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UniProtKB/Swiss-Prot entry Q6UW32


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name IGFL1_HUMAN
Primary accession number Q6UW32
Secondary accession numbers None
Integrated into Swiss-Prot on December 20, 2005
Sequence was last modified on July 5, 2004 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 29)
Name and origin of the protein
Protein name Insulin growth factor-like family member 1 [Precursor]
Synonyms None
Gene name
Name: IGFL1
ORFNames: UNQ644/PRO1274
From
Homo sapiens (Human) [TaxID: 9606] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [MRNA].
Tang Y.T., Emtage P., Arterburn M., Park E., Boyle B., Hazell S., Polizotto R., Hu T., Funk W.;
"IGFL: a secreted family with conserved cysteine residues and sequence similarity to the IGF superfamily.";
Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
DOI=10.1101/gr.1293003; PubMed=12975309 [NCBI, ExPASy, EBI, Israel, Japan]
Clark H.F., Gurney A.L., Abaya E., Baker K., Baldwin D.T., Brush J., Chen J., Chow B., Chui C., Crowley C., Currell B., Deuel B., Dowd P., Eaton D., Foster J.S., Grimaldi C., Gu Q., Hass P.E., Heldens S., Huang A., Kim H.S., Klimowski L., Jin Y., Johnson S., Lee J., Lewis L., Liao D., Mark M.R., Robbie E., Sanchez C., Schoenfeld J., Seshagiri S., Simmons L., Singh J., Smith V., Stinson J., Vagts A., Vandlen R.L., Watanabe C., Wieand D., Woods K., Xie M.-H., Yansura D.G., Yi S., Yu G., Yuan J., Zhang M., Zhang Z., Goddard A.D., Wood W.I., Godowski P.J., Gray A.M.;
"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.";
Genome Res. 13:2265-2270(2003).
[3]
PROTEIN SEQUENCE OF 25-39.
DOI=10.1110/ps.04682504; PubMed=15340161 [NCBI, ExPASy, EBI, Israel, Japan]
Zhang Z., Henzel W.J.;
"Signal peptide prediction based on analysis of experimentally verified cleavage sites.";
Protein Sci. 13:2819-2824(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AY672111; AAT77785.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY359013; AAQ89372.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_940943.1; -.
UniGene Hs.546554
3D structure databases
ModBase Q6UW32.
Organism-specific databases
H-InvDB HIX0040067; -.
HGNC HGNC:24093; IGFL1.
GenAtlas IGFL1.
HPA HPA014270; -.
MIM 610544; gene. [NCBI / EBI]
GeneCards Q6UW32.
Gene expression databases
ArrayExpress Q6UW32; -.
CleanEx HS_IGFL1; -.
GermOnline ENSG00000188293; Homo sapiens.
Ontologies
GO
GO:0005576; Cellular component: extracellular region (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
ProtoNet Q6UW32.
Genome annotation databases
Ensembl ENSG00000188293; Homo sapiens. [Contig view]
GeneID 374918; -.
KEGG hsa:374918; -.
NMPDR fig|9606.3.peg.16727; -.
Phylogenomic databases
HOGENOM Q6UW32; -.
HOVERGEN Q6UW32; -.
Other
LinkHub Q6UW32; -.
NextBio 100333; -.
SOURCE IGFL1; Homo sapiens.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Direct protein sequencing; Glycoprotein; Secreted; Signal.
Features
SEVIEWER logo Feature table viewer
KeyFrom  To Length Description FTId
SIGNAL   1    24  24      
CHAIN   25   110  86     Insulin growth factor-like family member 1. PRO_0000044633
CARBOHYD   71    71        N-linked (GlcNAc...) (Potential). 
Sequence information
Length: 110 AA [This is the length of the unprocessed precursor] Molecular weight: 12363 Da [This is the MW of the unprocessed precursor] CRC64: 51087608C0D5949E [This is a checksum on the sequence]
        10         20         30         40         50         60 
MAPRGCIVAV FAIFCISRLL CSHGAPVAPM TPYLMLCQPH KRCGDKFYDP LQHCCYDDAV 

        70         80         90        100        110 
VPLARTQTCG NCTFRVCFEQ CCPWTFMVKL INQNCDSART SDDRLCRSVS 

Q6UW32 in FASTA format

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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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