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UniProtKB/Swiss-Prot entry Q6CX23


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name G3P2_KLULA
Primary accession number Q6CX23
Secondary accession numbers None
Integrated into Swiss-Prot on October 11, 2004
Sequence was last modified on August 16, 2004 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 33)
Name and origin of the protein
Protein name Glyceraldehyde-3-phosphate dehydrogenase 2
Synonyms GAPDH 2
EC 1.2.1.12
Gene name
Name: GAP2
OrderedLocusNames: KLLA0A11858g
From
Kluyveromyces lactis (Yeast) (Candida sphaerica) [TaxID: 28985] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NRRL Y-1140 / WM37;
DOI=10.1038/nature02579; PubMed=15229592 [NCBI, ExPASy, EBI, Israel, Japan]
Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S., Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J., Wincker P., Souciet J.-L.;
"Genome evolution in yeasts.";
Nature 430:35-44(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CR382121; CAH03104.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq XP_451516.1; -.
3D structure databases
SMR Q6CX23; 1-329.
ModBase Q6CX23.
Family and domain databases
InterPro IPR000173; GlycerAld_3-P_DHase.
IPR006424; Glyceraldehyde-3-P_DHase_1.
Graphical view of domain structure.
PANTHER PTHR10836; GAP_DH; 1.
Pfam PF02800; Gp_dh_C; 1.
PF00044; Gp_dh_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000149; GAP_DH; 1.
PRINTS PR00078; G3PDHDRGNASE.
TIGRFAMs TIGR01534; GAPDH-I; 1.
PROSITE PS00071; GAPDH; 1.
BLOCKS Q6CX23.
Genome annotation databases
GeneID 2896666; -.
KEGG kla:KLLA0A11858g; -.
Phylogenomic databases
HOGENOM Q6CX23; -.
Other
ProtoNet Q6CX23.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; Glycolysis; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   331  331     Glyceraldehyde-3-phosphate dehydrogenase 2. PRO_0000145557
NP_BIND   11    12  2     NAD (By similarity). 
REGION   148   150  3     Glyceraldehyde 3-phosphate binding (By similarity). 
REGION   208   209  2     Glyceraldehyde 3-phosphate binding (By similarity). 
ACT_SITE   149   149        Nucleophile (By similarity). 
BINDING   33    33        NAD (By similarity). 
BINDING   78    78        NAD; via carbonyl oxygen (By similarity). 
BINDING   179   179        Glyceraldehyde 3-phosphate (By similarity). 
BINDING   231   231        Glyceraldehyde 3-phosphate (By similarity). 
BINDING   313   313        NAD (By similarity). 
SITE   176   176  1     Activates thiol group during catalysis (By similarity). 
Sequence information
Length: 331 AA [This is the length of the unprocessed precursor] Molecular weight: 35546 Da [This is the MW of the unprocessed precursor] CRC64: E0E2A1400ECDF7A2 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MVRVAINGFG RIGRLVLRIA LSRPNVEVVA INDPFISVDY AAYMFKYDST HGRFAGEVSH 

        70         80         90        100        110        120 
DENSLIIDGK KVLVFQERDP ATLPWGEHNV DIAIDSTGVF KELDSAQKHI DAGAKKVVIT 

       130        140        150        160        170        180 
APSSTAPMFV VGVNEDKYNG ETIVSNASCT TNCLAPLAKV VNNAFGIEEG LMSTIHSITA 

       190        200        210        220        230        240 
TQKTVDGPSQ KDWRGGRTAS GNIIPSSTGA AKAVGKVLPE LQGKLTGMAF RVPTVDVSVV 

       250        260        270        280        290        300 
DLTVKLAKEA TYDEIKAVIK KASENELKGI LGYTEDAVVS SDFLGDTNSS IFDAAAGIQL 

       310        320        330 
SPKFVKLVTW YDNEYGYSTR VVDLVELVAK N 

Q6CX23 in FASTA format

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