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UniProtKB/Swiss-Prot entry Q6CIC9


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name JHD1_KLULA
Primary accession number Q6CIC9
Secondary accession numbers None
Integrated into Swiss-Prot on March 7, 2006
Sequence was last modified on August 16, 2004 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 31)
Name and origin of the protein
Protein name JmjC domain-containing histone demethylation protein 1
Synonyms EC 1.14.11.27
[Histone-H3]-lysine-36 demethylase 1
Gene name
Name: JHD1
OrderedLocusNames: KLLA0F27643g
From
Kluyveromyces lactis (Yeast) (Candida sphaerica) [TaxID: 28985] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NRRL Y-1140 / WM37;
DOI=10.1038/nature02579; PubMed=15229592 [NCBI, ExPASy, EBI, Israel, Japan]
Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S., Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J., Wincker P., Souciet J.-L.;
"Genome evolution in yeasts.";
Nature 430:35-44(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CR382126; CAG99018.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq XP_456310.1; -.
3D structure databases
ModBase Q6CIC9.
Ontologies
GO
GO:0051864; Molecular function: histone demethylase activity (H3-K36 specific) (inferred from electronic annotation from EC).
QuickGo view.
Family and domain databases
InterPro IPR003347; TF_JmjC_AAH.
IPR001965; Znf_PHD.
Graphical view of domain structure.
SMART SM00558; JmjC; 1.
SM00249; PHD; 1.
SMART graphical view of domain structure.
PROSITE PS51184; JMJC; 1.
PS01359; ZF_PHD_1; FALSE_NEG.
PS50016; ZF_PHD_2; FALSE_NEG.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q6CIC9.
Genome annotation databases
GeneID 2894869; -.
KEGG kla:KLLA0F27643g; -.
Phylogenomic databases
HOGENOM Q6CIC9; -.
Other
ProtoNet Q6CIC9.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Chromatin regulator; Complete proteome; Dioxygenase; Iron; Metal-binding; Nucleus; Oxidoreductase; Transcription; Transcription regulation; Zinc; Zinc-finger.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   478  478     JmjC domain-containing histone demethylation protein 1. PRO_0000226798
DOMAIN   242   401  160     JmjC. 
ZN_FING   6    70  65     PHD-type. 
METAL   297   297        Iron (catalytic) (By similarity). 
METAL   299   299        Iron (catalytic) (By similarity). 
METAL   369   369        Iron (catalytic) (By similarity). 
BINDING   294   294        Substrate (By similarity). 
BINDING   314   314        Substrate (By similarity). 
Sequence information
Length: 478 AA [This is the length of the unprocessed precursor] Molecular weight: 54963 Da [This is the MW of the unprocessed precursor] CRC64: F282BD749A1F1EF2 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MTSGTVKCHF CKKDDSEDKG QPIWVGCEFC DGWCHLTCVP IQFVVPKLEN PSQLLAFKEK 

        70         80         90        100        110        120 
HVESFKCTLH DESKCALLKL NGVSVGTEDI AFTKRNRLRN KRPIDYIALN EGNDKRLKHE 

       130        140        150        160        170        180 
HPHTQAFLAC FEKWKDPKAI SSSELESDFQ IIKVPLRVSD PADSGMYVIS ANELGLVDSK 

       190        200        210        220        230        240 
DHVKLNVEYL TKIMGDDYPL DVMDVQTQMN EKWTLSQWNE YYSHTSPSDR DRIRNVISLE 

       250        260        270        280        290        300 
VSHVESFKDG IRRPNAVNNN DLVDIVWNFG RTETDIERPK VTKYILMSVG NAYTDFHLDF 

       310        320        330        340        350        360 
AGTSVYYNVI SGSKKFILFP PTDYNLKKYR EWCDNDNQND IFLGDQLEAG IAMELTEGNL 

       370        380        390        400        410        420 
FMIPCGYIHA VYTPEDSFIV GGNFLTLRDI TTQLNVVEIE HQTKVPKKFT FPQFESVMGK 

       430        440        450        460        470 
TCEWLLNSDH IQSISSEDIE NLVKYLSSSN IKYKPINYQS KKELITELKN KIIKFEHT 

Q6CIC9 in FASTA format

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