NUCLEOTIDE SEQUENCE [GENOMIC DNA].
DOI=10.1007/s00239-003-2464-z; PubMed=14562961 [NCBI, ExPASy, EBI, Israel, Japan]
Goulielmos G.N., Loukas M., Bondinas G., Zouros E.;
"Exploring the evolutionary history of the alcohol dehydrogenase gene (Adh) duplication in species of the family tephritidae.";
J. Mol. Evol. 57:170-180(2003).

Comments

CATALYTIC ACTIVITY: An alcohol + NAD⁺ = an aldehyde or ketone + NADH.
SUBUNIT: Homodimer (By similarity).
SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AJ539539; CAD62451.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

3D structure databases

HSSP

P10807; 1B16. [HSSP ENTRY / PDB]

ModBase

Q70UP6.

Family and domain databases

InterPro

IPR002426; Ceratitis_AlcDHase.
IPR002198; DHase_sc/Rdtase_SDR.
IPR002424; Insect_AlcDHase_fam.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.50.720; NAD(P)-bd; 1.

PANTHER

PTHR19410; ADH_short_C2; 1.

Pfam

PF00106; adh_short; 1.
Pfam graphical view of domain structure.

PRINTS

PR01169; CERATITISADH.
PR01167; INSADHFAMILY.
PR00080; SDRFAMILY.

PROSITE

PS00061; ADH_SHORT; 1.

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

NAD; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 258`	`258`	`Alcohol dehydrogenase 2.`	`PRO_0000277840`
`NP_BIND`	`9 33`	`25`	`NAD (By similarity).`
`ACT_SITE`	`150 150`		`Proton acceptor (By similarity).`
`BINDING`	`137 137`		`Substrate (By similarity).`

Sequence information

Length: 258 AA [This is the length of the unprocessed precursor]

Molecular weight: 27968 Da [This is the MW of the unprocessed precursor]

CRC64: 65269A34F96DE474 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MGLSGKNVIF VGGLGFIGYE ACKQLMAKNM ASFFVFDVLD KPEDIKALQA LNPKTKVYYT 

        70         80         90        100        110        120 
KFDITSKQSI KSALADVVSK VKYIDALING AGILTDLNVE LTMNINLIGL INTTLEGLPL 

       130        140        150        160        170        180 
MDKNKQGRGG VIVNIASVLG LEPCPPAAAY CASKFGVMGF SRSIGDPYYY NITGVAVVTF 

       190        200        210        220        230        240 
CPGLTETPLK NNIGSKYTFE YSKKISEELN NTKTQKPEVC GAHLAQVVES HENGGIYISN 

       250 
QGTLAKVTPT VYWQPTYH

Q70UP6 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools