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UniProtKB/Swiss-Prot entry Q6MJE4

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name MAO1_BDEBA
Primary accession number Q6MJE4
Secondary accession numbers None
Integrated into Swiss-Prot on December 6, 2005
Sequence was last modified on July 5, 2004 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 29)
Name and origin of the protein
Protein name NAD-dependent malic enzyme
Synonyms NAD-ME
EC 1.1.1.38
Gene name
Name: sfcA
OrderedLocusNames: Bd2834
From
Bdellovibrio bacteriovorus [TaxID: 959] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Deltaproteobacteria; Bdellovibrionales; Bdellovibrionaceae; Bdellovibrio.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 15356 / HD100 / DSM 50701 / NCIB 9529;
DOI=10.1126/science.1093027; PubMed=14752164 [NCBI, ExPASy, EBI, Israel, Japan]
Rendulic S., Jagtap P., Rosinus A., Eppinger M., Baar C., Lanz C., Keller H., Lambert C., Evans K.J., Goesmann A., Meyer F., Sockett R.E., Schuster S.C.;
"A predator unmasked: life cycle of Bdellovibrio bacteriovorus from a genomic perspective.";
Science 303:689-692(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BX842653; CAE80616.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_969623.1; -.
3D structure databases
ModBase Q6MJE4.
Enzyme and pathway databases
BioCyc BBAC264462:BD2834-MON; -.
Ontologies
GO
GO:0016619; Molecular function: malate dehydrogenase (oxaloacetate-decarboxylating) activity (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01619; -; 1.
PBIL [Tree]
InterPro IPR015884; Malic_enzyme_CS.
IPR012301; Malic_N.
IPR012302; Malic_NAD_bd.
IPR001891; Malic_OxRdtase.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF00390; malic; 1.
PF03949; Malic_M; 1.
Pfam graphical view of domain structure.
PRINTS PR00072; MALOXRDTASE.
PROSITE PS00331; MALIC_ENZYMES; 1.
BLOCKS Q6MJE4.
Genome annotation databases
GeneID 2736386; -.
GenomeReviews BX842601_GR; Bd2834.
KEGG bba:Bd2834; -.
NMPDR fig|264462.1.peg.2595; -.
Phylogenomic databases
HOGENOM Q6MJE4; -.
Genome annotation databases
CMR Q6MJE4; Bd2834.
Other
ProtoNet Q6MJE4.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Metal-binding; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   565  565     NAD-dependent malic enzyme. PRO_0000160213
ACT_SITE   104   104        Proton donor (By similarity). 
ACT_SITE   175   175        Proton acceptor (By similarity). 
METAL   246   246        Divalent metal cation (By similarity). 
METAL   247   247        Divalent metal cation (By similarity). 
METAL   270   270        Divalent metal cation (By similarity). 
BINDING   157   157        NAD (By similarity). 
BINDING   270   270        NAD (By similarity). 
BINDING   418   418        NAD (By similarity). 
SITE   270   270  1     Important for activity (By similarity). 
Sequence information
Length: 565 AA [This is the length of the unprocessed precursor] Molecular weight: 62686 Da [This is the MW of the unprocessed precursor] CRC64: 6DAB2AFA0710B994 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
METDNKYARP VYIPYSGTVL LEMSLLNKGS AFSEEERTHL NLHGLVPQTI ETIEEQAERV 

        70         80         90        100        110        120 
YSQYRLLKAD IDKHVYLRNL QDTNETLFYH LVVNHLTEMM PIIYTPVVGE ACEHFSEIYR 

       130        140        150        160        170        180 
ASRGLFISYP NKDRIDEMLR NVTKQKVKVI VVTDGERILG LGDQGIGGMG IPIGKLSLYT 

       190        200        210        220        230        240 
ACGGISPAYT LPVVLDVGTN NQALLNDPLY MGWRQPRITG KEYEDFVDAF VQAVKRRWPD 

       250        260        270        280        290        300 
VLLQFEDFAQ KNASPILKRY RDEICSFNDD IQGTAAVTVG CLIAASRANG GRLRDQRVVF 

       310        320        330        340        350        360 
LGAGSAGCGI AEQIIAEMKH EGLSDEQARQ RVFMVDRFGL LTDKMPNLLE FQSPLVQKTE 

       370        380        390        400        410        420 
TLAGWEVTND EISLLDTVRN AKPTILIGVS AQPGLFTEEV IRTMQSHCEH PIVMPLSNPT 

       430        440        450        460        470        480 
SRVEATPADI LRWTDGKALV ATGSPFMPVH MNDQIYPIAQ CNNSYIFPGI GLGVLACGAR 

       490        500        510        520        530        540 
RVTDSMLMAA SSALADCSPL AQNGKGALLP ELSQIEKVSR TIAFAVAKAA QADEVAVKVS 

       550        560 
DEELLSLIDK NYWYPKYRSY KHASS
Q6MJE4 in FASTA format

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