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UniProtKB/Swiss-Prot entry Q75UG4

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name P4HA3_BOVIN
Primary accession number Q75UG4
Secondary accession numbers None
Integrated into Swiss-Prot on February 5, 2008
Sequence was last modified on July 5, 2004 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 36)
Name and origin of the protein
Protein name Prolyl 4-hydroxylase subunit alpha-3 [Precursor]
Synonyms EC 1.14.11.2
4-PH alpha-3
Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-3
Gene name
Name: P4HA3
From
Bos taurus (Bovine) [TaxID: 9913] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos.
Protein existence 2: Evidence at transcript level;
References
[1]
 NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Adipose tissue;
Tahara K., Aso H., Yamasaki T., Takano S.;
"Cloning and expression of collagen prolyl 4-hydroxylase during bovine adipogenesis.";
Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AB126035; BAD18888.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_001001598.1; -.
UniGene Bt.88095
3D structure databases
ModBase Q75UG4.
Ontologies
GO
GO:0005788; Cellular component: endoplasmic reticulum lumen (inferred from electronic annotation from UniProtKB-SubCell).
GO:0004656; Molecular function: procollagen-proline 4-dioxygenase activity (inferred from electronic annotation from EC).
QuickGo view.
Family and domain databases
InterPro IPR005123; 2OG-FeII_Oase.
IPR006620; Pro_4_hyd_alph.
IPR013547; Pro_4_hyd_alph_N.
IPR011990; TPR-like_helical.
Graphical view of domain structure.
Gene3D G3DSA:1.25.40.10; TPR-like_helical; 1.
Pfam PF03171; 2OG-FeII_Oxy; 1.
PF08336; P4Ha_N; 1.
Pfam graphical view of domain structure.
SMART SM00702; P4Hc; 1.
SMART graphical view of domain structure.
PROSITE PS50005; TPR; FALSE_NEG.
PS50293; TPR_REGION; FALSE_NEG.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q75UG4.
Genome annotation databases
Ensembl ENSBTAG00000006579; Bos taurus. [Contig view]
GeneID 414348; -.
KEGG bta:414348; -.
Phylogenomic databases
HOVERGEN Q75UG4; -.
Other
ProtoNet Q75UG4.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Coiled coil; Dioxygenase; Endoplasmic reticulum; Glycoprotein; Iron; Metal-binding; Oxidoreductase; Signal; TPR repeat; Vitamin C.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
SIGNAL   1    19  19     Potential. 
CHAIN   20   544  525     Prolyl 4-hydroxylase subunit alpha-3. PRO_0000317765
REPEAT   227   260  34     TPR. 
DOMAIN   422   529  108     PKHD. 
COILED   107   131  25     Potential. 
ACT_SITE   520   520        Potential. 
METAL   440   440        Iron (By similarity). 
METAL   442   442        Iron (By similarity). 
METAL   510   510        Iron (By similarity). 
CARBOHYD   248   248        N-linked (GlcNAc...) (Potential). 
CARBOHYD   482   482        N-linked (GlcNAc...) (Potential). 
Sequence information
Length: 544 AA [This is the length of the unprocessed precursor] Molecular weight: 61023 Da [This is the MW of the unprocessed precursor] CRC64: D996D34D44A6F230 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MGPAARLAAL LAVLAFRAGD PAEVAARGDT FSALTSVARA LAPERRLLGL LRRYLRGEEA 

        70         80         90        100        110        120 
RLRDLTRFYH KVLSLHEDSA TPVSNPLLAF TLIKRLQSDW KNVVHSLEAS ENIRALKDGY 

       130        140        150        160        170        180 
ERVEQDLPAF EDLEGAARAL MRLQDVYMLN VKGLARGVFQ RVTGSAVTDL YSPRRLFSLT 

       190        200        210        220        230        240 
GDDCFQVGKV AYDMGDYYHA IPWLEEAVSL FRGSYGEWKT EDEASLEDAL DHLAFAYFQA 

       250        260        270        280        290        300 
GNVLCALNLS REFLLYSPDN KRVARNVLKY EKLLAESPNQ AVAETVMQRP NVPHLQTRDT 

       310        320        330        340        350        360 
YEGLCQTLGS QPTHYRIPSL YCSYETSSSP YLLLQPVRKE VIHLEPYVVL YHDFVSDAEA 

       370        380        390        400        410        420 
QTIRGLAEPW LQRSVVASGE KQLPVEYRIS KSAWLKDTVD PVLVTLDHRI AALTGLDVQP 

       430        440        450        460        470        480 
PYAEYLQVVN YGIGGHYEPH FDHATSPSSP LYRMNSGNRV ATFMIYLSSV EAGGATAFIY 

       490        500        510        520        530        540 
GNFSVPVVKN AALFWWNLHR SGEGDGDTLH AACPVLVGDK WVANKWIHEY GQEFRRPCSS 


RPED
Q75UG4 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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