: 404 AA [This is the length of the unprocessed precursor] Molecular weight: 44215 Da [This is the MW of the unprocessed precursor] CRC64: F17341E0EEBCD8C4 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MLSEQTRSLV KATVPVLQQH GVALTSHFYR RMFEHNPELK NVFNQGHQHS GQQQQALAMA 

        70         80         90        100        110        120 
VLAYARHIDD PSPLLPVLTR VAHKHVSLGI RAEHYPIVGK HLLASIRELL GEAAGDDLIQ 

       130        140        150        160        170        180 
AWAEAYGLLA DTLIGIENGM YGDATSADGG WSGWRPFRVA KKEIESEEIA SFYLEPSDGG 

       190        200        210        220        230        240 
ALPAFKPGQY VSVKRFVAEW GLSQPRQYSL SDAPNGEYLR ISVKREDAAQ GKPAGRVSNL 

       250        260        270        280        290        300 
LHREVQVGDV LELSAPQGDF FLHEERDGPA VLISAGVGQT PMQAMLGQLL KRGGREVRFL 

       310        320        330        340        350        360 
HAARHGGAHA MGAKVRQLAD RHPQLKVHVC YETPRAQDAI GVDYQAAGRL NLADVKGIAL 

       370        380        390        400 
LPDADYYLCG PLGFMRAQRD SLRGLGVAAD RIHYEVFGSH PGDD 

Q7NSD8 in FASTA format

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View entry in raw text format (no links)
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