NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 15356 / HD100 / DSM 50701 / NCIB 9529;
DOI=10.1126/science.1093027; PubMed=14752164 [NCBI, ExPASy, EBI, Israel, Japan]
Rendulic S., Jagtap P., Rosinus A., Eppinger M., Baar C., Lanz C., Keller H., Lambert C., Evans K.J., Goesmann A., Meyer F., Sockett R.E., Schuster S.C.;
"A predator unmasked: life cycle of Bdellovibrio bacteriovorus from a genomic perspective.";
Science 303:689-692(2004).

Comments

FUNCTION: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions (By similarity).
CATALYTIC ACTIVITY: NTP + H₂O = NDP + phosphate.
COFACTOR: Divalent cations (By similarity).
SUBUNIT: Homodimer (By similarity).
SIMILARITY: Belongs to the HAM1 NTPase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

BX842653; CAE80492.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

NP_969499.1; -.

3D structure databases

HSSP

P52061; 1K7K. [HSSP ENTRY / PDB]

ModBase

Q6MJR8.

Enzyme and pathway databases

BioCyc

BBAC264462:BD2701-MON; -.

Ontologies

GO:0017111;	Molecular function: nucleoside-triphosphatase activity (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_01405; -; 1.
PBIL [Tree]

InterPro

IPR002637; Ham1p_like.
Graphical view of domain structure.

PANTHER

PTHR11067; Ham1p_like; 1.

Pfam

PF01725; Ham1p_like; 1.
Pfam graphical view of domain structure.

TIGRFAMs

TIGR00042; Ham1p_like; 1.

ProtoNet

Q6MJR8.

Genome annotation databases

2736218; -.

BX842601_GR; Bd2701.

bba:Bd2701; -.

fig|264462.1.peg.2471; -.

Phylogenomic databases

HOGENOM

Q6MJR8; -.

Genome annotation databases

CMR

Q6MJR8; Bd2701.

Other

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Hydrolase.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 199`	`199`		`Nucleoside-triphosphatase.`	`PRO_0000178133`

Sequence information

Length: 199 AA [This is the length of the unprocessed precursor]

Molecular weight: 21763 Da [This is the MW of the unprocessed precursor]

CRC64: C14A4D6E3718DE2E [This is a checksum on the sequence]

        10         20         30         40         50         60 
MELWIATGNK GKLAEYKQLL RELPDLKVFS QGDIASFTPR PEDGKTFEDN ARIKAKTLRA 

        70         80         90        100        110        120 
VKNNVWVLGE DAGLVVEGLN GLPGIHSARY AGPKASDSEN VSKLLKMITL RPMPNKNAKF 

       130        140        150        160        170        180 
VCTTVVYTPT GEEWVFNGEM KGTIASKPAG LHGFGYDPVF IPEGQTQTLA ELGTGYKSLL 

       190 
SHRAMALKAF LEKLQTVNP

Q6MJR8 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools