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UniProtKB/Swiss-Prot entry Q6G2T6


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ILVC_BARHE
Primary accession number Q6G2T6
Secondary accession numbers None
Integrated into Swiss-Prot on March 7, 2006
Sequence was last modified on July 19, 2004 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 25)
Name and origin of the protein
Protein name Ketol-acid reductoisomerase
Synonyms EC 1.1.1.86
Acetohydroxy-acid isomeroreductase
Alpha-keto-beta-hydroxylacil reductoisomerase
Gene name
Name: ilvC
OrderedLocusNames: BH10890
From
Bartonella henselae (Rochalimaea henselae) [TaxID: 38323] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Bartonellaceae; Bartonella.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 49882 / Houston 1;
DOI=10.1073/pnas.0305659101; PubMed=15210978 [NCBI, ExPASy, EBI, Israel, Japan]
Alsmark U.C.M., Frank A.C., Karlberg E.O., Legault B.-A., Ardell D.H., Canbaeck B., Eriksson A.-S., Naeslund A.K., Handley S.A., Huvet M., La Scola B., Holmberg M., Andersson S.G.E.;
"The louse-borne human pathogen Bartonella quintana is a genomic derivative of the zoonotic agent Bartonella henselae.";
Proc. Natl. Acad. Sci. U.S.A. 101:9716-9721(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BX897699; CAF27875.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_033864.1; -.
3D structure databases
ModBase Q6G2T6.
Enzyme and pathway databases
BioCyc BHEN283166:BH10890-MON; -.
Ontologies
GO
GO:0004455; Molecular function: ketol-acid reductoisomerase activity (inferred from electronic annotation from HAMAP).
GO:0009097; Biological process: isoleucine biosynthetic process (inferred from electronic annotation from HAMAP).
GO:0009099; Biological process: valine biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00435; -; 1.
PBIL [Tree]
InterPro IPR013023; AcH_isomrdctse.
IPR000506; AcH_isomrdctse_C.
IPR013116; IlvN.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR21371; AcH_isomrdctse; 1.
Pfam PF01450; IlvC; 1.
PF07991; IlvN; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00465; ilvC; 1.
BLOCKS Q6G2T6.
Genome annotation databases
GeneID 2865556; -.
GenomeReviews BX897699_GR; BH10890.
KEGG bhe:BH10890; -.
NMPDR fig|283166.1.peg.992; -.
Phylogenomic databases
HOGENOM Q6G2T6; -.
Genome annotation databases
CMR Q6G2T6; BH10890.
Other
ProtoNet Q6G2T6.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Branched-chain amino acid biosynthesis; Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   339  339     Ketol-acid reductoisomerase. PRO_0000226161
ACT_SITE   108   108        Potential. 
Sequence information
Length: 339 AA [This is the length of the unprocessed precursor] Molecular weight: 37350 Da [This is the MW of the unprocessed precursor] CRC64: 143769AB2CF2BFE3 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MRVYYDRDAN VNLIKEKKVA IVGYGSQGRA HALNLRDFGV KNVKIALRSE SATVKKAVAD 

        70         80         90        100        110        120 
GFEVVCVAEA AKWADLIMMA TPDELQADIY KEHIHDHLRD GAVIAFAHGL SIHFGLIEPK 

       130        140        150        160        170        180 
KTVDVVMIAP KGPGHTVRNE YQNGCGVPCL IAVAQDASGH AHNVALSYAC GLGGGRAGVI 

       190        200        210        220        230        240 
ETTFKEECET DLFGEQAVLC GGLVELIRAG YETLTEAGYA PEMAYFECLH EVKLIVDLMY 

       250        260        270        280        290        300 
EGGIANMNYS ISNTAEWGEY MSGPRVITDE TRAEMKRILK DIQTGKFTSN WIQEYKAGAA 

       310        320        330 
HFKGMRRLND SHPIEEVGKK LRSMMPWIKA NALVDKERN 

Q6G2T6 in FASTA format

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