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UniProtKB/Swiss-Prot entry Q7ADE7

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ASTB_ECO57
Primary accession number Q7ADE7
Secondary accession number Q8XDY9
Integrated into Swiss-Prot on November 28, 2006
Sequence was last modified on July 5, 2004 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 32)
Name and origin of the protein
Protein name N-succinylarginine dihydrolase
Synonym EC 3.5.3.23
Gene name
Name: astB
OrderedLocusNames: Z2777, ECs2451
From
Escherichia coli O157:H7 [TaxID: 83334] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
DOI=10.1038/35054089; PubMed=11206551 [NCBI, ExPASy, EBI, Israel, Japan]
Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J., Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A., Blattner F.R.;
"Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
Nature 409:529-533(2001).
[2]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
DOI=10.1093/dnares/8.1.11; PubMed=11258796 [NCBI, ExPASy, EBI, Israel, Japan]
Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K., Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S., Shiba T., Hattori M., Shinagawa H.;
"Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and genomic comparison with a laboratory strain K-12.";
DNA Res. 8:11-22(2001).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE005174; AAG56731.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BA000007; BAB35874.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR C90935; C90935.
G85783; G85783.
RefSeq NP_288178.1; -.
NP_310478.1; -.
3D structure databases
SMR Q7ADE7; 2-441.
ModBase Q7ADE7.
Enzyme and pathway databases
BioCyc ECOL83334:ECS2451-MON; -.
Ontologies
GO
GO:0009015; Molecular function: N-succinylarginine dihydrolase activity (inferred from electronic annotation from HAMAP).
GO:0019544; Biological process: arginine catabolic process to glutamate (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01172; -; 1.
PBIL [Tree]
InterPro IPR007079; SuccinylArg_d-OHase_AstB.
Graphical view of domain structure.
Gene3D G3DSA:3.75.10.20; SuccinylArg_di_hydro; 1.
Pfam PF04996; AstB; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR03241; arg_catab_astB; 1.
ProtoNet Q7ADE7.
Genome annotation databases
GeneID 914117; -.
961716; -.
GenomeReviews BA000007_GR; ECs2451.
AE005174_GR; Z2777.
KEGG ece:Z2777; -.
ecs:ECs2451; -.
Phylogenomic databases
HOGENOM Q7ADE7; -.
Genome annotation databases
CMR Q7ADE7; Z2777.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Arginine metabolism; Complete proteome; Hydrolase.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   447  447     N-succinylarginine dihydrolase. PRO_0000262350
REGION   19    28  10     Substrate binding (By similarity). 
REGION   137   138  2     Substrate binding (By similarity). 
ACT_SITE   174   174        By similarity. 
ACT_SITE   248   248        By similarity. 
ACT_SITE   365   365        Nucleophile (By similarity). 
BINDING   110   110        Substrate (By similarity). 
BINDING   212   212        Substrate (By similarity). 
BINDING   250   250        Substrate (By similarity). 
BINDING   359   359        Substrate (By similarity). 
Sequence information
Length: 447 AA [This is the length of the unprocessed precursor] Molecular weight: 49325 Da [This is the MW of the unprocessed precursor] CRC64: 6058E704A1A26CC2 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MNAWEVNFDG LVGLTHHYAG LSFGNKASTR HRFQVSNPRL AAKQGLLKMK TLADAGFPQA 

        70         80         90        100        110        120 
VIPPHERPFI PVLRQLGFSG SDEQVLEKVV RQAPHWLSSV SSASPMWVAN AATIAPSADT 

       130        140        150        160        170        180 
LDGKVHLTVA NLNNKFHRSL EAPVTESLLK AIFNDEEKFS VHSALPQVAL LGDEGAANHN 

       190        200        210        220        230        240 
RLGGHYGEPG MQLFVYGREE GNDTRPSRYP ARQTREASEA VARLNQVNPQ QVIFAQQNPD 

       250        260        270        280        290        300 
VIDQGVFHND VIAVSNRQVL FCHQQAFARQ SQLLANLRAR VNGFMAIEVP ATQVSVSDAV 

       310        320        330        340        350        360 
STYLFNSQLL SRDDGSMMLV LPQECREHAG VWGYLNELLA ADNPISELKV FDLRESMANG 

       370        380        390        400        410        420 
GGPACLRLRV VLTQEERRAV NPAVMMNDTL FNALNDWVDR YYRDRLTAAD LADPQLLREG 

       430        440 
REALDVLSQL LNLGSVYPFQ REGGGNG
Q7ADE7 in FASTA format

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