ID   GPD_TRIAT               Reviewed;         427 AA.
AC   Q6UGN0;
DT   10-JAN-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-NOV-2008, entry version 29.
DE   RecName: Full=Glycerol-3-phosphate dehydrogenase [NAD+];
DE            EC=1.1.1.8;
GN   Name=gld1;
OS   Trichoderma atroviride (Hypocrea atroviridis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
OC   Sordariomycetes; Hypocreomycetidae; Hypocreales; Hypocreaceae;
OC   mitosporic Hypocreaceae; Trichoderma.
OX   NCBI_TaxID=63577;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=P1;
RX   PubMed=15531216; DOI=10.1016/j.fgb.2004.09.002;
RA   Seidl V., Seiboth B., Karaffa L., Kubicek C.P.;
RT   "The fungal STRE-element-binding protein Seb1 is involved but not
RT   essential for glycerol dehydrogenase (gld1) gene expression and
RT   glycerol accumulation in Trichoderma atroviride during osmotic
RT   stress.";
RL   Fungal Genet. Biol. 41:1132-1140(2004).
CC   -!- CATALYTIC ACTIVITY: sn-glycerol 3-phosphate + NAD(+) = glycerone
CC       phosphate + NADH.
CC   -!- SIMILARITY: Belongs to the NAD-dependent glycerol-3-phosphate
CC       dehydrogenase family.
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DR   EMBL; AY370658; AAR14209.1; -; Genomic_DNA.
DR   GO; GO:0009331; C:glycerol-3-phosphate dehydrogenase complex; IEA:InterPro.
DR   GO; GO:0004367; F:glycerol-3-phosphate dehydrogenase (NAD+) a...; IEA:InterPro.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0046168; P:glycerol-3-phosphate catabolic process; IEA:InterPro.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR013328; DHase_multihelical.
DR   InterPro; IPR016040; NAD(P)-bd.
DR   InterPro; IPR017751; NAD-dep_Gly3P_DH_euk.
DR   InterPro; IPR006168; NAD-dep_Gly3P_DHase.
DR   InterPro; IPR011128; NAD-dep_Gly3P_DHase_N.
DR   InterPro; IPR006109; NAD_Gly3P_DHase_C.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   Gene3D; G3DSA:1.10.1040.10; Opine_DH; 1.
DR   PANTHER; PTHR11728; NAD_Gly3P_DH; 1.
DR   Pfam; PF07479; NAD_Gly3P_dh_C; 1.
DR   Pfam; PF01210; NAD_Gly3P_dh_N; 1.
DR   PRINTS; PR00077; GPDHDRGNASE.
DR   ProDom; PD001278; NAD_Gly3P_C; 1.
DR   PROSITE; PS00957; NAD_G3PDH; 1.
PE   3: Inferred from homology;
KW   NAD; Oxidoreductase.
FT   CHAIN         1    427       Glycerol-3-phosphate dehydrogenase
FT                                [NAD+].
FT                                /FTId=PRO_0000138097.
FT   NP_BIND      17     22       NAD (By similarity).
FT   REGION      344    345       Substrate binding (By similarity).
FT   ACT_SITE    278    278       Proton acceptor (By similarity).
FT   BINDING     120    120       NAD (By similarity).
FT   BINDING     143    143       NAD; via amide nitrogen (By similarity).
FT   BINDING     143    143       Substrate (By similarity).
FT   BINDING     176    176       NAD; via amide nitrogen (By similarity).
FT   BINDING     344    344       NAD (By similarity).
FT   BINDING     373    373       NAD (By similarity).
SQ   SEQUENCE   427 AA;  46351 MW;  AF84DC639B08C90F CRC64;
     MAFLGGYEKK HKVTIVGSGN WGSTIAKIVA ENTRANKDVF EEDVQMWVFE EDVTIAKDSK
     HYDESIGDAP QKLTHVINKY HENVKYLPGI TLPSNIIANP SLVDAVQDSS ILIFNLPHQF
     IRNVCNQIRG KILPFARGIS CIKGVNVSDD GVSLFSEWIG DGLSIYVGAL SGANIASEIA
     AEKWSETTIA YDPPPMDNSR APTPRSQSPG LTMTVTEPPA DMQHRDARGR KSKTKLTPVP
     AEYPPLDHAC FHSLFHRPYF HVEMVSDVAG VSLGGALKNI VALAAGFVDG RGWGDNAKAA
     VMRIGLMEMV KFGKEFFGET VHTATFTESS AGVADLITSC SGGRNFRCAR KAVEKGITVD
     EVEKQDLNGQ KLQGTSTAFE VNSFLTARGL EKDYPLLTAV NAILLGKASV DDIPSLVSDT
     ERKQPLP
//