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UniProtKB/Swiss-Prot entry Q6C423


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name JHD1_YARLI
Primary accession number Q6C423
Secondary accession numbers None
Integrated into Swiss-Prot on March 7, 2006
Sequence was last modified on August 16, 2004 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 32)
Name and origin of the protein
Protein name JmjC domain-containing histone demethylation protein 1
Synonyms EC 1.14.11.27
[Histone-H3]-lysine-36 demethylase 1
Gene name
Name: JHD1
OrderedLocusNames: YALI0E30393g
From
Yarrowia lipolytica (Candida lipolytica) [TaxID: 4952] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Dipodascaceae; Yarrowia.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=CLIB 122 / E 150;
DOI=10.1038/nature02579; PubMed=15229592 [NCBI, ExPASy, EBI, Israel, Japan]
Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S., Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J., Wincker P., Souciet J.-L.;
"Genome evolution in yeasts.";
Nature 430:35-44(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CR382131; CAG80193.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq XP_504589.1; -.
3D structure databases
ModBase Q6C423.
Family and domain databases
InterPro IPR013129; TF_JmjC.
IPR003347; TF_JmjC_AAH.
IPR001965; Znf_PHD.
IPR013083; Znf_RING/FYVE/PHD.
Graphical view of domain structure.
Gene3D G3DSA:3.30.40.10; Znf_RING/FYVE/PHD; 1.
Pfam PF02373; JmjC; 1.
PF00628; PHD; 1.
Pfam graphical view of domain structure.
SMART SM00558; JmjC; 1.
SM00249; PHD; 1.
SMART graphical view of domain structure.
PROSITE PS51184; JMJC; 1.
PS01359; ZF_PHD_1; FALSE_NEG.
PS50016; ZF_PHD_2; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q6C423.
Genome annotation databases
GeneID 2912961; -.
KEGG yli:YALI0E30393g; -.
Phylogenomic databases
HOGENOM Q6C423; -.
Other
ProtoNet Q6C423.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Chromatin regulator; Complete proteome; Dioxygenase; Iron; Metal-binding; Nucleus; Oxidoreductase; Transcription; Transcription regulation; Zinc; Zinc-finger.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   510  510     JmjC domain-containing histone demethylation protein 1. PRO_0000226800
DOMAIN   216   365  150     JmjC. 
ZN_FING   2    53  52     PHD-type. 
METAL   258   258        Iron; catalytic (By similarity). 
METAL   260   260        Iron; catalytic (By similarity). 
METAL   333   333        Iron; catalytic (By similarity). 
BINDING   255   255        Substrate (By similarity). 
BINDING   275   275        Substrate (By similarity). 
Sequence information
Length: 510 AA [This is the length of the unprocessed precursor] Molecular weight: 57824 Da [This is the MW of the unprocessed precursor] CRC64: AF2ACF8B12D39990 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MPNRCDFCTS SSTKDKQQWT QCDGCDRWVH DVCVSITDPV SYAKYHCPTC TKTKGPSLYK 

        70         80         90        100        110        120 
RQSKRKKIDI DYAAMHSGNV DMSLRTRHVH SSRFTDVAAS AQNKEPFKRV SGTELTLDWA 

       130        140        150        160        170        180 
QSSDGLNEPV IVPKEYKDTL GMYIPEDLTV RQVAEAVGME SPVEVINVVS QNGSPGWNMG 

       190        200        210        220        230        240 
KWTEYYEDIE GRDTILNVIS LEISASALGK TIVRPTLVRE LDLVDRVWPT NTDAARESKP 

       250        260        270        280        290        300 
RVSLYALMSV EDSFTDFHID FAGSSVFYHV LKGRKSFMFI RPTARNLAAY SQWCLSADQN 

       310        320        330        340        350        360 
VVFLPDVLSP DSDIYTVHLS PGDTMYIPSG WIHAVHSPQD SLVVGGNFIT PLNMKTQIDI 

       370        380        390        400        410        420 
AGIEVRTKVP MKFRYPLFAG VMWYYVLQLL ANPERLNTMS TKERDGLNSV AEYLSGFIKT 

       430        440        450        460        470        480 
MSPTMKDVQY RRFVANFPME IRPFPGKTLL DYCAMLDFYP KGVQETVDID IRKKKGESKE 

       490        500        510 
KHKIESQLPE EKILQGSKLE SKEEVQTENF 

Q6C423 in FASTA format

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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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