ID   MQO_MYCPA               Reviewed;         501 AA.
AC   Q73VU0;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   04-NOV-2008, entry version 25.
DE   RecName: Full=Probable malate:quinone oxidoreductase;
DE            EC=1.1.99.16;
DE   AltName: Full=Malate dehydrogenase [acceptor];
DE   AltName: Full=MQO;
GN   Name=mqo; OrderedLocusNames=MAP_2921c;
OS   Mycobacterium paratuberculosis.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Corynebacterineae; Mycobacteriaceae; Mycobacterium;
OC   Mycobacterium avium complex (MAC).
OX   NCBI_TaxID=1770;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-968 / K-10;
RX   PubMed=16116077; DOI=10.1073/pnas.0505662102;
RA   Li L., Bannantine J.P., Zhang Q., Amonsin A., May B.J., Alt D.,
RA   Banerji N., Kanjilal S., Kapur V.;
RT   "The complete genome sequence of Mycobacterium avium subspecies
RT   paratuberculosis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:12344-12349(2005).
CC   -!- CATALYTIC ACTIVITY: (S)-malate + acceptor = oxaloacetate + reduced
CC       acceptor.
CC   -!- COFACTOR: FAD (By similarity).
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle.
CC   -!- SIMILARITY: Belongs to the MQO family.
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DR   EMBL; AE016958; AAS05238.1; -; Genomic_DNA.
DR   RefSeq; NP_961855.1; -.
DR   GeneID; 2721811; -.
DR   GenomeReviews; AE016958_GR; MAP_2921c.
DR   KEGG; mpa:MAP2921c; -.
DR   NMPDR; fig|262316.1.peg.2921; -.
DR   HOGENOM; Q73VU0; -.
DR   GO; GO:0008924; F:malate dehydrogenase (acceptor) activity; IEA:HAMAP.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:HAMAP.
DR   HAMAP; MF_00212; -; 1.
DR   InterPro; IPR006231; Malate_quinone_OxRdtase.
DR   Pfam; PF06039; Mqo; 1.
DR   TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE   3: Inferred from homology;
KW   Complete proteome; FAD; Flavoprotein; Oxidoreductase;
KW   Tricarboxylic acid cycle.
FT   CHAIN         1    501       Probable malate:quinone oxidoreductase.
FT                                /FTId=PRO_0000325500.
SQ   SEQUENCE   501 AA;  54937 MW;  A2BBF534427F4B5E CRC64;
     MSSLARTTRA DVVLVGAGIM SATLGALLRR LQPDWSMTFV ERLDAVAAES SSPWNNAGTG
     HSALCELNYT PQRADGSIDI AKAVRINEQF QVTRQFWAYA VENGMLTDRG FVTPIPHASF
     VRGARAVEYL RRRQQALAPN PLFAGIELIE DADEFARRLP LMADRRDFSE PTALNWARHG
     TDVDFGALSR QLIGFCVRGG ATALFGHQVH NLTRESDGSW TLLIRNRRTG EKHWCNAKFV
     LVGAGGDALP LLQKSGIGEA RGFAGFPIGG RFLRADNPVL TEAHRAKVYG APAPGAPPLG
     ALHLDLRYVN GKPWLVFGPY AGWSPKFLKH GHFTDLPRSV RPHNLVALLG VGVTQLTLLR
     YLIGQLRLSA PDRMRMLREF APTAVDSDWE LTVAGQRVQV IRRDRRRGGV LDFDTTVVAA
     GDGSIAGLLG GSPGASTAVP IMLDVLQRCF ADRYRSWLPA LKEMVPSLGV TLSDEPALYE
     EVYSWGTKIL GLDELDEERP K
//