NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC BAA-98 / CGA009;
DOI=10.1038/nbt923; PubMed=14704707 [NCBI, ExPASy, EBI, Israel, Japan]
Larimer F.W., Chain P., Hauser L., Lamerdin J.E., Malfatti S., Do L., Land M.L., Pelletier D.A., Beatty J.T., Lang A.S., Tabita F.R., Gibson J.L., Hanson T.E., Bobst C., Torres y Torres J.L., Peres C., Harrison F.H., Gibson J., Harwood C.S.;
"Complete genome sequence of the metabolically versatile photosynthetic bacterium Rhodopseudomonas palustris.";
Nat. Biotechnol. 22:55-61(2004).

Comments

FUNCTION: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ (By similarity).
CATALYTIC ACTIVITY: 6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,5,6,7,8-octahydroquinoline-2,4-dicarboxylate + 3 O₂ = 4,5-dioxo-3a,4,5,6,7,8,9,9b-octahydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + 2 H₂O₂ + 2 H₂O.
PATHWAY: Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis .
SIMILARITY: Belongs to the pqqC family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

BX572599; CAE27389.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

NP_947293.1; -.

3D structure databases

ModBase

Q6N8F5.

Enzyme and pathway databases

BioCyc

RPAL258594:RPA1948-MON; -.

Ontologies

GO:0018189;	Biological process: pyrroloquinoline quinone biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_00654; -; 1.
PBIL [Tree]

InterPro

IPR016084; Haem_Oase-like_multi-hlx.
IPR011845; PQQ_synth_PqqC.
IPR004305; TENA/THI4/PQQ_synth_PqqC.
Graphical view of domain structure.

Gene3D

G3DSA:1.20.910.10; Haem_Oase-like_multi-hlx; 1.

Pfam

PF03070; TENA_THI-4; 1.
Pfam graphical view of domain structure.

TIGRFAMs

TIGR02111; PQQ_syn_pqqC; 1.

BLOCKS

Q6N8F5.

Genome annotation databases

GeneID

2688798; -.

GenomeReviews

BX571963_GR; RPA1948.

KEGG

rpa:RPA1948; -.

NMPDR

fig|258594.1.peg.1936; -.

Phylogenomic databases

HOGENOM

Q6N8F5; -.

Genome annotation databases

CMR

Q6N8F5; RPA1948.

Other

ProtoNet

Q6N8F5.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Oxidoreductase; PQQ biosynthesis.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 254`	`254`		`Pyrroloquinoline-quinone synthase.`	`PRO_0000219987`

Sequence information

Length: 254 AA [This is the length of the unprocessed precursor]

Molecular weight: 28618 Da [This is the MW of the unprocessed precursor]

CRC64: FCE79ADBCAA1E77F [This is a checksum on the sequence]

        10         20         30         40         50         60 
MNAMTAFSLN GAAPLANADE LEAALRQIGA ARYHNLHPFH RLLHGGKLNK GQVQAWALNR 

        70         80         90        100        110        120 
YYYQSSIPIK DAVVISRFRD RATRVEWRHR IEDHDGDLSS EGGIERWLKL TEGLGLDSGY 

       130        140        150        160        170        180 
VESTQGILPA TRFAVDAYVH FVRDRTPLEA IASSLTELFA PNLHEERIAG MLAHYDFVNP 

       190        200        210        220        230        240 
EIMSYFKRRL EQAPRDADFA LRHVKQHATT PAEREAVCNA LIFKTNVLWA QLDALHHAYV 

       250 
DGHIPPGAFV PQGF

Q6N8F5 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools