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UniProtKB/Swiss-Prot entry Q6F821


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ILVC_ACIAD
Primary accession number Q6F821
Secondary accession numbers None
Integrated into Swiss-Prot on March 7, 2006
Sequence was last modified on July 19, 2004 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 37)
Name and origin of the protein
Protein name Ketol-acid reductoisomerase
Synonyms EC 1.1.1.86
Acetohydroxy-acid isomeroreductase
Alpha-keto-beta-hydroxylacil reductoisomerase
Gene name
Name: ilvC
OrderedLocusNames: ACIAD3102
From
Acinetobacter sp. (strain ADP1) [TaxID: 62977] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; Moraxellaceae; Acinetobacter.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1093/nar/gkh910; PubMed=15514110 [NCBI, ExPASy, EBI, Israel, Japan]
Barbe V., Vallenet D., Fonknechten N., Kreimeyer A., Oztas S., Labarre L., Cruveiller S., Robert C., Duprat S., Wincker P., Ornston L.N., Weissenbach J., Marliere P., Cohen G.N., Medigue C.;
"Unique features revealed by the genome sequence of Acinetobacter sp. ADP1, a versatile and naturally transformation competent bacterium.";
Nucleic Acids Res. 32:5766-5779(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CR543861; CAG69794.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_047616.1; -.
3D structure databases
SMR Q6F821; 1-327.
ModBase Q6F821.
Enzyme and pathway databases
BioCyc ASP62977:ACIAD3102-MON; -.
Ontologies
GO
GO:0004455; Molecular function: ketol-acid reductoisomerase activity (inferred from electronic annotation from HAMAP).
GO:0009097; Biological process: isoleucine biosynthetic process (inferred from electronic annotation from HAMAP).
GO:0009099; Biological process: valine biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00435; -; 1.
PBIL [Tree]
InterPro IPR013023; AcH_isomrdctse.
IPR000506; AcH_isomrdctse_C.
IPR013116; IlvN.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR21371; AcH_isomrdctse; 1.
Pfam PF01450; IlvC; 1.
PF07991; IlvN; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00465; ilvC; 1.
BLOCKS Q6F821.
Genome annotation databases
GeneID 2877810; -.
GenomeReviews CR543861_GR; ACIAD3102.
KEGG aci:ACIAD3102; -.
NMPDR fig|62977.3.peg.2809; -.
Phylogenomic databases
HOGENOM Q6F821; -.
Genome annotation databases
CMR Q6F821; ACIAD3102.
Other
ProtoNet Q6F821.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Branched-chain amino acid biosynthesis; Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   338  338     Ketol-acid reductoisomerase. PRO_0000226153
ACT_SITE   107   107        Potential. 
Sequence information
Length: 338 AA [This is the length of the unprocessed precursor] Molecular weight: 36943 Da [This is the MW of the unprocessed precursor] CRC64: 1564789A03851645 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MQIFYDKDCD LSIIQGKKVA IIGYGSQGHA HALNLKDSGV DVTVGLRANS ASWKKAENAG 

        70         80         90        100        110        120 
LKVAEVPEAV KQADLVMILT PDEFQSQLYR DVIEPNIKEG ATLAFAHGFS VLYNQVVPRQ 

       130        140        150        160        170        180 
DLDVIMVAPK APGHTVRSEF QRGSGVPDLI AIHQDASGNA RNVALSYASG VGGGRTGIIE 

       190        200        210        220        230        240 
TSFREETETD LFGEQAVLCG GAVELVKMGF ETLVEAGYSP EMAYFECLHE LKLIVDLMFE 

       250        260        270        280        290        300 
GGIADMNYSV SNNAEYGEYV TGVEVINEQS REAMRNALKR IQSGEYAKMF IQEGALNYPS 

       310        320        330 
MTARRRQNAA HGIEVTGSKL RAMMPWIQAN KIVDKEKN 

Q6F821 in FASTA format

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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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