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UniProtKB/Swiss-Prot entry Q6BXJ4


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name JHD1_DEBHA
Primary accession number Q6BXJ4
Secondary accession numbers None
Integrated into Swiss-Prot on March 7, 2006
Sequence was last modified on August 16, 2004 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 32)
Name and origin of the protein
Protein name JmjC domain-containing histone demethylation protein 1
Synonyms EC 1.14.11.27
[Histone-H3]-lysine-36 demethylase 1
Gene name
Name: JHD1
OrderedLocusNames: DEHA0B02519g
From
Debaryomyces hansenii (Yeast) (Torulaspora hansenii) [TaxID: 4959] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Debaryomyces.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 36239 / CBS 767 / IFO 0083 / IGC 2968 / JCM 1990;
DOI=10.1038/nature02579; PubMed=15229592 [NCBI, ExPASy, EBI, Israel, Japan]
Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S., Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J., Wincker P., Souciet J.-L.;
"Genome evolution in yeasts.";
Nature 430:35-44(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CR382134; CAG85063.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq XP_457075.1; -.
3D structure databases
ModBase Q6BXJ4.
Family and domain databases
InterPro IPR013129; TF_JmjC.
IPR003347; TF_JmjC_AAH.
IPR001965; Znf_PHD.
IPR013083; Znf_RING/FYVE/PHD.
Graphical view of domain structure.
Gene3D G3DSA:3.30.40.10; Znf_RING/FYVE/PHD; 1.
Pfam PF02373; JmjC; 1.
PF00628; PHD; 1.
Pfam graphical view of domain structure.
SMART SM00558; JmjC; 1.
SM00249; PHD; 1.
SMART graphical view of domain structure.
PROSITE PS51184; JMJC; 1.
PS01359; ZF_PHD_1; 1.
PS50016; ZF_PHD_2; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q6BXJ4.
Genome annotation databases
GeneID 2913011; -.
KEGG dha:DEHA0B02519g; -.
Phylogenomic databases
HOGENOM Q6BXJ4; -.
Other
ProtoNet Q6BXJ4.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Chromatin regulator; Complete proteome; Dioxygenase; Iron; Metal-binding; Nucleus; Oxidoreductase; Transcription; Transcription regulation; Zinc; Zinc-finger.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   514  514     JmjC domain-containing histone demethylation protein 1. PRO_0000226796
DOMAIN   220   384  165     JmjC. 
ZN_FING   4    62  59     PHD-type. 
METAL   270   270        Iron; catalytic (By similarity). 
METAL   272   272        Iron; catalytic (By similarity). 
METAL   352   352        Iron; catalytic (By similarity). 
BINDING   267   267        Substrate (By similarity). 
BINDING   287   287        Substrate (By similarity). 
Sequence information
Length: 514 AA [This is the length of the unprocessed precursor] Molecular weight: 58737 Da [This is the MW of the unprocessed precursor] CRC64: BA0A47774D48D8C0 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MPDIDTCPIC VESPLEDSTT FNNIAWLQCD ICNQWFHASC LKIPKIEVNN LHSYHCEGCS 

        70         80         90        100        110        120 
KSHGPSIPKR KLKRSKVQID YVALNDGDVF AVDKSLHPHV DKFLSFEVNA NEIDDKINPY 

       130        140        150        160        170        180 
IDFRKDITAD YALDTRLTRP VLIPRADLDI VDMKLPIEGK EITIDYIANE VGDDTPLDVM 

       190        200        210        220        230        240 
DVLTQQGVNP GWNLGKWRDY YNTDELSRDR IRNVISLEIS DVDSFGKSFR RPRIVRDMDL 

       250        260        270        280        290        300 
VDKVWNDKSP RPKVTKYCLM SVTGSFTDFH IDFSGTSVYY TVCSGSKTFL MYPPTEQNLD 

       310        320        330        340        350        360 
IYTSWCLQPD QNYMWFGDFT KAFKGKGCTP SGGFKVTLSP GDLFIIPSGW IHAVFTPEDS 

       370        380        390        400        410        420 
LVIGGNFLTL MDLSMHLRIY EIEKVTRVPA KFRFPMFNRV LWLTSWYYYN NKSQFLKDLG 

       430        440        450        460        470        480 
QDAHIKNEAH IKSEAHSRGE VHTKTETHAV KDEPQPDQSV QYKTLSCLVS HLQSHYESSK 

       490        500        510 
INKVARNTIP AGLIGKDIPG YLAKLQSWLD ELSP 

Q6BXJ4 in FASTA format

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