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UniProtKB/Swiss-Prot entry Q6IRI9

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name FMO2_RAT
Primary accession number Q6IRI9
Secondary accession numbers None
Integrated into Swiss-Prot on October 25, 2005
Sequence was last modified on January 23, 2007 (Sequence version 3)
Annotations were last modified on    July 22, 2008 (Entry version 39)
Name and origin of the protein
Protein name Dimethylaniline monooxygenase [N-oxide-forming] 2
Synonyms EC 1.14.13.8
Pulmonary flavin-containing monooxygenase 2
FMO 2
Dimethylaniline oxidase 2
Gene name
Name: Fmo2
From
Rattus norvegicus (Rat) [TaxID: 10116] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
Protein existence 2: Evidence at transcript level;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Lung;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BC070904; AAH70904.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_653338.2; -.
UniGene Rn.3928
3D structure databases
ModBase Q6IRI9.
Organism-specific databases
RGD 628600; Fmo2.
Gene expression databases
ArrayExpress Q6IRI9; -.
GermOnline ENSRNOG00000003510; Rattus norvegicus.
Family and domain databases
InterPro IPR012143; dManiline_mOase.
IPR013027; FAD_pyr_nucl-diS_OxRdtase.
IPR000960; Flavin_mOase.
IPR002254; Flavin_mOase_2.
Graphical view of domain structure.
Pfam PF00743; FMO-like; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000332; FMO; 1.
PRINTS PR00368; FADPNR.
PR00370; FMOXYGENASE.
PR01122; FMOXYGENASE2.
ProDom PD000139; FAD_pyr_redox; 1.
[Domain structure / List of seq. sharing at least 1 domain]
BLOCKS Q6IRI9.
Genome annotation databases
Ensembl ENSRNOG00000003510; Rattus norvegicus. [Contig view]
GeneID 246245; -.
KEGG rno:246245; -.
Phylogenomic databases
HOVERGEN Q6IRI9; -.
Other
ProtoNet Q6IRI9.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Acetylation; Endoplasmic reticulum; FAD; Flavoprotein; Magnesium; Membrane; Microsome; Monooxygenase; NADP; Oxidoreductase; Transmembrane.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
INIT_MET   1     1        Removed (By similarity). 
CHAIN   2   535  534     Dimethylaniline monooxygenase [N-oxide-forming] 2. PRO_0000147651
NP_BIND   9    14  6     FAD (Potential). 
NP_BIND   191   196  6     NADP (Potential). 
MOD_RES   2     2        N-acetylvaline (By similarity). 
Sequence information
Length: 535 AA [This is the length of the unprocessed precursor] Molecular weight: 60899 Da [This is the MW of the unprocessed precursor] CRC64: 4BDABD847733F639 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MVKKVAVIGA GVSGLISLKG CVDEGLEPTC FERTEDIGGL WRFKENVEDG RASIYHSVIT 

        70         80         90        100        110        120 
NTSKEMSCFS DFPMPEDFPN FLHNSKLLEY FRIFAKKFDL LKYIQFQTTV ISVKKRPDFA 

       130        140        150        160        170        180 
SSGQWDVYVQ SNGKEQRAVF DAVMVCSGHH IQPHLPLKSF PGIERFQGQY FHSRQYKHPV 

       190        200        210        220        230        240 
GYEGKRILVV GIGNSAADIA SELSKRAAQV FVSTRHGSWV LSRISEDGYP WDMVFHTRFS 

       250        260        270        280        290        300 
SMLRNVLPRT VVKWMMERQM NRWFNHENYG LVPQNKYLMK EPVLNDDLPS RLLYGAIKVK 

       310        320        330        340        350        360 
TRVKELTETA VVFEDGTVEE DVDVIVFATG YTFSFPFLED SLVKVEDNKV SLYKAMFPPH 

       370        380        390        400        410        420 
LEKPTLACIG LIQPLGSIFP TVELQARWAT RVFKGVCRLP SETTMMADIA ERNEKRIDLF 

       430        440        450        460        470        480 
GKSQSQILQT NYIDYLDELA LEIGAKPDFI SLLFKDPKLA VKLYFGPCNS YQYRLVGPGQ 

       490        500        510        520        530 
WEGARNAILT QKQRILKPLK TRTLQTSASA PVSFLIKVLG LLAIVLAFFF KLHGF
Q6IRI9 in FASTA format

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