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UniProtKB/Swiss-Prot entry Q6HLF4

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ILVC1_BACHK
Primary accession number Q6HLF4
Secondary accession numbers None
Integrated into Swiss-Prot on March 7, 2006
Sequence was last modified on July 19, 2004 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 28)
Name and origin of the protein
Protein name Ketol-acid reductoisomerase 1
Synonyms EC 1.1.1.86
Acetohydroxy-acid isomeroreductase 1
Alpha-keto-beta-hydroxylacil reductoisomerase 1
Gene name
Name: ilvC1
OrderedLocusNames: BT9727_1283
From
Bacillus thuringiensis subsp. konkukian [TaxID: 180856] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus; Bacillus cereus group.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=97-27;
DOI=10.1128/JB.188.9.3382-3390.2006; PubMed=16621833 [NCBI, ExPASy, EBI, Israel, Japan]
Han C.S., Xie G., Challacombe J.F., Altherr M.R., Bhotika S.S., Bruce D., Campbell C.S., Campbell M.L., Chen J., Chertkov O., Cleland C., Dimitrijevic M., Doggett N.A., Fawcett J.J., Glavina T., Goodwin L.A., Hill K.K., Hitchcock P., Jackson P.J., Keim P., Kewalramani A.R., Longmire J., Lucas S., Malfatti S., McMurry K., Meincke L.J., Misra M., Moseman B.L., Mundt M., Munk A.C., Okinaka R.T., Parson-Quintana B., Reilly L.P., Richardson P., Robinson D.L., Rubin E., Saunders E., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H., Ticknor L.O., Wills P.L., Brettin T.S., Gilna P.;
"Pathogenomic sequence analysis of Bacillus cereus and Bacillus thuringiensis isolates closely related to Bacillus anthracis.";
J. Bacteriol. 188:3382-3390(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE017355; AAT62183.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_035617.1; -.
3D structure databases
ModBase Q6HLF4.
Enzyme and pathway databases
BioCyc BTHU281309:BT9727_1283-MON; -.
Ontologies
GO
GO:0004455; Molecular function: ketol-acid reductoisomerase activity (inferred from electronic annotation from HAMAP).
GO:0009097; Biological process: isoleucine biosynthetic process (inferred from electronic annotation from HAMAP).
GO:0009099; Biological process: valine biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00435; -; 1.
PBIL [Tree]
InterPro IPR013023; AcH_isomrdctse.
IPR000506; AcH_isomrdctse_C.
IPR013116; IlvN.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR21371; AcH_isomrdctse; 1.
Pfam PF01450; IlvC; 1.
PF07991; IlvN; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00465; ilvC; 1.
BLOCKS Q6HLF4.
Genome annotation databases
GeneID 2858689; -.
GenomeReviews AE017355_GR; BT9727_1283.
KEGG btk:BT9727_1283; -.
NMPDR fig|281309.1.peg.1257; -.
Phylogenomic databases
HOGENOM Q6HLF4; -.
Genome annotation databases
CMR Q6HLF4; BT9727_1283.
Other
ProtoNet Q6HLF4.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Branched-chain amino acid biosynthesis; Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   336  336     Ketol-acid reductoisomerase 1. PRO_0000226159
ACT_SITE   107   107        Potential. 
Sequence information
Length: 336 AA [This is the length of the unprocessed precursor] Molecular weight: 36779 Da [This is the MW of the unprocessed precursor] CRC64: 4049B6C0159A71D5 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MAKVYYEKDV TVNVLKEKKV AIIGYGSQGH AHAQNLRDNG FDVVVGLRKG KSWDKAKEDG 

        70         80         90        100        110        120 
FSVYTVAEAA KKADVVMILL PDELQPEVYE AEIAPNLQAG NSLVFAHGFN VHFDQVKPPV 

       130        140        150        160        170        180 
NVDVFLVAPK GPGHLVRRTF VEGGAVPALF AVYQDATGVA TEKALSYADG IGATRAGVLE 

       190        200        210        220        230        240 
TTFKEETETD LFGEQAVLCG GVTALVKAGF ETLVDAGYQP ELAYFECLHE LKLIVDLMYE 

       250        260        270        280        290        300 
GGLENMRYSV SDTAQWGDFV SGPRVVTEDT KKAMDTVLAE IQDGTFARGW IAEHKAGRPN 

       310        320        330 
FHATNEKENE HEIEVVGRKL REMMPFVQPR VKAGVK
Q6HLF4 in FASTA format

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